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• W2892202317 startingPage "172" @default.
• W2892202317 abstract "Extracellular matrix (ECM) materials have had remarkable success as scaffolds in tissue engineering (TE) and as therapies for tissue injury whereby the ECM microenvironment promotes constructive remodeling and tissue regeneration. ECM powder and solubilized derivatives thereof have novel applications in TE and RM afforded by the capacity of these constructs to be dynamically modulated. The powder form allows for effective incorporation and penetration of reagents; hence, ECM powder is an efficacious platform for 3D cell culture and vehicle for small molecule delivery. ECM powder offers minimally invasive therapy for tissue injury and successfully treatment for wounds refractory to first-line therapies. Comminution of ECM and fabrication of powder-derived constructs, however, may compromise the biological integrity of the ECM. The current lack of optimized fabrication protocols prevents a more extensive and effective clinical application of ECM powders. Further study on methods of ECM powder fabrication and modification is needed." @default.
• W2892202317 created "2018-09-27" @default.
• W2892202317 creator A5018638806 @default.
• W2892202317 creator A5019991245 @default.
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• W2892202317 creator A5066296164 @default.
• W2892202317 creator A5066466823 @default.
• W2892202317 creator A5090734452 @default.
• W2892202317 date "2018-09-05" @default.
• W2892202317 modified "2023-10-12" @default.
• W2892202317 title "Utility of extracellular matrix powders in tissue engineering" @default.
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