FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2892133602> ?p ?o ?g. }

• W2892133602 abstract "Osteosarcoma is among the most frequently occurring bone tumors in infants and teenagers. However, despite its widespread prevalence, no effective diagnostic and prognostic biomarkers for osteosarcoma are known. Macrophage inhibitory cytokine 1 (MIC-1) has been considered a promising biological marker of various tumor types. However, the possible role of circulating MIC-1 as a screening biomarker for osteosarcoma remains to be elucidated. The present study evaluated the circulating levels of MIC-1 in patients with osteosarcoma with the aim of elucidating its effect on the diagnosis and prognosis of this specific tumor. The circulating levels of MIC-1 were measured via an enzyme-linked immunosorbent assay in 300 individuals, including 100 patients with osteosarcoma, 100 patients with benign bone tumors, and 100 healthy subjects, and its correlation with clinicopathological characteristics was then evaluated. Various analyses were performed to determine its utility in diagnosis and prognosis. The levels of circulating MIC-1 were increased considerably in patients with osteosarcoma. The patients bearing larger tumors, those with distant metastases, and those with later-stage tumors had relatively higher levels of MIC-1. According to the multivariate logistic regression analysis, a high level of circulating MIC-1 was an independent variable for distant metastases. Receiver operating characteristic analysis revealed MIC-1 as a possible biological marker for distinguishing patients from healthy controls. Patients with osteosarcoma with higher levels of MIC-1 had relatively higher risk of mortality. Furthermore, multivariate data analysis on general survival rate revealed that a high level of circulating MIC-1 was a prognostic indicator of osteosarcoma. These findings suggest that an elevated level of circulating MIC-1 is a novel potential diagnostic and prognostic biomarker for osteosarcoma." @default.
• W2892133602 created "2018-09-27" @default.
• W2892133602 creator A5012611812 @default.
• W2892133602 creator A5033763955 @default.
• W2892133602 creator A5054310694 @default.
• W2892133602 creator A5055412481 @default.
• W2892133602 creator A5073198015 @default.
• W2892133602 date "2018-09-21" @default.
• W2892133602 modified "2023-10-01" @default.
• W2892133602 title "Elevated circulating macrophage inhibitory cytokine 1 is a biological marker for the diagnosis and prognosis of osteosarcoma" @default.
• W2892133602 cites W1250740847 @default.
• W2892133602 cites W1782949453 @default.
• W2892133602 cites W1967768552 @default.
• W2892133602 cites W1985058596 @default.
• W2892133602 cites W1986662836 @default.
• W2892133602 cites W1989426535 @default.
• W2892133602 cites W2043994363 @default.
• W2892133602 cites W2068477388 @default.
• W2892133602 cites W2084154134 @default.
• W2892133602 cites W2093049275 @default.
• W2892133602 cites W2107277218 @default.
• W2892133602 cites W2110653270 @default.
• W2892133602 cites W2121921240 @default.
• W2892133602 cites W2139619092 @default.
• W2892133602 cites W2150960395 @default.
• W2892133602 cites W2151332282 @default.
• W2892133602 cites W2168601955 @default.
• W2892133602 cites W2177332611 @default.
• W2892133602 cites W2198846739 @default.
• W2892133602 cites W2226924068 @default.
• W2892133602 cites W2346520135 @default.
• W2892133602 cites W2409072188 @default.
• W2892133602 cites W2509833188 @default.
• W2892133602 cites W2518442327 @default.
• W2892133602 cites W2536236658 @default.
• W2892133602 cites W2602165580 @default.
• W2892133602 cites W2609395430 @default.
• W2892133602 cites W1964184380 @default.
• W2892133602 doi "https://doi.org/10.3892/etm.2018.6786" @default.
• W2892133602 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6257022" @default.
• W2892133602 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30546400" @default.
• W2892133602 hasPublicationYear "2018" @default.
• W2892133602 type Work @default.
• W2892133602 sameAs 2892133602 @default.
• W2892133602 citedByCount "0" @default.
• W2892133602 crossrefType "journal-article" @default.
• W2892133602 hasAuthorship W2892133602A5012611812 @default.
• W2892133602 hasAuthorship W2892133602A5033763955 @default.
• W2892133602 hasAuthorship W2892133602A5054310694 @default.
• W2892133602 hasAuthorship W2892133602A5055412481 @default.
• W2892133602 hasAuthorship W2892133602A5073198015 @default.
• W2892133602 hasBestOaLocation W28921336021 @default.
• W2892133602 hasConcept C104177226 @default.
• W2892133602 hasConcept C121608353 @default.
• W2892133602 hasConcept C126322002 @default.
• W2892133602 hasConcept C142724271 @default.
• W2892133602 hasConcept C143998085 @default.
• W2892133602 hasConcept C146357865 @default.
• W2892133602 hasConcept C151730666 @default.
• W2892133602 hasConcept C151956035 @default.
• W2892133602 hasConcept C203014093 @default.
• W2892133602 hasConcept C2777760704 @default.
• W2892133602 hasConcept C2778690821 @default.
• W2892133602 hasConcept C2781018059 @default.
• W2892133602 hasConcept C2781197716 @default.
• W2892133602 hasConcept C29537977 @default.
• W2892133602 hasConcept C38180746 @default.
• W2892133602 hasConcept C55493867 @default.
• W2892133602 hasConcept C67082663 @default.
• W2892133602 hasConcept C71924100 @default.
• W2892133602 hasConcept C86803240 @default.
• W2892133602 hasConceptScore W2892133602C104177226 @default.
• W2892133602 hasConceptScore W2892133602C121608353 @default.
• W2892133602 hasConceptScore W2892133602C126322002 @default.
• W2892133602 hasConceptScore W2892133602C142724271 @default.
• W2892133602 hasConceptScore W2892133602C143998085 @default.
• W2892133602 hasConceptScore W2892133602C146357865 @default.
• W2892133602 hasConceptScore W2892133602C151730666 @default.
• W2892133602 hasConceptScore W2892133602C151956035 @default.
• W2892133602 hasConceptScore W2892133602C203014093 @default.
• W2892133602 hasConceptScore W2892133602C2777760704 @default.
• W2892133602 hasConceptScore W2892133602C2778690821 @default.
• W2892133602 hasConceptScore W2892133602C2781018059 @default.
• W2892133602 hasConceptScore W2892133602C2781197716 @default.
• W2892133602 hasConceptScore W2892133602C29537977 @default.
• W2892133602 hasConceptScore W2892133602C38180746 @default.
• W2892133602 hasConceptScore W2892133602C55493867 @default.
• W2892133602 hasConceptScore W2892133602C67082663 @default.
• W2892133602 hasConceptScore W2892133602C71924100 @default.
• W2892133602 hasConceptScore W2892133602C86803240 @default.
• W2892133602 hasLocation W28921336021 @default.
• W2892133602 hasLocation W28921336022 @default.
• W2892133602 hasLocation W28921336023 @default.
• W2892133602 hasLocation W28921336024 @default.
• W2892133602 hasOpenAccess W2892133602 @default.
• W2892133602 hasPrimaryLocation W28921336021 @default.
• W2892133602 hasRelatedWork W1587725355 @default.
• W2892133602 hasRelatedWork W2089529379 @default.
• W2892133602 hasRelatedWork W2122953618 @default.
• W2892133602 hasRelatedWork W2156346117 @default.

• next