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- W2892017835 abstract "Abstract The separation of chiral compounds is an interesting and important topic of research because these compounds are involved in some biological processes, fundamentally in human health. Among the various application fields where enantiomers are remarkable, drug analysis has to be considered. Most of the drugs contain enantiomers and very often one of the two isomers could be pharmacologically more active or even dangerous. Therefore, the separation of these compounds is very important. Among the different analytical techniques usually employed, capillary electrochromatography has demonstrated great capability in enantiomers resolution. The great potential of this electromigration technique stands mainly in its high efficiency due to the use of an electrosmotic flow (flat flow profile) and on the high selectivity because of the use of a stationary phase. Chiral separation can be obtained utilizing several chiral stationary phases including a polysaccharide derivative. The aim of this review paper is to summarize the main features of capillary electrochromatography and polysaccharide derivatives of chiral stationary phase. It also report examples of practical applications utilizing this approach." @default.
- W2892017835 created "2018-09-27" @default.
- W2892017835 creator A5009090739 @default.
- W2892017835 creator A5013600942 @default.
- W2892017835 creator A5041308926 @default.
- W2892017835 date "2018-10-08" @default.
- W2892017835 modified "2023-10-12" @default.
- W2892017835 title "Enantiomers separation by capillary electrochromatography using polysaccharide-based stationary phases" @default.
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- W2892017835 doi "https://doi.org/10.1002/jssc.201800798" @default.
- W2892017835 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30198206" @default.
- W2892017835 hasPublicationYear "2018" @default.
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