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- W2892235703 abstract "Background: The radio-frequency catheter ablation (RFCA) therapy has 3 Achilles’ heels caused by the joule heat as an energy source. First, limited lesion depth due to heat transfer results in ineffectiveness for the treatment of ventricular arrhythmias of epicardial origin. Second, myoendocardial injury causes resultant thromboembolic complications. Third, post-procedural inflammation responses are sustained with subsequent early phase recurrences. In order to overcome these limitations of RFCA, we have been developing a shock wave catheter ablation (SWCA) system as a novel non-thermal therapy (Fig. A). We have previously demonstrated that we are able to create persistent AV block in pigs in vivo with a prototype catheter. In this study, we further examined the lesion effects of the SWCA. Methods and Results: We applied the newly-improved SWCA system to ventricular muscle of pigs in vivo. A total of 22 pigs were used for the following 3 protocols. (1) Epicardial approach: the lesion depth by the SW appli..." @default.
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- W2892235703 date "2016-11-11" @default.
- W2892235703 modified "2023-09-23" @default.
- W2892235703 title "Abstract 14126: Development of a Novel Shock Wave Catheter Ablation System -The Validation Study in Pigs in vivo" @default.
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