Matches in SemOpenAlex for { <https://semopenalex.org/work/W2892282934> ?p ?o ?g. }
- W2892282934 abstract "Abstract Specialized cells in the medial entorhinal cortex (mEC), such as speed cells, head direction (HD) cells, and grid cells, are thought to support spatial navigation. To determine whether these computations are dependent on local circuits, we record neuronal activity in mEC layers II and III and optogenetically perturb locally projecting layer II pyramidal cells. We find that sharply tuned HD cells are only weakly responsive while speed, broadly tuned HD cells, and grid cells show pronounced transient excitatory and inhibitory responses. During the brief period of feedback inhibition, there is a reduction in specifically grid accuracy, which is corrected as firing rates return to baseline. These results suggest that sharp HD cells are embedded in a separate mEC sub-network from broad HD cells, speed cells, and grid cells. Furthermore, grid tuning is not only dependent on local processing but also rapidly updated by HD, speed, or other afferent inputs to mEC." @default.
- W2892282934 created "2018-09-27" @default.
- W2892282934 creator A5006327764 @default.
- W2892282934 creator A5026860953 @default.
- W2892282934 creator A5057800679 @default.
- W2892282934 creator A5074928756 @default.
- W2892282934 creator A5078665068 @default.
- W2892282934 creator A5087186906 @default.
- W2892282934 date "2018-09-12" @default.
- W2892282934 modified "2023-10-14" @default.
- W2892282934 title "Recurrent circuits within medial entorhinal cortex superficial layers support grid cell firing" @default.
- W2892282934 cites W1512234833 @default.
- W2892282934 cites W1517826336 @default.
- W2892282934 cites W1725969320 @default.
- W2892282934 cites W1767661185 @default.
- W2892282934 cites W1970792572 @default.
- W2892282934 cites W1977366115 @default.
- W2892282934 cites W1981694662 @default.
- W2892282934 cites W1982195338 @default.
- W2892282934 cites W1986153736 @default.
- W2892282934 cites W1987775243 @default.
- W2892282934 cites W1997692559 @default.
- W2892282934 cites W1999856091 @default.
- W2892282934 cites W2001186755 @default.
- W2892282934 cites W2001515234 @default.
- W2892282934 cites W2006952639 @default.
- W2892282934 cites W2007814182 @default.
- W2892282934 cites W2008936540 @default.
- W2892282934 cites W2011081767 @default.
- W2892282934 cites W2013651116 @default.
- W2892282934 cites W2019035443 @default.
- W2892282934 cites W2019054821 @default.
- W2892282934 cites W2023161763 @default.
- W2892282934 cites W2034786388 @default.
- W2892282934 cites W2037343688 @default.
- W2892282934 cites W2046471865 @default.
- W2892282934 cites W2051916693 @default.
- W2892282934 cites W2061960110 @default.
- W2892282934 cites W2062205907 @default.
- W2892282934 cites W2063592395 @default.
- W2892282934 cites W2068578235 @default.
- W2892282934 cites W2070493436 @default.
- W2892282934 cites W2071627220 @default.
- W2892282934 cites W2072569914 @default.
- W2892282934 cites W2085256822 @default.
- W2892282934 cites W2085523626 @default.
- W2892282934 cites W2092048001 @default.
- W2892282934 cites W2092580449 @default.
- W2892282934 cites W2107852368 @default.
- W2892282934 cites W2114074055 @default.
- W2892282934 cites W2117443520 @default.
- W2892282934 cites W2131357693 @default.
- W2892282934 cites W2132238259 @default.
- W2892282934 cites W2132495470 @default.
- W2892282934 cites W2152829138 @default.
- W2892282934 cites W2162845416 @default.
- W2892282934 cites W2167279371 @default.
- W2892282934 cites W2167403166 @default.
- W2892282934 cites W2168156131 @default.
- W2892282934 cites W2200320834 @default.
- W2892282934 cites W2212004698 @default.
- W2892282934 cites W2318838494 @default.
- W2892282934 cites W2338208636 @default.
- W2892282934 cites W2416576494 @default.
- W2892282934 cites W2464751873 @default.
- W2892282934 cites W2482918638 @default.
- W2892282934 cites W2538414056 @default.
- W2892282934 cites W2564078948 @default.
- W2892282934 cites W2597771082 @default.
- W2892282934 cites W2601228807 @default.
- W2892282934 cites W2610604817 @default.
- W2892282934 cites W2759621709 @default.
- W2892282934 cites W4250313945 @default.
- W2892282934 doi "https://doi.org/10.1038/s41467-018-06104-5" @default.
- W2892282934 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6135799" @default.
- W2892282934 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30209250" @default.
- W2892282934 hasPublicationYear "2018" @default.
- W2892282934 type Work @default.
- W2892282934 sameAs 2892282934 @default.
- W2892282934 citedByCount "32" @default.
- W2892282934 countsByYear W28922829342018 @default.
- W2892282934 countsByYear W28922829342019 @default.
- W2892282934 countsByYear W28922829342020 @default.
- W2892282934 countsByYear W28922829342021 @default.
- W2892282934 countsByYear W28922829342022 @default.
- W2892282934 countsByYear W28922829342023 @default.
- W2892282934 crossrefType "journal-article" @default.
- W2892282934 hasAuthorship W2892282934A5006327764 @default.
- W2892282934 hasAuthorship W2892282934A5026860953 @default.
- W2892282934 hasAuthorship W2892282934A5057800679 @default.
- W2892282934 hasAuthorship W2892282934A5074928756 @default.
- W2892282934 hasAuthorship W2892282934A5078665068 @default.
- W2892282934 hasAuthorship W2892282934A5087186906 @default.
- W2892282934 hasBestOaLocation W28922829341 @default.
- W2892282934 hasConcept C102268210 @default.
- W2892282934 hasConcept C112592302 @default.
- W2892282934 hasConcept C11413529 @default.
- W2892282934 hasConcept C121332964 @default.
- W2892282934 hasConcept C1491633281 @default.
- W2892282934 hasConcept C169760540 @default.