FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2892306082> ?p ?o ?g. }

• W2892306082 endingPage "1570" @default.
• W2892306082 startingPage "1561" @default.
• W2892306082 abstract "BACKGROUND: Corneal blindness resulting from various medical conditions affects millions worldwide. The rapid developing tissue engineering field offers design of a scaffold with mechanical properties and transparency similar to that of the natural cornea.&#x0D; AIM: The present study aimed at to prepare and investigate the properties of PVA/chitosan blended scaffold by further cross-linking with 1-Ethyl-3-(3-dimethyl aminopropyl)-carbodiimide (EDC) and 2 N-Hydroxysuccinimide (NHS) as potential in vitro carrier for human limbal stem cells delivery.&#x0D; MATERIAL AND METHODS: Acetic acid dissolved chitosan was added to PVA solution, uniformly mixed with a homogenizer until the mixture was in a colloidal state, followed by H2SO4 and formaldehyde added and the sample was allowed to cool, subsequently it was poured into a tube and heated in an oven at 60°C for 50 minutes. Finally, samples were soaked in a cross-linking bath with EDC, NHS and NaOH in H2O/EtOH for 24 h consecutively stirred to cross-link the polymeric chains, reduce degradation. After soaking in the bath, the samples were carefully washed with 2% glycine aqueous solution several times to remove the remaining amount of cross-linkers, followed by washed with water to remove residual agents. Later the cross-linked scaffold subjected for various characterization and biological experiments.&#x0D; RESULTS: After viscosity measurement, the scaffold was observed by Fourier transform infrared (FT-IR). The water absorbency of PVA/Chitosan was increased 361% by swelling. Compression testing demonstrated that by increasing the amount of chitosan, the strength of the scaffold could be increased to 16×10−1 MPa. Our degradation results revealed by mass loss using equation shows that scaffold degraded gradually imply slow degradation. In vitro tests showed good cell proliferation and growth in the scaffold. Our assay results confirmed that the membrane could increase the cells adhesion and growth on the substrate.&#x0D; CONCLUSION: Hence, we strongly believe the use of this improved PVA/chitosan scaffold has potential to cut down the disadvantages of the human amniotic membrane (HAM) for corneal epithelium in ocular surface surgery and greater mechanical strength in future after successful experimentation with clinical trials." @default.
• W2892306082 created "2018-09-27" @default.
• W2892306082 creator A5010313637 @default.
• W2892306082 creator A5025801018 @default.
• W2892306082 date "2018-09-18" @default.
• W2892306082 modified "2023-09-26" @default.
• W2892306082 title "Evaluation of an Improved Chitosan Scaffold Cross-Linked With Polyvinyl Alcohol and Amine Coupling Through 1-Ethyl-3-(3-Dimethyl Aminopropyl)-Carbodiimide (EDC) and 2 N-Hydroxysuccinimide (NHS) for Corneal Applications" @default.
• W2892306082 cites W1487158340 @default.
• W2892306082 cites W1495550300 @default.
• W2892306082 cites W1497954906 @default.
• W2892306082 cites W186569128 @default.
• W2892306082 cites W1942187307 @default.
• W2892306082 cites W1968931227 @default.
• W2892306082 cites W1971491595 @default.
• W2892306082 cites W1975207418 @default.
• W2892306082 cites W1978862186 @default.
• W2892306082 cites W1986085958 @default.
• W2892306082 cites W1989307187 @default.
• W2892306082 cites W1992153927 @default.
• W2892306082 cites W1992495439 @default.
• W2892306082 cites W1993577427 @default.
• W2892306082 cites W2001903709 @default.
• W2892306082 cites W2003089235 @default.
• W2892306082 cites W2012473014 @default.
• W2892306082 cites W2021435146 @default.
• W2892306082 cites W2024286953 @default.
• W2892306082 cites W2032071390 @default.
• W2892306082 cites W2041558541 @default.
• W2892306082 cites W2042862773 @default.
• W2892306082 cites W2060181588 @default.
• W2892306082 cites W2060633086 @default.
• W2892306082 cites W2064720860 @default.
• W2892306082 cites W2064786704 @default.
• W2892306082 cites W2065386894 @default.
• W2892306082 cites W2067311110 @default.
• W2892306082 cites W2075722086 @default.
• W2892306082 cites W2076276686 @default.
• W2892306082 cites W2079123342 @default.
• W2892306082 cites W2082568449 @default.
• W2892306082 cites W2095725397 @default.
• W2892306082 cites W2096204864 @default.
• W2892306082 cites W2131647748 @default.
• W2892306082 cites W2132984034 @default.
• W2892306082 cites W2136287663 @default.
• W2892306082 cites W2148459495 @default.
• W2892306082 cites W2151261796 @default.
• W2892306082 cites W2160642072 @default.
• W2892306082 cites W2166369957 @default.
• W2892306082 cites W2166841658 @default.
• W2892306082 cites W2170226380 @default.
• W2892306082 cites W2293467158 @default.
• W2892306082 cites W2321623913 @default.
• W2892306082 cites W2496944137 @default.
• W2892306082 cites W2596045028 @default.
• W2892306082 cites W2606178280 @default.
• W2892306082 cites W2606384693 @default.
• W2892306082 cites W2740610303 @default.
• W2892306082 cites W2744601908 @default.
• W2892306082 cites W2762230717 @default.
• W2892306082 cites W2780387102 @default.
• W2892306082 cites W91877562 @default.
• W2892306082 doi "https://doi.org/10.3889/oamjms.2018.322" @default.
• W2892306082 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6182522" @default.
• W2892306082 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30337966" @default.
• W2892306082 hasPublicationYear "2018" @default.
• W2892306082 type Work @default.
• W2892306082 sameAs 2892306082 @default.
• W2892306082 citedByCount "12" @default.
• W2892306082 countsByYear W28923060822018 @default.
• W2892306082 countsByYear W28923060822019 @default.
• W2892306082 countsByYear W28923060822020 @default.
• W2892306082 countsByYear W28923060822021 @default.
• W2892306082 countsByYear W28923060822022 @default.
• W2892306082 countsByYear W28923060822023 @default.
• W2892306082 crossrefType "journal-article" @default.
• W2892306082 hasAuthorship W2892306082A5010313637 @default.
• W2892306082 hasAuthorship W2892306082A5025801018 @default.
• W2892306082 hasBestOaLocation W28923060821 @default.
• W2892306082 hasConcept C127413603 @default.
• W2892306082 hasConcept C136229726 @default.
• W2892306082 hasConcept C13965031 @default.
• W2892306082 hasConcept C159985019 @default.
• W2892306082 hasConcept C178790620 @default.
• W2892306082 hasConcept C184651966 @default.
• W2892306082 hasConcept C185592680 @default.
• W2892306082 hasConcept C188027245 @default.
• W2892306082 hasConcept C192562407 @default.
• W2892306082 hasConcept C2775997276 @default.
• W2892306082 hasConcept C2778551929 @default.
• W2892306082 hasConcept C2779732960 @default.
• W2892306082 hasConcept C42360764 @default.
• W2892306082 hasConcept C71924100 @default.
• W2892306082 hasConcept C89429830 @default.
• W2892306082 hasConceptScore W2892306082C127413603 @default.
• W2892306082 hasConceptScore W2892306082C136229726 @default.
• W2892306082 hasConceptScore W2892306082C13965031 @default.
• W2892306082 hasConceptScore W2892306082C159985019 @default.
• W2892306082 hasConceptScore W2892306082C178790620 @default.

• next