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- W2892215175 abstract "This study evaluated the effectiveness of formulary substitution from products or regimens containing name brand emtricitabine to alternative regimens containing generic lamivudine among virologically suppressed HIV-infected patients in a correctional managed health care system. Results of this retrospective cohort study showed that 94.9% of patients switched from emtricitabine to lamivudine (n = 447) and 93.0% of emtricitabine control patients (n = 449) had an undetectable viral load at last available test over a 2-year period. The two groups also showed similar values for CD4 counts, compliance, discontinuation, and M184V mutation; however, a slightly greater proportion of lamivudine patients experienced respiratory symptoms. Nonetheless, this study demonstrates that switching virologically suppressed HIV-infected patients from name brand emtricitabine-containing regimens to generic lamivudine-based regimens may reduce costs without compromising safety or effectiveness in correctional managed health care systems with directly observed therapy." @default.
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- W2892215175 date "2018-10-01" @default.
- W2892215175 modified "2023-10-14" @default.
- W2892215175 title "Substituting Generic Lamivudine for Emtricitabine in Virologically Suppressed HIV-Infected Patients" @default.
- W2892215175 doi "https://doi.org/10.1177/1078345818792843" @default.
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