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- W2892232898 abstract "Wilson disease (WD) is a multisystem metabolic disorder affecting mainly, but not only, the liver and the central nervous system. It can present with a wide variety of symptoms including acute liver failure with or without encephalopathy, neurological symptoms, and psychiatric symptoms. The diverse nature of presentation means that there is no single symptom, sign, or test that is diagnostic. A timely diagnosis is of paramount importance, particularly in acute liver failure, so that appropriate treatment may be initiated. Patients presenting with classic Wilsonian liver failure require liver transplantation. WD patients presenting with less distinctive acute liver failure and encephalopathy are likely to require liver transplantation. When encephalopathy is not present with liver failure, it is important to be able to predict which patients would benefit from transplantation and which would improve with medical treatment. For these situations and others, diagnostic and prognostic scoring systems have been developed." @default.
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- W2892232898 date "2019-01-01" @default.
- W2892232898 modified "2023-10-14" @default.
- W2892232898 title "Role of Scoring Systems in Wilson Disease" @default.
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- W2892232898 doi "https://doi.org/10.1016/b978-0-12-810532-0.00025-2" @default.
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