FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2892081514> ?p ?o ?g. }

• W2892081514 abstract "Psychological stress has been suggested to be relevant to the pathogenesis of neurodegenerative disorders, possibly via the generation of oxygen free radicals. We therefore sought to determine whether people with amyotrophic lateral sclerosis (ALS) had been subjected to more potentially stressful life events or occupations than controls, and whether they had differences in resilience or trait anxiety that would moderate their responses to these stressors. An online anonymous multilingual questionnaire was used to collect data on significant life events from people with and without ALS, using items from a modified Social Readjustment Rating Scale and from self-described significant events, which were combined to create a Life Events Inventory. Inventory scores were subdivided into 0-20 years and 21-40 years age ranges, and for the preceding 2, 5 and 10 years. Respondents also rated levels of stress experienced during different occupations. Resilience was measured using the Connor-Davidson Resilience Scale, and trait anxiety with a modified Geriatric Anxiety Inventory. Scores were compared using nonparametric statistics. Data from 400 ALS (251 male, 149 female) and 450 control (130 male, 320 female) respondents aged 40 years and over showed that Life Events Inventory scores were similar in male ALS respondents and controls, but lower in female ALS respondents than female controls for the preceding 5-year and 10-year periods. Occupational stress did not differ between ALS respondents and controls. Both male and female ALS respondents had higher resilience scores than controls. Anxiety scores did not differ between ALS and control groups. In conclusion, people with ALS reported no raised levels of potentially stressful premorbid life events or occupational stress, and did not have reduced levels of resilience, or increased levels of anxiety, that would augment the deleterious effects of stressors. On the contrary, ALS respondents had higher resilience than controls, though this conclusion relies on ALS respondents recalling their premorbid status. These results do not support the hypothesis that psychological stress from significant life events or occupational stress plays a role in the pathogenesis of ALS." @default.
• W2892081514 created "2018-09-27" @default.
• W2892081514 creator A5011807762 @default.
• W2892081514 creator A5027819375 @default.
• W2892081514 creator A5048648105 @default.
• W2892081514 date "2018-09-21" @default.
• W2892081514 modified "2023-09-25" @default.
• W2892081514 title "Is psychological stress a predisposing factor for amyotrophic lateral sclerosis (ALS)? An online international case-control study of premorbid life events, occupational stress, resilience and anxiety" @default.
• W2892081514 cites W103404623 @default.
• W2892081514 cites W1444780264 @default.
• W2892081514 cites W1789457561 @default.
• W2892081514 cites W1803186607 @default.
• W2892081514 cites W1987388972 @default.
• W2892081514 cites W1995163274 @default.
• W2892081514 cites W1999941359 @default.
• W2892081514 cites W2007336957 @default.
• W2892081514 cites W2007550692 @default.
• W2892081514 cites W2013309206 @default.
• W2892081514 cites W2043830713 @default.
• W2892081514 cites W2084393171 @default.
• W2892081514 cites W2099365033 @default.
• W2892081514 cites W2108593116 @default.
• W2892081514 cites W2111629688 @default.
• W2892081514 cites W2112393842 @default.
• W2892081514 cites W2116810060 @default.
• W2892081514 cites W2118185372 @default.
• W2892081514 cites W2120449849 @default.
• W2892081514 cites W2130198046 @default.
• W2892081514 cites W2156824222 @default.
• W2892081514 cites W2161290803 @default.
• W2892081514 cites W2166499769 @default.
• W2892081514 cites W2166893354 @default.
• W2892081514 cites W2170180533 @default.
• W2892081514 cites W2333221561 @default.
• W2892081514 cites W2336430914 @default.
• W2892081514 cites W2508028826 @default.
• W2892081514 cites W2525501670 @default.
• W2892081514 cites W2556521730 @default.
• W2892081514 cites W2594803277 @default.
• W2892081514 cites W2744573777 @default.
• W2892081514 cites W2791480041 @default.
• W2892081514 cites W2794181230 @default.
• W2892081514 cites W2796271019 @default.
• W2892081514 cites W4210998205 @default.
• W2892081514 cites W4211093919 @default.
• W2892081514 cites W4239301040 @default.
• W2892081514 cites W1919166983 @default.
• W2892081514 doi "https://doi.org/10.1371/journal.pone.0204424" @default.
• W2892081514 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6150536" @default.
• W2892081514 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30240431" @default.
• W2892081514 hasPublicationYear "2018" @default.
• W2892081514 type Work @default.
• W2892081514 sameAs 2892081514 @default.
• W2892081514 citedByCount "7" @default.
• W2892081514 countsByYear W28920815142020 @default.
• W2892081514 countsByYear W28920815142021 @default.
• W2892081514 countsByYear W28920815142022 @default.
• W2892081514 crossrefType "journal-article" @default.
• W2892081514 hasAuthorship W2892081514A5011807762 @default.
• W2892081514 hasAuthorship W2892081514A5027819375 @default.
• W2892081514 hasAuthorship W2892081514A5048648105 @default.
• W2892081514 hasBestOaLocation W28920815141 @default.
• W2892081514 hasConcept C118552586 @default.
• W2892081514 hasConcept C125370674 @default.
• W2892081514 hasConcept C126322002 @default.
• W2892081514 hasConcept C137176749 @default.
• W2892081514 hasConcept C15744967 @default.
• W2892081514 hasConcept C2779134260 @default.
• W2892081514 hasConcept C2780596555 @default.
• W2892081514 hasConcept C542102704 @default.
• W2892081514 hasConcept C558461103 @default.
• W2892081514 hasConcept C70410870 @default.
• W2892081514 hasConcept C71924100 @default.
• W2892081514 hasConcept C74909509 @default.
• W2892081514 hasConceptScore W2892081514C118552586 @default.
• W2892081514 hasConceptScore W2892081514C125370674 @default.
• W2892081514 hasConceptScore W2892081514C126322002 @default.
• W2892081514 hasConceptScore W2892081514C137176749 @default.
• W2892081514 hasConceptScore W2892081514C15744967 @default.
• W2892081514 hasConceptScore W2892081514C2779134260 @default.
• W2892081514 hasConceptScore W2892081514C2780596555 @default.
• W2892081514 hasConceptScore W2892081514C542102704 @default.
• W2892081514 hasConceptScore W2892081514C558461103 @default.
• W2892081514 hasConceptScore W2892081514C70410870 @default.
• W2892081514 hasConceptScore W2892081514C71924100 @default.
• W2892081514 hasConceptScore W2892081514C74909509 @default.
• W2892081514 hasLocation W28920815141 @default.
• W2892081514 hasLocation W28920815142 @default.
• W2892081514 hasLocation W28920815143 @default.
• W2892081514 hasLocation W28920815144 @default.
• W2892081514 hasLocation W28920815145 @default.
• W2892081514 hasOpenAccess W2892081514 @default.
• W2892081514 hasPrimaryLocation W28920815141 @default.
• W2892081514 hasRelatedWork W2007942589 @default.
• W2892081514 hasRelatedWork W2594924483 @default.
• W2892081514 hasRelatedWork W2889500740 @default.
• W2892081514 hasRelatedWork W3046312479 @default.
• W2892081514 hasRelatedWork W3152805252 @default.
• W2892081514 hasRelatedWork W3155719720 @default.
• W2892081514 hasRelatedWork W4200293517 @default.

• next