FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2892055531> ?p ?o ?g. }

• W2892055531 endingPage "261" @default.
• W2892055531 startingPage "249" @default.
• W2892055531 abstract "Dabry's sturgeon (Acipenser dabryanus), as a living fossil, is considered a critically endangered aquatic animal in China. To date, the immune system of this species remains largely unknown, with limited available sequence information. In addition, increasing incidence of bacterial pathogenic diseases has been reported. Hence, the present study aimed to characterize comprehensively transcriptome profile of the head kidney from Dabry's sturgeon infected with Aeromonas hydrophila using Illumina platform. Over 42 million high-quality reads were obtained and de novo assembled into a final set of 195240 unique transcript fragments (unigenes), with an average length of 564 bp. Approximately 41702 unigenes were annotated in the NR NCBI database. Dabry's sturgeon unigenes had the highest number of hits with 14365 (34.45%) to Lepisosteus oculatus. The 195240 unigenes were assigned to three Gene Ontology (GO) categories: biological process, cellular component, and molecular function. Among them, 27770 unigenes were clustered into 26 Eukaryotic Orthologous Group (KOG) functional categories, and 36031 unigenes were mapped to 335 known Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways. After A. hydrophila administration, 1728 differentially expressed unigenes were identified, including 980 upregulated and 748 downregulated unigenes. Further KEGG enrichment analysis of these unigenes identified 16 immune-related pathways, including the Toll-like receptor signaling pathway, chemokine signaling pathway, complement and coagulation pathway, RIG-I-like receptor signaling pathway, and NOD-like receptor signaling pathway. 20 DEGs were selected and their expression patterns are largely consistent with the transcriptome profile analysis, which clearly validated the reliability of the DEGs in transcriptome analysis. This work revealed novel gene expression patterns of Dabry's sturgeon host defense and contributes to a better understanding of the immune system and defense mechanisms of Dabry's sturgeon in response to bacterial infection. The results provide valuable references for studies in sturgeons that lack complete genomic sequences, and could also be helpful for the analyzing evolution among cartilaginous and teleost fish." @default.
• W2892055531 created "2018-09-27" @default.
• W2892055531 creator A5002503718 @default.
• W2892055531 creator A5025309622 @default.
• W2892055531 creator A5033545758 @default.
• W2892055531 creator A5040540716 @default.
• W2892055531 creator A5043158659 @default.
• W2892055531 creator A5058233558 @default.
• W2892055531 creator A5075434127 @default.
• W2892055531 creator A5078252124 @default.
• W2892055531 creator A5084640811 @default.
• W2892055531 date "2018-12-01" @default.
• W2892055531 modified "2023-10-06" @default.
• W2892055531 title "Transcriptome analysis of the critically endangered Dabry's sturgeon (Acipenser dabryanus) head kidney response to Aeromonas hydrophila" @default.
• W2892055531 cites W1182348828 @default.
• W2892055531 cites W1505229526 @default.
• W2892055531 cites W1580677244 @default.
• W2892055531 cites W1966152644 @default.
• W2892055531 cites W1972367387 @default.
• W2892055531 cites W1973101085 @default.
• W2892055531 cites W1973646620 @default.
• W2892055531 cites W1975389920 @default.
• W2892055531 cites W1979446719 @default.
• W2892055531 cites W1999574084 @default.
• W2892055531 cites W2002200743 @default.
• W2892055531 cites W2004622806 @default.
• W2892055531 cites W2011051379 @default.
• W2892055531 cites W2011653766 @default.
• W2892055531 cites W2011657487 @default.
• W2892055531 cites W2017267708 @default.
• W2892055531 cites W2025551088 @default.
• W2892055531 cites W2030313939 @default.
• W2892055531 cites W2036209716 @default.
• W2892055531 cites W2040112602 @default.
• W2892055531 cites W2041299250 @default.
• W2892055531 cites W2042433863 @default.
• W2892055531 cites W2046665298 @default.
• W2892055531 cites W2051033007 @default.
• W2892055531 cites W2051565439 @default.
• W2892055531 cites W2059848353 @default.
• W2892055531 cites W2061881258 @default.
• W2892055531 cites W2063160102 @default.
• W2892055531 cites W2071760290 @default.
• W2892055531 cites W2077474284 @default.
• W2892055531 cites W2082476225 @default.
• W2892055531 cites W2086617945 @default.
• W2892055531 cites W2089380674 @default.
• W2892055531 cites W2092108055 @default.
• W2892055531 cites W2095401221 @default.
• W2892055531 cites W2101972919 @default.
• W2892055531 cites W2103017472 @default.
• W2892055531 cites W2110111295 @default.
• W2892055531 cites W2110256992 @default.
• W2892055531 cites W2116459105 @default.
• W2892055531 cites W2119306878 @default.
• W2892055531 cites W2130916990 @default.
• W2892055531 cites W2131271579 @default.
• W2892055531 cites W2131459193 @default.
• W2892055531 cites W2133579817 @default.
• W2892055531 cites W2133790733 @default.
• W2892055531 cites W2145092950 @default.
• W2892055531 cites W2145532569 @default.
• W2892055531 cites W2151713498 @default.
• W2892055531 cites W2155606054 @default.
• W2892055531 cites W2156770662 @default.
• W2892055531 cites W2164154943 @default.
• W2892055531 cites W2207695357 @default.
• W2892055531 cites W2293662776 @default.
• W2892055531 cites W2400245958 @default.
• W2892055531 cites W2462956003 @default.
• W2892055531 cites W2548927534 @default.
• W2892055531 cites W2592727111 @default.
• W2892055531 cites W2608031050 @default.
• W2892055531 cites W2611710183 @default.
• W2892055531 cites W2769154139 @default.
• W2892055531 cites W2793230576 @default.
• W2892055531 cites W2803475256 @default.
• W2892055531 cites W4232378514 @default.
• W2892055531 doi "https://doi.org/10.1016/j.fsi.2018.09.044" @default.
• W2892055531 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30219387" @default.
• W2892055531 hasPublicationYear "2018" @default.
• W2892055531 type Work @default.
• W2892055531 sameAs 2892055531 @default.
• W2892055531 citedByCount "30" @default.
• W2892055531 countsByYear W28920555312019 @default.
• W2892055531 countsByYear W28920555312020 @default.
• W2892055531 countsByYear W28920555312021 @default.
• W2892055531 countsByYear W28920555312022 @default.
• W2892055531 countsByYear W28920555312023 @default.
• W2892055531 crossrefType "journal-article" @default.
• W2892055531 hasAuthorship W2892055531A5002503718 @default.
• W2892055531 hasAuthorship W2892055531A5025309622 @default.
• W2892055531 hasAuthorship W2892055531A5033545758 @default.
• W2892055531 hasAuthorship W2892055531A5040540716 @default.
• W2892055531 hasAuthorship W2892055531A5043158659 @default.
• W2892055531 hasAuthorship W2892055531A5058233558 @default.
• W2892055531 hasAuthorship W2892055531A5075434127 @default.
• W2892055531 hasAuthorship W2892055531A5078252124 @default.

• next