FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2892056685> ?p ?o ?g. }

• W2892056685 endingPage "569" @default.
• W2892056685 startingPage "568" @default.
• W2892056685 abstract "Termination of pregnancy for fetal anomaly is legal in the UK with no upper limit, if two doctors, in good faith, agree “there is a substantial risk that if the child were born it would suffer from such physical or mental abnormalities as to be seriously handicapped”. This is Clause E of the Human Fertlisation and Embryology Act. The most commonly sighted Clause is C, which states “the pregnancy has not exceeded its twenty-fourth week and that the continuance of the pregnancy would involve risk, greater than if the pregnancy were terminated, of injury to the physical or mental health of the pregnant woman”. This study aimed to investigate health professionals’ views on gestational age and acceptable termination of pregnancy for fetal anomaly (TOPFA).We undertook a questionnaire survey of UK health professionals working in fetal medicine, obstetrics and gynaecology and neonatology. A study pack consisting of a self-completion questionnaire, an invitation letter, participant information sheet, and a stamped addressed return envelope, were sent to health professionals. We used four fetal anomalies as case study examples in the questionnaire: isolated cleft lip, hypoplastic left heart, spina bifida and trisomy 21. These anomalies were chosen as they differed in terms of the type of anomaly, the type of impairment, and the perceived severity.Forty-one study packs were returned. For anomalies deemed less serious, later gestational ages were an important consideration when deciding acceptable TOPFA. The prognosis of an anomaly was considered an important factor in deciding whether a TOPFA was acceptable alongside gestational age. Clause C of the current UK legislation, which allows a legal termination prior to 24 weeks gestational age if continuing with the pregnancy would impact the mental health of the mother, was deemed a reasonable option for termination when parents are requesting a TOPFA. For each case study example, health professionals responded that TOPFA at ‘25 weeks and over’ was acceptable (cleft lip n = 1; hypoplastic left heart n = 19; spina bifida n = 13 and Trisomy 21 n = 10). Professionals also distinguished between their personal and professional views.These findings offer new insight into how gestational age considerations influence professionals’ conceptualisation of acceptable TOPFA." @default.
• W2892056685 created "2018-09-27" @default.
• W2892056685 creator A5019980600 @default.
• W2892056685 creator A5046761393 @default.
• W2892056685 creator A5057876837 @default.
• W2892056685 creator A5086996566 @default.
• W2892056685 creator A5088402711 @default.
• W2892056685 date "2018-09-01" @default.
• W2892056685 modified "2023-10-16" @default.
• W2892056685 title "Clinically relevant copy number variants in children with congenital anomalies" @default.
• W2892056685 doi "https://doi.org/10.1016/j.ejmg.2018.06.061" @default.
• W2892056685 hasPublicationYear "2018" @default.
• W2892056685 type Work @default.
• W2892056685 sameAs 2892056685 @default.
• W2892056685 citedByCount "0" @default.
• W2892056685 crossrefType "journal-article" @default.
• W2892056685 hasAuthorship W2892056685A5019980600 @default.
• W2892056685 hasAuthorship W2892056685A5046761393 @default.
• W2892056685 hasAuthorship W2892056685A5057876837 @default.
• W2892056685 hasAuthorship W2892056685A5086996566 @default.
• W2892056685 hasAuthorship W2892056685A5088402711 @default.
• W2892056685 hasConcept C118552586 @default.
• W2892056685 hasConcept C131872663 @default.
• W2892056685 hasConcept C134362201 @default.
• W2892056685 hasConcept C15744967 @default.
• W2892056685 hasConcept C187212893 @default.
• W2892056685 hasConcept C2776229224 @default.
• W2892056685 hasConcept C2778376644 @default.
• W2892056685 hasConcept C2779234561 @default.
• W2892056685 hasConcept C512399662 @default.
• W2892056685 hasConcept C54355233 @default.
• W2892056685 hasConcept C71924100 @default.
• W2892056685 hasConcept C86803240 @default.
• W2892056685 hasConceptScore W2892056685C118552586 @default.
• W2892056685 hasConceptScore W2892056685C131872663 @default.
• W2892056685 hasConceptScore W2892056685C134362201 @default.
• W2892056685 hasConceptScore W2892056685C15744967 @default.
• W2892056685 hasConceptScore W2892056685C187212893 @default.
• W2892056685 hasConceptScore W2892056685C2776229224 @default.
• W2892056685 hasConceptScore W2892056685C2778376644 @default.
• W2892056685 hasConceptScore W2892056685C2779234561 @default.
• W2892056685 hasConceptScore W2892056685C512399662 @default.
• W2892056685 hasConceptScore W2892056685C54355233 @default.
• W2892056685 hasConceptScore W2892056685C71924100 @default.
• W2892056685 hasConceptScore W2892056685C86803240 @default.
• W2892056685 hasIssue "9" @default.
• W2892056685 hasLocation W28920566851 @default.
• W2892056685 hasOpenAccess W2892056685 @default.
• W2892056685 hasPrimaryLocation W28920566851 @default.
• W2892056685 hasRelatedWork W2002867793 @default.
• W2892056685 hasRelatedWork W2017565203 @default.
• W2892056685 hasRelatedWork W2052494798 @default.
• W2892056685 hasRelatedWork W2283375914 @default.
• W2892056685 hasRelatedWork W2333891256 @default.
• W2892056685 hasRelatedWork W2419575786 @default.
• W2892056685 hasRelatedWork W2502977617 @default.
• W2892056685 hasRelatedWork W2891700714 @default.
• W2892056685 hasRelatedWork W3194350171 @default.
• W2892056685 hasRelatedWork W2735401012 @default.
• W2892056685 hasVolume "61" @default.
• W2892056685 isParatext "false" @default.
• W2892056685 isRetracted "false" @default.
• W2892056685 magId "2892056685" @default.
• W2892056685 workType "article" @default.