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• W2892045912 abstract "Selective Serotonin Reuptake Inhibitors (SSRIs) may have side effects, such as stiffness, tremors and altered tonic activity, as well as an increased risk of developing insulin resistance and diabetes mellitus. However, little is known about the structural, functional and metabolic changes of skeletal muscle after administration of SSRIs. The aim of this systematic review was to explore and discuss the effects of SSRIs on skeletal muscle properties described in human and rodent studies. A systematic search of PUBMED, SCOPUS, and WEB OF SCIENCE was performed. The inclusion criteria were intervention studies in humans and rodents that analysed the effects of SSRIs on skeletal muscle properties. The research found a total of six human studies, including two randomized controlled trials, one non-randomized controlled trial, one uncontrolled before-after study and two case reports, and six preclinical studies in rodents. Overall, the studies in humans and rodents showed altered electrical activity in skeletal muscle function, assessed through electromyography (EMG) and needle EMG in response to chronic treatment or local injection with SSRIs. In addition, rodent studies reported that SSRIs may exert effects on muscle weight, the number of myocytes and the cross-sectional area of skeletal muscle fibre. The results showed effects in energy metabolism associated with chronic SSRI use, reporting altered levels of glycogen synthase activity, acetyl-CoA carboxylase phosphorylation, citrate synthase activity, and protein kinase B Ser phosphorylation. Moreover, changes in insulin signalling and glucose uptake were documented. In this context, we concluded based on human and rodent studies that SSRIs affect electrical muscle activity, structural properties and energy metabolism in skeletal muscle tissue. However, these changes varied according to pre-existing metabolic and functional conditions in the rodents and humans." @default.
• W2892045912 created "2018-09-27" @default.
• W2892045912 creator A5005226053 @default.
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• W2892045912 date "2018-10-01" @default.
• W2892045912 modified "2023-09-23" @default.
• W2892045912 title "Selective serotonin reuptake inhibitors affect structure, function and metabolism of skeletal muscle: A systematic review" @default.
• W2892045912 cites W1515279996 @default.
• W2892045912 cites W1539272885 @default.
• W2892045912 cites W1591289976 @default.
• W2892045912 cites W1932150911 @default.
• W2892045912 cites W1964042817 @default.
• W2892045912 cites W1968652252 @default.
• W2892045912 cites W1973346625 @default.
• W2892045912 cites W1974033774 @default.
• W2892045912 cites W1974074028 @default.
• W2892045912 cites W1975108317 @default.
• W2892045912 cites W1975689471 @default.
• W2892045912 cites W1980100683 @default.
• W2892045912 cites W1982104904 @default.
• W2892045912 cites W1983734103 @default.
• W2892045912 cites W1985136513 @default.
• W2892045912 cites W1985828083 @default.
• W2892045912 cites W1994235619 @default.
• W2892045912 cites W2000232109 @default.
• W2892045912 cites W2005233160 @default.
• W2892045912 cites W2006155771 @default.
• W2892045912 cites W2008107458 @default.
• W2892045912 cites W2013256195 @default.
• W2892045912 cites W2019939591 @default.
• W2892045912 cites W2022474767 @default.
• W2892045912 cites W2023585901 @default.
• W2892045912 cites W2023673457 @default.
• W2892045912 cites W2024950964 @default.
• W2892045912 cites W2026410503 @default.
• W2892045912 cites W2028353138 @default.
• W2892045912 cites W2031280190 @default.
• W2892045912 cites W2031681863 @default.
• W2892045912 cites W2041650469 @default.
• W2892045912 cites W2042542409 @default.
• W2892045912 cites W2050746153 @default.
• W2892045912 cites W2058571677 @default.
• W2892045912 cites W2061574257 @default.
• W2892045912 cites W2063638540 @default.
• W2892045912 cites W2068991788 @default.
• W2892045912 cites W2071428537 @default.
• W2892045912 cites W2075031997 @default.
• W2892045912 cites W2077960715 @default.
• W2892045912 cites W2086476719 @default.
• W2892045912 cites W2086775351 @default.
• W2892045912 cites W2095253451 @default.
• W2892045912 cites W2096242757 @default.
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• W2892045912 cites W2099335027 @default.
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• W2892045912 cites W2126738264 @default.
• W2892045912 cites W2129633806 @default.
• W2892045912 cites W2129767627 @default.
• W2892045912 cites W2131845563 @default.
• W2892045912 cites W2135190897 @default.
• W2892045912 cites W2139677260 @default.
• W2892045912 cites W2152902331 @default.
• W2892045912 cites W2153038360 @default.
• W2892045912 cites W2154554143 @default.
• W2892045912 cites W2157126630 @default.
• W2892045912 cites W2164491574 @default.
• W2892045912 cites W2179764606 @default.
• W2892045912 cites W2238568958 @default.
• W2892045912 cites W2239620465 @default.
• W2892045912 cites W2284164129 @default.
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• W2892045912 cites W2287030368 @default.
• W2892045912 cites W2315088926 @default.
• W2892045912 cites W2407279452 @default.
• W2892045912 cites W2431575019 @default.
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• W2892045912 doi "https://doi.org/10.1016/j.phrs.2018.09.004" @default.
• W2892045912 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30196103" @default.
• W2892045912 hasPublicationYear "2018" @default.
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