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• W2892288558 abstract "Introduction Endothelial progenitor cell (EPC) has shown in vitro and in vivo potential therapeutic angiogenesis, while there are still limitations related with improper vascular network. It is essential to optimize mature vessels. We hypothesized that EPC co-cultured with smooth muscle cell (SMC), a component of vascular pericyte, might induce robust and functional vessels, together with enhancing the angiogenic performance and preserving the endothelial-pericyte interaction. Methods and Results Primary EPC and SMC of male Wister rats were isolated and cultured. Expression of VEGF, HGF, TGFβ, and SDF1α in the culture supernatant in vitro was significantly greater in co-cultured EPC with SMC, compared to either EPC- or SMC-only, as assessed by ELISA. No significant difference was found in the concentrations of these cytokines between in the supernatant of “co-cultured” dish of both EPCs and SMCs plated together, and “separate-cultured” dish EPCs and SMCs plated onto the different layers using the trans-we..." @default.
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• W2892288558 date "2012-11-20" @default.
• W2892288558 modified "2023-09-28" @default.
• W2892288558 title "Abstract 11076: Tissue Engineered Complementary Endothelial Progenitor Cell Sheet to Reverse Adverse Ventricular Remodeling Following Ischemic Cardiomyopathy" @default.
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