FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2892032685> ?p ?o ?g. }

• W2892032685 endingPage "17204" @default.
• W2892032685 startingPage "17201" @default.
• W2892032685 abstract "Abstract Cross‐coupling reactions catalyzed by transition metals are among the most influential in modern synthetic chemistry. The vast majority of transition‐metal‐catalyzed cross‐couplings rely on a catalytic cycle involving alternating oxidation and reduction of the metal center and are generally limited to forging just one type of new bond per reaction (e.g., the biaryl linkage formed during a Suzuki cross‐coupling). This work presents an Isohypsic‐Redox Sequence (IRS) that uses one metal to effect two catalytic cycles, thereby generating multiple new types of bonds from a single catalyst source. We show that the IRS strategy is amenable to several widely used transformations including the Suzuki–Miyaura coupling, Buchwald–Hartwig amination, and Wacker oxidation. Furthermore, each of these reactions generates value‐added heterocycles with significant sp 3 ‐C (3‐dimensional) content. Our results provide a general framework for generating complex products by using a single metal to fulfill multiple roles. By uniting different combinations of reactions in the isohypsic and redox phases of the process, this type of catalytic multiple bond‐forming platform has the potential for wide applicability in the efficient synthesis of functional organic molecules." @default.
• W2892032685 created "2018-09-27" @default.
• W2892032685 creator A5020323997 @default.
• W2892032685 creator A5024857340 @default.
• W2892032685 creator A5032672725 @default.
• W2892032685 creator A5073439057 @default.
• W2892032685 date "2018-11-02" @default.
• W2892032685 modified "2023-10-14" @default.
• W2892032685 title "Catalytic Isohypsic-Redox Sequences for the Rapid Generation of C_sp3 -Containing Heterocycles" @default.
• W2892032685 cites W1957097051 @default.
• W2892032685 cites W1967729000 @default.
• W2892032685 cites W1969487950 @default.
• W2892032685 cites W1970316257 @default.
• W2892032685 cites W1970886364 @default.
• W2892032685 cites W1975237431 @default.
• W2892032685 cites W1982832174 @default.
• W2892032685 cites W1985462077 @default.
• W2892032685 cites W1986119632 @default.
• W2892032685 cites W2003317678 @default.
• W2892032685 cites W2004867175 @default.
• W2892032685 cites W2006973236 @default.
• W2892032685 cites W2010203141 @default.
• W2892032685 cites W2017416802 @default.
• W2892032685 cites W2026904950 @default.
• W2892032685 cites W2027401817 @default.
• W2892032685 cites W2029040745 @default.
• W2892032685 cites W2032294371 @default.
• W2892032685 cites W2034082393 @default.
• W2892032685 cites W2036616637 @default.
• W2892032685 cites W2037964091 @default.
• W2892032685 cites W2040702384 @default.
• W2892032685 cites W2044673682 @default.
• W2892032685 cites W2046366153 @default.
• W2892032685 cites W2060781858 @default.
• W2892032685 cites W2061142370 @default.
• W2892032685 cites W2063764657 @default.
• W2892032685 cites W2071191072 @default.
• W2892032685 cites W2074274985 @default.
• W2892032685 cites W2079461626 @default.
• W2892032685 cites W2083611358 @default.
• W2892032685 cites W2083790594 @default.
• W2892032685 cites W2090868382 @default.
• W2892032685 cites W2093698530 @default.
• W2892032685 cites W2100142235 @default.
• W2892032685 cites W2103400238 @default.
• W2892032685 cites W2105889873 @default.
• W2892032685 cites W2109638239 @default.
• W2892032685 cites W2109767300 @default.
• W2892032685 cites W2110089307 @default.
• W2892032685 cites W2111729898 @default.
• W2892032685 cites W2113914309 @default.
• W2892032685 cites W2114619507 @default.
• W2892032685 cites W2117002481 @default.
• W2892032685 cites W2123331492 @default.
• W2892032685 cites W2126541092 @default.
• W2892032685 cites W2130009017 @default.
• W2892032685 cites W2141698925 @default.
• W2892032685 cites W2143356381 @default.
• W2892032685 cites W2143604271 @default.
• W2892032685 cites W2144226812 @default.
• W2892032685 cites W2144414888 @default.
• W2892032685 cites W2152552837 @default.
• W2892032685 cites W2160574842 @default.
• W2892032685 cites W2166306956 @default.
• W2892032685 cites W2180300108 @default.
• W2892032685 cites W2262047238 @default.
• W2892032685 cites W2281948879 @default.
• W2892032685 cites W2321397428 @default.
• W2892032685 cites W2324399464 @default.
• W2892032685 cites W2325539269 @default.
• W2892032685 cites W2326899644 @default.
• W2892032685 cites W2481955869 @default.
• W2892032685 cites W2483629101 @default.
• W2892032685 cites W2485896866 @default.
• W2892032685 cites W2491297661 @default.
• W2892032685 cites W2523991984 @default.
• W2892032685 cites W2949525672 @default.
• W2892032685 cites W2949887517 @default.
• W2892032685 cites W2949914287 @default.
• W2892032685 cites W2949941656 @default.
• W2892032685 cites W2950185812 @default.
• W2892032685 cites W2951544672 @default.
• W2892032685 cites W2951612914 @default.
• W2892032685 cites W2977261933 @default.
• W2892032685 cites W4205787807 @default.
• W2892032685 cites W4229806251 @default.
• W2892032685 cites W4239330670 @default.
• W2892032685 cites W4241995621 @default.
• W2892032685 cites W4245293663 @default.
• W2892032685 cites W4246139934 @default.
• W2892032685 cites W4250087728 @default.
• W2892032685 cites W4251691544 @default.
• W2892032685 cites W4254090090 @default.
• W2892032685 doi "https://doi.org/10.1002/chem.201804131" @default.
• W2892032685 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6391974" @default.
• W2892032685 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30203869" @default.
• W2892032685 hasPublicationYear "2018" @default.
• W2892032685 type Work @default.

• next