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• W2892283965 abstract "Abstract Introduction BK polyomavirus ( BKP yV) continues to impact renal transplant recipients ( RTR ). The New England BK Consortium aims to jointly optimize screening and management of BKP yV. Methods Our first project was to survey centers’ BKP yV screening protocols and compare them to consensus guidelines. Results Thirteen of 15 centers (86.7%) returned the survey. Only two center reported using monitoring parameters that were in line with consensus guidelines for BKP yV screening, while the majority of centers reported less intensive methods and shorter duration. One center reported performing renal biopsies in all patients with plasma viral loads >10 000 copies/mL, while all other centers only perform for‐cause biopsies. For presumptive nephropathy, 11 centers recommend a biopsy for confirmation. For management of documented BKP yV‐associated nephropathy, 12 centers propose further immunosuppression reduction. Nine centers report CNI dose reduction as their primary treatment. More than half of centers surveyed reported use of leflunomide, cidofovir or intravenous immunoglobulin. Conclusions There was a large variance in BKP yV screening and management strategies among centers. Due to these results, all participating centers agreed to implement uniform screening and aim to optimize management protocols." @default.
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• W2892283965 date "2018-09-19" @default.
• W2892283965 modified "2023-10-17" @default.
• W2892283965 title "New England BK consortium: Regional survey of BK screening and management protocols in comparison to published consensus guidelines" @default.
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• W2892283965 doi "https://doi.org/10.1111/tid.12985" @default.
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