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- W2892168044 abstract "Dogs are unique because they are known to be the first species domesticated by humans, have the greatest morphological variation among terrestrial mammals, and exhibit unique bonds with humans. Yet, until very recently, the history of domestication and the associated consequences of this artificial selection have been a matter of speculation. Domesticated dogs are the ideal organism to study population genomics of domestication and the impact artificial selection has had on cognitive, social, behavioral, and disease traits. Because dogs have been associated with humans for tens of thousands of years, they are uniquely suited to investigate the genetic basis of selection for dietary adaptation during the agricultural revolution. Through a variety of large-scale genomics approaches, the history and consequences of dog domestication are no longer a matter of speculation. This chapter delves into the ancient origins of human-canine interactions and follows the domestication of wolves into dogs with a particular focus on (a) the selection of phenotypes underlying the strong bond between humans and their companion dogs, (b) the morphological variation underlying dog breeds, and (c) the genetic basis of canine diseases. The historical picture that is beginning to emerge provides a genomics framework for understanding why and how the dog became “our best friend.”" @default.
- W2892168044 created "2018-09-27" @default.
- W2892168044 creator A5006768938 @default.
- W2892168044 creator A5069826955 @default.
- W2892168044 date "2018-01-01" @default.
- W2892168044 modified "2023-09-27" @default.
- W2892168044 title "Population Genomics of Domestication and Breed Development in Canines in the Context of Cognitive, Social, Behavioral, and Disease Traits" @default.
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- W2892168044 doi "https://doi.org/10.1007/13836_2018_43" @default.
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