Matches in SemOpenAlex for { <https://semopenalex.org/work/W2892059265> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2892059265 endingPage "116" @default.
- W2892059265 startingPage "108" @default.
- W2892059265 abstract "Acute lymphoblastic leukemia is the most common childhood cancer, yet surprisingly, very few studies have reported the treatment outcomes and the relapse rate of patients from low/middle-income countries.This study was a 5-year retrospective cohort study. It was conducted at Oncology Center of Mansoura University in Egypt and aimed to estimate the treatment outcomes and the relapse rates of newly diagnosed acute lymphoblastic leukemia in children.Two hundred children suffering from acute lymphoblastic leukemia were studied; forty-six patients (23%) died during induction and most of those deaths were related to infection. Forty-one patients (27%) relapsed out of the 152 patients who achieved complete remission. The most common site of relapse was the bone marrow, followed by the isolated central nervous system, 53.7% and 31.7%, respectively. Seventy-eight percent of relapses occurred very early/early rather than later. The majority of relapse patients' deaths were related to infection and disease progression. The 5-year overall survival rate for patients was 63.1% (82.1% for non-relapsed compared to 36.6% for relapsed patients).There was a high incidence of induction deaths related to infection and high percentages of very early/early relapses, with high mortalities and low 5-year overall survival rates. These findings suggest the urgent need for modification of chemotherapy regimens to be suitable for the local conditions, including implementation of supportive care and infection control policies. There is also a requirement for antimicrobial prophylaxis during induction period combined with the necessary increase in government healthcare spending to improve the survival of acute lymphoblastic leukemia in Egyptian children." @default.
- W2892059265 created "2018-09-27" @default.
- W2892059265 creator A5046759299 @default.
- W2892059265 creator A5062332652 @default.
- W2892059265 creator A5067383635 @default.
- W2892059265 creator A5091037586 @default.
- W2892059265 date "2020-01-01" @default.
- W2892059265 modified "2023-10-01" @default.
- W2892059265 title "Treatment outcomes of children with acute lymphoblastic leukemia in a middle-income developing country: high mortalities, early relapses, and poor survival" @default.
- W2892059265 cites W1498271295 @default.
- W2892059265 cites W1572741394 @default.
- W2892059265 cites W1778891964 @default.
- W2892059265 cites W1856197384 @default.
- W2892059265 cites W1971541045 @default.
- W2892059265 cites W1983930052 @default.
- W2892059265 cites W2004754777 @default.
- W2892059265 cites W2007437787 @default.
- W2892059265 cites W2023942693 @default.
- W2892059265 cites W2036438073 @default.
- W2892059265 cites W2037522752 @default.
- W2892059265 cites W2041123215 @default.
- W2892059265 cites W2051227774 @default.
- W2892059265 cites W2068936243 @default.
- W2892059265 cites W2074181164 @default.
- W2892059265 cites W2086930388 @default.
- W2892059265 cites W2089807299 @default.
- W2892059265 cites W2111042804 @default.
- W2892059265 cites W2118719559 @default.
- W2892059265 cites W2129213695 @default.
- W2892059265 cites W2163398618 @default.
- W2892059265 cites W2165609679 @default.
- W2892059265 cites W2319537152 @default.
- W2892059265 cites W2567576867 @default.
- W2892059265 cites W2782376865 @default.
- W2892059265 cites W2401014947 @default.
- W2892059265 doi "https://doi.org/10.1016/j.jped.2018.07.013" @default.
- W2892059265 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30240631" @default.
- W2892059265 hasPublicationYear "2020" @default.
- W2892059265 type Work @default.
- W2892059265 sameAs 2892059265 @default.
- W2892059265 citedByCount "22" @default.
- W2892059265 countsByYear W28920592652019 @default.
- W2892059265 countsByYear W28920592652020 @default.
- W2892059265 countsByYear W28920592652021 @default.
- W2892059265 countsByYear W28920592652022 @default.
- W2892059265 countsByYear W28920592652023 @default.
- W2892059265 crossrefType "journal-article" @default.
- W2892059265 hasAuthorship W2892059265A5046759299 @default.
- W2892059265 hasAuthorship W2892059265A5062332652 @default.
- W2892059265 hasAuthorship W2892059265A5067383635 @default.
- W2892059265 hasAuthorship W2892059265A5091037586 @default.
- W2892059265 hasBestOaLocation W28920592651 @default.
- W2892059265 hasConcept C120665830 @default.
- W2892059265 hasConcept C121332964 @default.
- W2892059265 hasConcept C121608353 @default.
- W2892059265 hasConcept C126322002 @default.
- W2892059265 hasConcept C167135981 @default.
- W2892059265 hasConcept C187212893 @default.
- W2892059265 hasConcept C2776863199 @default.
- W2892059265 hasConcept C2778461978 @default.
- W2892059265 hasConcept C2779134260 @default.
- W2892059265 hasConcept C61511704 @default.
- W2892059265 hasConcept C71924100 @default.
- W2892059265 hasConceptScore W2892059265C120665830 @default.
- W2892059265 hasConceptScore W2892059265C121332964 @default.
- W2892059265 hasConceptScore W2892059265C121608353 @default.
- W2892059265 hasConceptScore W2892059265C126322002 @default.
- W2892059265 hasConceptScore W2892059265C167135981 @default.
- W2892059265 hasConceptScore W2892059265C187212893 @default.
- W2892059265 hasConceptScore W2892059265C2776863199 @default.
- W2892059265 hasConceptScore W2892059265C2778461978 @default.
- W2892059265 hasConceptScore W2892059265C2779134260 @default.
- W2892059265 hasConceptScore W2892059265C61511704 @default.
- W2892059265 hasConceptScore W2892059265C71924100 @default.
- W2892059265 hasIssue "1" @default.
- W2892059265 hasLocation W28920592651 @default.
- W2892059265 hasLocation W28920592652 @default.
- W2892059265 hasLocation W28920592653 @default.
- W2892059265 hasLocation W28920592654 @default.
- W2892059265 hasLocation W28920592655 @default.
- W2892059265 hasOpenAccess W2892059265 @default.
- W2892059265 hasPrimaryLocation W28920592651 @default.
- W2892059265 hasRelatedWork W1965705219 @default.
- W2892059265 hasRelatedWork W1969388105 @default.
- W2892059265 hasRelatedWork W2055132182 @default.
- W2892059265 hasRelatedWork W2077163773 @default.
- W2892059265 hasRelatedWork W2097406911 @default.
- W2892059265 hasRelatedWork W2265868850 @default.
- W2892059265 hasRelatedWork W2275480158 @default.
- W2892059265 hasRelatedWork W2407631157 @default.
- W2892059265 hasRelatedWork W4238089809 @default.
- W2892059265 hasRelatedWork W43178823 @default.
- W2892059265 hasVolume "96" @default.
- W2892059265 isParatext "false" @default.
- W2892059265 isRetracted "false" @default.
- W2892059265 magId "2892059265" @default.
- W2892059265 workType "article" @default.