FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2892071912> ?p ?o ?g. }

• W2892071912 endingPage "217" @default.
• W2892071912 startingPage "207" @default.
• W2892071912 abstract "Abstract Background Doxorubicin (DOX) is a common chemotherapeutic drug. However, it causes cardiomyopathy which reduces its clinical use in human cancer therapy. Objective The purpose of our study was to assess the cardioprotective effect of hesperidin (HSP) and vitamin E (VIT.E) against DOX-induced cardiomyopathy. Material and methods Seventy rats were allocated into seven groups: control, HSP (50 mg/kg, orally), VIT.E (100 mg/kg orally), DOX [4 mg/kg, intraperitoneally (i.p.)], DOX+HSP, DOX+VIT.E and DOX+HSP+VIT.E. Results Our findings showed that serum lactate dehydrogenase (LDH), creatine kinase (CK), myeloperoxidase (MPO), cardiac catalase and caspase activities as well as cardiac malondialdehyde (MDA) and serum nitric oxide (NO) concentrations were reduced DOX+HSP or DOX+VIT.E or DOX+VIT.E+HSP groups compared to DOX group. Whereas, cardiac reduced glutathione (GSH) level, serum arylesterase, and paraoxonase activities were higher in rats injected with DOX and administrated with HSP and VIT.E than that of rats injected with DOX only. Cardiac histopathology of DOX group showed some changes that were improved during administration with HSP and VIT.E. Conclusion HSP and VIT.E possess a protective effect against DOX-induced cardiomyopathy via inhibiting oxidative stress, inflammation, and apoptosis." @default.
• W2892071912 created "2018-09-27" @default.
• W2892071912 creator A5029770014 @default.
• W2892071912 creator A5034339408 @default.
• W2892071912 creator A5072349207 @default.
• W2892071912 date "2018-09-05" @default.
• W2892071912 modified "2023-09-30" @default.
• W2892071912 title "Ameliorating oxidative stress and inflammation by Hesperidin and vitamin E in doxorubicin induced cardiomyopathy" @default.
• W2892071912 cites W1481677483 @default.
• W2892071912 cites W1575245978 @default.
• W2892071912 cites W1775749144 @default.
• W2892071912 cites W1964447535 @default.
• W2892071912 cites W1971644907 @default.
• W2892071912 cites W1974784131 @default.
• W2892071912 cites W1976658323 @default.
• W2892071912 cites W1986490936 @default.
• W2892071912 cites W1992380626 @default.
• W2892071912 cites W1992832943 @default.
• W2892071912 cites W1997047765 @default.
• W2892071912 cites W2003572998 @default.
• W2892071912 cites W2004173452 @default.
• W2892071912 cites W2006370393 @default.
• W2892071912 cites W2012972697 @default.
• W2892071912 cites W2041774799 @default.
• W2892071912 cites W2042395462 @default.
• W2892071912 cites W2046703464 @default.
• W2892071912 cites W2051092344 @default.
• W2892071912 cites W2057983519 @default.
• W2892071912 cites W2068399996 @default.
• W2892071912 cites W2081145901 @default.
• W2892071912 cites W2084304742 @default.
• W2892071912 cites W2088720985 @default.
• W2892071912 cites W2117552900 @default.
• W2892071912 cites W2127284954 @default.
• W2892071912 cites W2144567633 @default.
• W2892071912 cites W2419199177 @default.
• W2892071912 cites W2526655986 @default.
• W2892071912 cites W2567537481 @default.
• W2892071912 cites W2597308177 @default.
• W2892071912 cites W2794216387 @default.
• W2892071912 doi "https://doi.org/10.1515/tjb-2018-0156" @default.
• W2892071912 hasPublicationYear "2018" @default.
• W2892071912 type Work @default.
• W2892071912 sameAs 2892071912 @default.
• W2892071912 citedByCount "9" @default.
• W2892071912 countsByYear W28920719122020 @default.
• W2892071912 countsByYear W28920719122021 @default.
• W2892071912 countsByYear W28920719122022 @default.
• W2892071912 countsByYear W28920719122023 @default.
• W2892071912 crossrefType "journal-article" @default.
• W2892071912 hasAuthorship W2892071912A5029770014 @default.
• W2892071912 hasAuthorship W2892071912A5034339408 @default.
• W2892071912 hasAuthorship W2892071912A5072349207 @default.
• W2892071912 hasBestOaLocation W28920719121 @default.
• W2892071912 hasConcept C126322002 @default.
• W2892071912 hasConcept C134018914 @default.
• W2892071912 hasConcept C142724271 @default.
• W2892071912 hasConcept C181199279 @default.
• W2892071912 hasConcept C185592680 @default.
• W2892071912 hasConcept C203565725 @default.
• W2892071912 hasConcept C204787440 @default.
• W2892071912 hasConcept C2776128092 @default.
• W2892071912 hasConcept C2776151105 @default.
• W2892071912 hasConcept C2776694085 @default.
• W2892071912 hasConcept C2776914184 @default.
• W2892071912 hasConcept C2777318727 @default.
• W2892071912 hasConcept C2777551382 @default.
• W2892071912 hasConcept C2778004101 @default.
• W2892071912 hasConcept C2778401633 @default.
• W2892071912 hasConcept C2781303535 @default.
• W2892071912 hasConcept C538909803 @default.
• W2892071912 hasConcept C55493867 @default.
• W2892071912 hasConcept C71924100 @default.
• W2892071912 hasConcept C98274493 @default.
• W2892071912 hasConceptScore W2892071912C126322002 @default.
• W2892071912 hasConceptScore W2892071912C134018914 @default.
• W2892071912 hasConceptScore W2892071912C142724271 @default.
• W2892071912 hasConceptScore W2892071912C181199279 @default.
• W2892071912 hasConceptScore W2892071912C185592680 @default.
• W2892071912 hasConceptScore W2892071912C203565725 @default.
• W2892071912 hasConceptScore W2892071912C204787440 @default.
• W2892071912 hasConceptScore W2892071912C2776128092 @default.
• W2892071912 hasConceptScore W2892071912C2776151105 @default.
• W2892071912 hasConceptScore W2892071912C2776694085 @default.
• W2892071912 hasConceptScore W2892071912C2776914184 @default.
• W2892071912 hasConceptScore W2892071912C2777318727 @default.
• W2892071912 hasConceptScore W2892071912C2777551382 @default.
• W2892071912 hasConceptScore W2892071912C2778004101 @default.
• W2892071912 hasConceptScore W2892071912C2778401633 @default.
• W2892071912 hasConceptScore W2892071912C2781303535 @default.
• W2892071912 hasConceptScore W2892071912C538909803 @default.
• W2892071912 hasConceptScore W2892071912C55493867 @default.
• W2892071912 hasConceptScore W2892071912C71924100 @default.
• W2892071912 hasConceptScore W2892071912C98274493 @default.
• W2892071912 hasIssue "2" @default.
• W2892071912 hasLocation W28920719121 @default.
• W2892071912 hasOpenAccess W2892071912 @default.
• W2892071912 hasPrimaryLocation W28920719121 @default.

• next