FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2892225144> ?p ?o ?g. }

• W2892225144 endingPage "3206.e4" @default.
• W2892225144 startingPage "3194" @default.
• W2892225144 abstract "A balanced diet of macronutrients is critical for animal health. A lack of specific elements can have profound effects on behavior, reproduction, and lifespan. Here, we used Drosophila to understand how the brain responds to carbohydrate deprivation. We found that serine protease homologs (SPHs) are enriched among genes that are transcriptionally regulated in flies deprived of carbohydrates. Stimulation of neurons expressing one of these SPHs, Scarface (Scaf), or overexpression of scaf positively regulates feeding on nutritious sugars, whereas inhibition of these neurons or knockdown of scaf reduces feeding. This modulation of food intake occurs only in sated flies while hunger-induced feeding is unaffected. Furthermore, scaf expression correlates with the presence of sugar in the food. As Scaf and Scaf neurons promote feeding independent of the hunger state, and the levels of scaf are positively regulated by the presence of sugar, we conclude that scaf mediates the hedonic control of feeding." @default.
• W2892225144 created "2018-09-27" @default.
• W2892225144 creator A5006207516 @default.
• W2892225144 creator A5088807975 @default.
• W2892225144 date "2018-09-01" @default.
• W2892225144 modified "2023-10-12" @default.
• W2892225144 title "Sugar Promotes Feeding in Flies via the Serine Protease Homolog scarface" @default.
• W2892225144 cites W1543226602 @default.
• W2892225144 cites W1561210734 @default.
• W2892225144 cites W1580426270 @default.
• W2892225144 cites W1689177678 @default.
• W2892225144 cites W1854999641 @default.
• W2892225144 cites W1863350518 @default.
• W2892225144 cites W1953569147 @default.
• W2892225144 cites W1968358311 @default.
• W2892225144 cites W1968659767 @default.
• W2892225144 cites W1969645371 @default.
• W2892225144 cites W1969837542 @default.
• W2892225144 cites W1978489579 @default.
• W2892225144 cites W1983727360 @default.
• W2892225144 cites W1995087873 @default.
• W2892225144 cites W1997522340 @default.
• W2892225144 cites W2004165690 @default.
• W2892225144 cites W2007027938 @default.
• W2892225144 cites W2009189044 @default.
• W2892225144 cites W2012195830 @default.
• W2892225144 cites W2016036283 @default.
• W2892225144 cites W2018080324 @default.
• W2892225144 cites W2022954501 @default.
• W2892225144 cites W2036056595 @default.
• W2892225144 cites W2037568077 @default.
• W2892225144 cites W2042438674 @default.
• W2892225144 cites W2045210487 @default.
• W2892225144 cites W2062222375 @default.
• W2892225144 cites W2062793520 @default.
• W2892225144 cites W2063854230 @default.
• W2892225144 cites W2070083683 @default.
• W2892225144 cites W2075668179 @default.
• W2892225144 cites W2079395662 @default.
• W2892225144 cites W2081092282 @default.
• W2892225144 cites W2084384443 @default.
• W2892225144 cites W2089049882 @default.
• W2892225144 cites W2092098765 @default.
• W2892225144 cites W2093534366 @default.
• W2892225144 cites W2100305481 @default.
• W2892225144 cites W2102658838 @default.
• W2892225144 cites W2105737177 @default.
• W2892225144 cites W2110120509 @default.
• W2892225144 cites W2125202857 @default.
• W2892225144 cites W2127051362 @default.
• W2892225144 cites W2131271579 @default.
• W2892225144 cites W2134976317 @default.
• W2892225144 cites W2135883403 @default.
• W2892225144 cites W2137555948 @default.
• W2892225144 cites W2140729960 @default.
• W2892225144 cites W2153068372 @default.
• W2892225144 cites W2154864066 @default.
• W2892225144 cites W2155001856 @default.
• W2892225144 cites W2156075933 @default.
• W2892225144 cites W2157765869 @default.
• W2892225144 cites W2158021738 @default.
• W2892225144 cites W2158370326 @default.
• W2892225144 cites W2162725445 @default.
• W2892225144 cites W2168132477 @default.
• W2892225144 cites W2216499887 @default.
• W2892225144 cites W2296826911 @default.
• W2892225144 cites W2413262053 @default.
• W2892225144 cites W2586494623 @default.
• W2892225144 cites W2587139956 @default.
• W2892225144 cites W4300926624 @default.
• W2892225144 doi "https://doi.org/10.1016/j.celrep.2018.08.059" @default.
• W2892225144 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6167639" @default.
• W2892225144 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30232002" @default.
• W2892225144 hasPublicationYear "2018" @default.
• W2892225144 type Work @default.
• W2892225144 sameAs 2892225144 @default.
• W2892225144 citedByCount "8" @default.
• W2892225144 countsByYear W28922251442019 @default.
• W2892225144 countsByYear W28922251442020 @default.
• W2892225144 countsByYear W28922251442021 @default.
• W2892225144 countsByYear W28922251442022 @default.
• W2892225144 countsByYear W28922251442023 @default.
• W2892225144 crossrefType "journal-article" @default.
• W2892225144 hasAuthorship W2892225144A5006207516 @default.
• W2892225144 hasAuthorship W2892225144A5088807975 @default.
• W2892225144 hasBestOaLocation W28922251441 @default.
• W2892225144 hasConcept C104317684 @default.
• W2892225144 hasConcept C173396325 @default.
• W2892225144 hasConcept C2777108408 @default.
• W2892225144 hasConcept C55493867 @default.
• W2892225144 hasConcept C86803240 @default.
• W2892225144 hasConcept C95444343 @default.
• W2892225144 hasConceptScore W2892225144C104317684 @default.
• W2892225144 hasConceptScore W2892225144C173396325 @default.
• W2892225144 hasConceptScore W2892225144C2777108408 @default.
• W2892225144 hasConceptScore W2892225144C55493867 @default.
• W2892225144 hasConceptScore W2892225144C86803240 @default.
• W2892225144 hasConceptScore W2892225144C95444343 @default.

• next