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- W2892030934 abstract "RNA interference (RNAi), which is mediated by small interfering RNAs (siRNAs) derived from viral genome or its replicative intermediates, is a natural antiviral defense in plants, fungi, and invertebrates. Whether RNAi naturally protects humans from viral invasion is still a matter of debate. Nevertheless, exogenous siRNAs are able to halt viral infection in mammals. The current review critically evaluates the production of antiviral siRNAs, delivery techniques to the infection sites, as well as provides an overview of antiviral siRNAs in clinical trials." @default.
- W2892030934 created "2018-09-27" @default.
- W2892030934 creator A5059563431 @default.
- W2892030934 creator A5071726265 @default.
- W2892030934 date "2018-09-11" @default.
- W2892030934 modified "2023-10-14" @default.
- W2892030934 title "RNA Interference as a Prospective Tool for the Control of Human Viral Infections" @default.
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- W2892030934 doi "https://doi.org/10.3389/fmicb.2018.02151" @default.
- W2892030934 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6141738" @default.
- W2892030934 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30254624" @default.
- W2892030934 hasPublicationYear "2018" @default.
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