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• W2892070821 abstract "Brain deformation (or brain shift) during neurosurgical procedures such as tumor resection has a significant impact on the accuracy of neuronavigation systems. Compensating for this deformation during surgery is essential for effective guidance. In this paper, we propose a method for brain shift compensation based on registration of vessel centerlines derived from preoperative C-Arm cone beam CT (CBCT) images, to intraoperative ones. A hybrid mixture model (HdMM)-based non-rigid registration approach was formulated wherein, Student’s t and Watson distributions were combined to model positions and centerline orientations of cerebral vasculature, respectively. Following registration of the preoperative vessel centerlines to its intraoperative counterparts, B-spline interpolation was used to generate a dense deformation field and warp the preoperative image to each intraoperative image acquired. Registration accuracy was evaluated using both synthetic and clinical data. The former comprised CBCT images, acquired using a deformable anthropomorphic brain phantom. The latter meanwhile, consisted of four 3D digital subtraction angiography (DSA) images of one patient, acquired before, during and after surgical tumor resection. HdMM consistently outperformed a state-of-the-art point matching method, coherent point drift (CPD), resulting in significantly lower registration errors. For clinical data, the registration error was reduced from 3.73 mm using CPD to 1.55 mm using the proposed method." @default.
• W2892070821 created "2018-09-27" @default.
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• W2892070821 date "2018-01-01" @default.
• W2892070821 modified "2023-10-02" @default.
• W2892070821 title "Intraoperative Brain Shift Compensation Using a Hybrid Mixture Model" @default.
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• W2892070821 doi "https://doi.org/10.1007/978-3-030-00937-3_14" @default.
• W2892070821 hasPublicationYear "2018" @default.
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