Matches in SemOpenAlex for { <https://semopenalex.org/work/W2892220914> ?p ?o ?g. }
- W2892220914 endingPage "3171" @default.
- W2892220914 startingPage "3171" @default.
- W2892220914 abstract "Restricted feeding is well known to affect expression profiles of both clock and metabolic genes. However, it is unknown whether these changes in metabolic gene expression result from changes in the molecular clock or in feeding behavior. Here we eliminated the daily rhythm in feeding behavior by providing 6 meals evenly distributed over the light/dark-cycle. Animals on this 6-meals-a-day feeding schedule retained the normal day/night difference in physiological parameters including body temperature and locomotor activity. The daily rhythm in respiratory exchange ratio (RER), however, was significantly phase-shifted through increased utilization of carbohydrates during the light phase and increased lipid oxidation during the dark phase. This 6-meals-a-day feeding schedule did not have a major impact on the clock gene expression rhythms in the master clock, but did have mild effects on peripheral clocks. In contrast, genes involved in glucose and lipid metabolism showed differential expression. In conclusion, eliminating the daily rhythm in feeding behavior in rats does not affect the master clock and only mildly affects peripheral clocks, but disturbs metabolic rhythms in liver, skeletal muscle and brown adipose tissue in a tissue-dependent manner. Thereby, a clear daily rhythm in feeding behavior strongly regulates timing of peripheral metabolism, separately from circadian clocks." @default.
- W2892220914 created "2018-09-27" @default.
- W2892220914 creator A5015105013 @default.
- W2892220914 creator A5015927521 @default.
- W2892220914 creator A5017203989 @default.
- W2892220914 creator A5018565033 @default.
- W2892220914 creator A5024484224 @default.
- W2892220914 creator A5057118570 @default.
- W2892220914 creator A5079692848 @default.
- W2892220914 date "2018-10-15" @default.
- W2892220914 modified "2023-10-10" @default.
- W2892220914 title "An Ultradian Feeding Schedule in Rats Affects Metabolic Gene Expression in Liver, Brown Adipose Tissue and Skeletal Muscle with Only Mild Effects on Circadian Clocks" @default.
- W2892220914 cites W1746609183 @default.
- W2892220914 cites W1878804600 @default.
- W2892220914 cites W1894005404 @default.
- W2892220914 cites W1901438300 @default.
- W2892220914 cites W1965275927 @default.
- W2892220914 cites W1972334269 @default.
- W2892220914 cites W1973788573 @default.
- W2892220914 cites W1976905225 @default.
- W2892220914 cites W1988336402 @default.
- W2892220914 cites W1994973164 @default.
- W2892220914 cites W2003302378 @default.
- W2892220914 cites W2004333463 @default.
- W2892220914 cites W2006024610 @default.
- W2892220914 cites W2009132775 @default.
- W2892220914 cites W2016505696 @default.
- W2892220914 cites W2020343018 @default.
- W2892220914 cites W2021607553 @default.
- W2892220914 cites W2022558850 @default.
- W2892220914 cites W2023951795 @default.
- W2892220914 cites W2028832530 @default.
- W2892220914 cites W2043741320 @default.
- W2892220914 cites W2044961143 @default.
- W2892220914 cites W2064495012 @default.
- W2892220914 cites W2064693528 @default.
- W2892220914 cites W2066183013 @default.
- W2892220914 cites W2069163938 @default.
- W2892220914 cites W2071766083 @default.
- W2892220914 cites W2073462798 @default.
- W2892220914 cites W2073742199 @default.
- W2892220914 cites W2088348233 @default.
- W2892220914 cites W2089674063 @default.
- W2892220914 cites W2089817491 @default.
- W2892220914 cites W2091912666 @default.
- W2892220914 cites W2092503380 @default.
- W2892220914 cites W2093419981 @default.
- W2892220914 cites W2093505571 @default.
- W2892220914 cites W2102039847 @default.
- W2892220914 cites W2104290916 @default.
- W2892220914 cites W2104310168 @default.
- W2892220914 cites W2123319274 @default.
- W2892220914 cites W2133706171 @default.
- W2892220914 cites W2134377844 @default.
- W2892220914 cites W2137252071 @default.
- W2892220914 cites W2138503496 @default.
- W2892220914 cites W2142478420 @default.
- W2892220914 cites W2143210222 @default.
- W2892220914 cites W2147120373 @default.
- W2892220914 cites W2155305116 @default.
- W2892220914 cites W2157639171 @default.
- W2892220914 cites W2162291086 @default.
- W2892220914 cites W2164628441 @default.
- W2892220914 cites W2168271199 @default.
- W2892220914 cites W2170078281 @default.
- W2892220914 cites W2171703113 @default.
- W2892220914 cites W2175535734 @default.
- W2892220914 cites W2237552187 @default.
- W2892220914 cites W2264044325 @default.
- W2892220914 cites W2440558121 @default.
- W2892220914 cites W2507209340 @default.
- W2892220914 cites W2524239365 @default.
- W2892220914 cites W2527551486 @default.
- W2892220914 cites W2547816150 @default.
- W2892220914 cites W2562847852 @default.
- W2892220914 cites W2585404618 @default.
- W2892220914 cites W2592284210 @default.
- W2892220914 cites W2604705820 @default.
- W2892220914 cites W2612854134 @default.
- W2892220914 cites W2756001698 @default.
- W2892220914 cites W2765721539 @default.
- W2892220914 cites W2793948428 @default.
- W2892220914 cites W2800775048 @default.
- W2892220914 doi "https://doi.org/10.3390/ijms19103171" @default.
- W2892220914 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6214081" @default.
- W2892220914 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30326619" @default.
- W2892220914 hasPublicationYear "2018" @default.
- W2892220914 type Work @default.
- W2892220914 sameAs 2892220914 @default.
- W2892220914 citedByCount "13" @default.
- W2892220914 countsByYear W28922209142019 @default.
- W2892220914 countsByYear W28922209142020 @default.
- W2892220914 countsByYear W28922209142021 @default.
- W2892220914 countsByYear W28922209142022 @default.
- W2892220914 countsByYear W28922209142023 @default.
- W2892220914 crossrefType "journal-article" @default.
- W2892220914 hasAuthorship W2892220914A5015105013 @default.
- W2892220914 hasAuthorship W2892220914A5015927521 @default.