FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2892225533> ?p ?o ?g. }

• W2892225533 endingPage "4471" @default.
• W2892225533 startingPage "4460" @default.
• W2892225533 abstract "This study aimed to explore long noncoding RNAs (lncRNAs) implicated in dilated cardiomyopathy (DCM). Ten samples of failing hearts collected from the left ventricles of patients with DCM undergoing heart transplants, and ten control samples obtained from normal heart donors were included in this study. After sequencing, differentially expressed genes (DEGs) and lncRNAs between DCM and controls were screened, followed with functional enrichment analysis and weighted gene coexpression network analysis (WGCNA). Five key lncNRAs were validated through real-time polymerase chain reaction (PCR). Total 1,398 DEGs were identified, including 267 lncRNAs. WGCNA identified seven modules that were significantly correlated with DCM. The top 50 genes in the three modules (black, dark-green, and green–yellow) were significantly correlated with DCM disease state. Four core enrichment lncRNAs, such as AC061961.2, LING01-AS1, and RP11–557H15.4, in the green–yellow module were associated with neurotransmitter secretion. Five core enrichment lncRNAs, such as KB-1299A7.2 and RP11–13E1.5, in the black module were associated with the functions of blood circulation and heart contraction. AC061961.2, LING01-AS1, and RP11–13E1.5 were confirmed to be downregulated in DCM tissues by real-time PCR. The current study suggests that downregulation of AC061961.2, LING01-AS1, and RP11–13E1.5 may be associated with DCM progression, which may serve as key diagnostic biomarkers and therapeutic targets for DCM." @default.
• W2892225533 created "2018-09-27" @default.
• W2892225533 creator A5010320756 @default.
• W2892225533 creator A5012205818 @default.
• W2892225533 creator A5017489902 @default.
• W2892225533 creator A5029312878 @default.
• W2892225533 creator A5065285796 @default.
• W2892225533 creator A5083353087 @default.
• W2892225533 date "2018-09-10" @default.
• W2892225533 modified "2023-10-05" @default.
• W2892225533 title "Downregulation of AC061961.2, LING01‐AS1, and RP11–13E1.5 is associated with dilated cardiomyopathy progression" @default.
• W2892225533 cites W1966327575 @default.
• W2892225533 cites W1968953462 @default.
• W2892225533 cites W1976499891 @default.
• W2892225533 cites W2023952205 @default.
• W2892225533 cites W2035618305 @default.
• W2892225533 cites W2040411253 @default.
• W2892225533 cites W2043503153 @default.
• W2892225533 cites W2071942696 @default.
• W2892225533 cites W2072067798 @default.
• W2892225533 cites W2075447377 @default.
• W2892225533 cites W2086554842 @default.
• W2892225533 cites W2096173332 @default.
• W2892225533 cites W2096465161 @default.
• W2892225533 cites W2097065948 @default.
• W2892225533 cites W2104005232 @default.
• W2892225533 cites W2104052135 @default.
• W2892225533 cites W2109379548 @default.
• W2892225533 cites W2109874382 @default.
• W2892225533 cites W2111619469 @default.
• W2892225533 cites W2114104545 @default.
• W2892225533 cites W2121180999 @default.
• W2892225533 cites W2121604817 @default.
• W2892225533 cites W2127092408 @default.
• W2892225533 cites W2131274497 @default.
• W2892225533 cites W2135302420 @default.
• W2892225533 cites W2136294817 @default.
• W2892225533 cites W2136850043 @default.
• W2892225533 cites W2137854396 @default.
• W2892225533 cites W2159612327 @default.
• W2892225533 cites W2159675211 @default.
• W2892225533 cites W2159974171 @default.
• W2892225533 cites W2164608136 @default.
• W2892225533 cites W2320264340 @default.
• W2892225533 cites W2340288192 @default.
• W2892225533 cites W2435647547 @default.
• W2892225533 cites W2590601508 @default.
• W2892225533 cites W4211001885 @default.
• W2892225533 doi "https://doi.org/10.1002/jcp.27247" @default.
• W2892225533 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30203513" @default.
• W2892225533 hasPublicationYear "2018" @default.
• W2892225533 type Work @default.
• W2892225533 sameAs 2892225533 @default.
• W2892225533 citedByCount "20" @default.
• W2892225533 countsByYear W28922255332019 @default.
• W2892225533 countsByYear W28922255332020 @default.
• W2892225533 countsByYear W28922255332021 @default.
• W2892225533 countsByYear W28922255332022 @default.
• W2892225533 countsByYear W28922255332023 @default.
• W2892225533 crossrefType "journal-article" @default.
• W2892225533 hasAuthorship W2892225533A5010320756 @default.
• W2892225533 hasAuthorship W2892225533A5012205818 @default.
• W2892225533 hasAuthorship W2892225533A5017489902 @default.
• W2892225533 hasAuthorship W2892225533A5029312878 @default.
• W2892225533 hasAuthorship W2892225533A5065285796 @default.
• W2892225533 hasAuthorship W2892225533A5083353087 @default.
• W2892225533 hasConcept C104317684 @default.
• W2892225533 hasConcept C126322002 @default.
• W2892225533 hasConcept C127561419 @default.
• W2892225533 hasConcept C2776383484 @default.
• W2892225533 hasConcept C2778198053 @default.
• W2892225533 hasConcept C2778797674 @default.
• W2892225533 hasConcept C54355233 @default.
• W2892225533 hasConcept C71924100 @default.
• W2892225533 hasConcept C86803240 @default.
• W2892225533 hasConceptScore W2892225533C104317684 @default.
• W2892225533 hasConceptScore W2892225533C126322002 @default.
• W2892225533 hasConceptScore W2892225533C127561419 @default.
• W2892225533 hasConceptScore W2892225533C2776383484 @default.
• W2892225533 hasConceptScore W2892225533C2778198053 @default.
• W2892225533 hasConceptScore W2892225533C2778797674 @default.
• W2892225533 hasConceptScore W2892225533C54355233 @default.
• W2892225533 hasConceptScore W2892225533C71924100 @default.
• W2892225533 hasConceptScore W2892225533C86803240 @default.
• W2892225533 hasFunder F4320321001 @default.
• W2892225533 hasIssue "4" @default.
• W2892225533 hasLocation W28922255331 @default.
• W2892225533 hasLocation W28922255332 @default.
• W2892225533 hasOpenAccess W2892225533 @default.
• W2892225533 hasPrimaryLocation W28922255331 @default.
• W2892225533 hasRelatedWork W1567335236 @default.
• W2892225533 hasRelatedWork W175524388 @default.
• W2892225533 hasRelatedWork W2022117435 @default.
• W2892225533 hasRelatedWork W2053926010 @default.
• W2892225533 hasRelatedWork W2156053371 @default.
• W2892225533 hasRelatedWork W2163767443 @default.
• W2892225533 hasRelatedWork W2390570024 @default.
• W2892225533 hasRelatedWork W2976161251 @default.

• next