FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2892011739> ?p ?o ?g. }

• W2892011739 endingPage "e494" @default.
• W2892011739 startingPage "e494" @default.
• W2892011739 abstract "With interest, we read the recently published article by Proneth et al on the use of expanded criteria pancreas allografts and we congratulate the authors on the completion of this study.1 The study describes 79 pancreas transplantations, with 17 pancreata from donors between ages of 50 and 60 years and 1 pancreas from a donor with a body mass index between 30 and 34 kg/m2. The authors rightfully conclude that pancreas transplantations with organs from these “older” donors yield good outcome with similar graft survival. Due to organ shortage, increasing donor age is observed in all fields of transplantation. For pancreata, professionals are reluctant to accept organs from older donors, mostly due to the increased risk of graft thrombosis and pancreatitis. Despite these risks, the maximum donor age for acceptable pancreata in donation after brain death donors has in some countries already been expanded to 60 years.2,3 Also, increasing numbers of donation after circulatory death pancreas transplantation are reported with excellent outcome.2,4 However, as authors state, due to legislation, this is not allowed in Germany. Key elements incorporated for successful extension of donor limits by this study included local organ procurement to minimize ischemic time and the option to assess organ quality by the local team.1 All extended donor criteria (EDC) donors being explanted and transplanted by the 4 participating high-volume centers introduced a substantial bias. As also referred to by the authors, high-volume centers show better graft survival when transplanting pancreata with increased risk factors.5 Furthermore, experienced donor surgeons from pancreas transplant centers have a smaller risk of surgical organ injuries during abdominal organ recovery as compared with surgeons from centers not performing pancreas transplantation.6 The inclusion of only 79 pancreata and 18 EDC pancreata in more than 3 years still suggests a very strict selection, reflected in a minimal extension of donor age with a mean age of 51.4 years in the EDC group. Although being the strongest risk factor, there are more donor factors predicting outcome after transplantation. Axelrod et al7 weighed and combined these parameters in a continuous scoring tool: the Pancreas Donor Risk Index. If calculated in this study, we hypothesize that the Pancreas Donor Risk Index would be equal for both groups. Again, indicating a very strict donor selection for the EDC group. Therefore, it would have been interesting to also research the number and criteria of pancreata that were not accepted for transplantation within the study period. In general, some regions are more defensive in accepting organs than others.3 The Extended Pancreas Donor Program (EXPAND) study shows that pancreata from donors older than 50 years can successfully be used for pancreas transplantation. Again, we congratulate the authors on their efforts to conduct this study and their publication. Hopefully, this initiative will be continued. With a mean donor age of just older than 50 years in the EDC group and the majority of transplantations being performed in low volume centers, there seem to be options to even further expand the number of pancreas transplantations." @default.
• W2892011739 created "2018-09-27" @default.
• W2892011739 creator A5067798402 @default.
• W2892011739 creator A5071704700 @default.
• W2892011739 creator A5075225415 @default.
• W2892011739 creator A5090863984 @default.
• W2892011739 date "2018-12-01" @default.
• W2892011739 modified "2023-10-03" @default.
• W2892011739 title "How Far Can We Expand Donor Age Criteria for Pancreas Transplantation?" @default.
• W2892011739 cites W2003444455 @default.
• W2892011739 cites W2046941083 @default.
• W2892011739 cites W2399261207 @default.
• W2892011739 cites W2460987893 @default.
• W2892011739 cites W2579848933 @default.
• W2892011739 cites W2794437522 @default.
• W2892011739 doi "https://doi.org/10.1097/tp.0000000000002438" @default.
• W2892011739 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30188415" @default.
• W2892011739 hasPublicationYear "2018" @default.
• W2892011739 type Work @default.
• W2892011739 sameAs 2892011739 @default.
• W2892011739 citedByCount "4" @default.
• W2892011739 countsByYear W28920117392018 @default.
• W2892011739 countsByYear W28920117392020 @default.
• W2892011739 countsByYear W28920117392021 @default.
• W2892011739 countsByYear W28920117392022 @default.
• W2892011739 crossrefType "journal-article" @default.
• W2892011739 hasAuthorship W2892011739A5067798402 @default.
• W2892011739 hasAuthorship W2892011739A5071704700 @default.
• W2892011739 hasAuthorship W2892011739A5075225415 @default.
• W2892011739 hasAuthorship W2892011739A5090863984 @default.
• W2892011739 hasBestOaLocation W28920117392 @default.
• W2892011739 hasConcept C126322002 @default.
• W2892011739 hasConcept C138885662 @default.
• W2892011739 hasConcept C141071460 @default.
• W2892011739 hasConcept C162324750 @default.
• W2892011739 hasConcept C194051981 @default.
• W2892011739 hasConcept C2775933685 @default.
• W2892011739 hasConcept C2778064082 @default.
• W2892011739 hasConcept C2778137410 @default.
• W2892011739 hasConcept C2778764654 @default.
• W2892011739 hasConcept C2780303639 @default.
• W2892011739 hasConcept C2911091166 @default.
• W2892011739 hasConcept C2994510829 @default.
• W2892011739 hasConcept C41895202 @default.
• W2892011739 hasConcept C50522688 @default.
• W2892011739 hasConcept C71924100 @default.
• W2892011739 hasConceptScore W2892011739C126322002 @default.
• W2892011739 hasConceptScore W2892011739C138885662 @default.
• W2892011739 hasConceptScore W2892011739C141071460 @default.
• W2892011739 hasConceptScore W2892011739C162324750 @default.
• W2892011739 hasConceptScore W2892011739C194051981 @default.
• W2892011739 hasConceptScore W2892011739C2775933685 @default.
• W2892011739 hasConceptScore W2892011739C2778064082 @default.
• W2892011739 hasConceptScore W2892011739C2778137410 @default.
• W2892011739 hasConceptScore W2892011739C2778764654 @default.
• W2892011739 hasConceptScore W2892011739C2780303639 @default.
• W2892011739 hasConceptScore W2892011739C2911091166 @default.
• W2892011739 hasConceptScore W2892011739C2994510829 @default.
• W2892011739 hasConceptScore W2892011739C41895202 @default.
• W2892011739 hasConceptScore W2892011739C50522688 @default.
• W2892011739 hasConceptScore W2892011739C71924100 @default.
• W2892011739 hasIssue "12" @default.
• W2892011739 hasLocation W28920117391 @default.
• W2892011739 hasLocation W28920117392 @default.
• W2892011739 hasLocation W28920117393 @default.
• W2892011739 hasOpenAccess W2892011739 @default.
• W2892011739 hasPrimaryLocation W28920117391 @default.
• W2892011739 hasRelatedWork W1966110307 @default.
• W2892011739 hasRelatedWork W1997621633 @default.
• W2892011739 hasRelatedWork W2134025430 @default.
• W2892011739 hasRelatedWork W2360365649 @default.
• W2892011739 hasRelatedWork W2398182259 @default.
• W2892011739 hasRelatedWork W2416019662 @default.
• W2892011739 hasRelatedWork W2430076813 @default.
• W2892011739 hasRelatedWork W2789886359 @default.
• W2892011739 hasRelatedWork W2802636355 @default.
• W2892011739 hasRelatedWork W2910622970 @default.
• W2892011739 hasVolume "102" @default.
• W2892011739 isParatext "false" @default.
• W2892011739 isRetracted "false" @default.
• W2892011739 magId "2892011739" @default.
• W2892011739 workType "article" @default.