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• W2892059973 abstract "Copper (Cu) and zinc (Zn) deficiency may cause poor weight gain, hematological changes, and immune failure in extensive beef cattle breeding systems. Diagnosis of the deficiency is based on plasma Cu and Zn concentrations; however, there are discrepancies regarding data interpretation. Here, plasma Cu and Zn concentrations are discussed as risk markers. We evaluated the effect of parenteral Cu and Zn supplementation on their plasma concentrations, weight gain, hematological parameters, and antibody titers to bovine herpes virus 1 (BoHV-1). Pre-weaning calves (n = 40; 99 ± 8 kg bw) from a typical breeding area of Argentina with background Cu and Zn deficiency were used. They were assigned to two homogeneous groups in a completely randomized design. Calves were subcutaneously injected with 0.3 mg/kg Cu and 1 mg/kg Zn (supplemented group), or saline solution (control), every 40 days during 120 days. Plasma Cu and Zn concentrations, hematological parameters, and weight were recorded. On days 40 and 80 of the trial, calves were vaccinated with inactivated BoHV-1. Antibody immune response was measured on days 80 and 120. Data were analyzed with a mixed model for repeated measures over time. Before treatment, plasma Cu was low and Zn was adequate in both groups. After treatment, plasma Cu increased and remained within a normal range, whereas plasma Zn remained constant. Supplemented animals had higher weight gain (p < 0.01); higher hematocrit, mean corpuscular volume, and mean corpuscular hemoglobin levels (p < 0.05); and higher immune response to BoHV-1 (p < 0.05). Our results suggest that Cu and Zn supplementation improved daily weight gain and the immune response of pre-weaning calves." @default.
• W2892059973 created "2018-09-27" @default.
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• W2892059973 date "2018-09-08" @default.
• W2892059973 modified "2023-10-12" @default.
• W2892059973 title "Effect of Injectable Copper and Zinc Supplementation on Weight, Hematological Parameters, and Immune Response in Pre-weaning Beef Calves" @default.
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• W2892059973 doi "https://doi.org/10.1007/s12011-018-1493-9" @default.
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• W2892059973 hasPublicationYear "2018" @default.
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