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- W2892256444 endingPage "2768" @default.
- W2892256444 startingPage "2768" @default.
- W2892256444 abstract "Gliomas are highly invasive brain tumors with short patient survival. One major pathogenic factor is aberrant tumor metabolism, which may be targeted with different specific and unspecific agents. Drug repurposing is of increasing interest in glioma research. Drugs interfering with the patient’s metabolism may also influence glioma metabolism. In this review, we outline definitions and methods for drug repurposing. Furthermore, we give insights into important candidates for a metabolic drug repurposing, namely metformin, statins, non-steroidal anti-inflammatory drugs, disulfiram and lonidamine. Advantages and pitfalls of drug repurposing will finally be discussed." @default.
- W2892256444 created "2018-09-27" @default.
- W2892256444 creator A5002677556 @default.
- W2892256444 creator A5039810007 @default.
- W2892256444 date "2018-09-14" @default.
- W2892256444 modified "2023-09-26" @default.
- W2892256444 title "Drug Repurposing of Metabolic Agents in Malignant Glioma" @default.
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