FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2892314338> ?p ?o ?g. }

• W2892314338 abstract "Context.— Human papillomavirus (HPV) DNA in situ hybridization (ISH) assay and p16 immunohistochemistry (IHC) are used to determine high-risk HPV status in formalin-fixed, paraffin-embedded (FFPE) tissues in oropharyngeal squamous cell carcinoma (SCC). Although high sensitivity and specificity for HPV can be obtained by combined p16 IHC and HPV DNA ISH, the occasional discrepancy between these assays has prompted evaluation of Cervista HPV assays in FFPE tissue from patients with oropharyngeal SCC. Objective.— To compare the efficacy of Cervista HPV 16/18 and Cervista HPV HR assay to that of HPV DNA ISH assay and p16 IHC in FFPE tissue in head and neck squamous cell carcinoma of oropharyngeal origin. Design.— Archived FFPE tissue from 84 patients with SCC of oropharyngeal origin and available HPV DNA ISH and p16 IHC test results were tested with the Cervista HPV 16/18 assay and further verified by polymerase chain reaction (PCR)–based HPV16/18 genotyping tests in cases with discrepancy. Results.— Of the 84 specimens, 75% (63 of 84) were positive and 16% (13 of 84) had discrepant or equivocal findings by p16 IHC and HPV DNA ISH testing. Use of Cervista HPV assays, either to clarify discrepant/equivocal findings or as confirmation after initial p16 IHC/HPV DNA ISH tests, identified 81% (68 of 84) of HPV-positive cases without equivocal HPV results. Five of 13 cases with discrepancy or equivocal HPV DNA ISH results tested positive for HPV16 or HPV18 by Cervista HPV 16/18 assay, which was further confirmed by PCR-based HPV 16/18 genotyping. Conclusions.— The Cervista HPV assays are a reasonable alternative to HPV DNA ISH in determining HPV status in FFPE tissue specimens from patients with oropharyngeal SCC." @default.
• W2892314338 created "2018-09-27" @default.
• W2892314338 creator A5023372230 @default.
• W2892314338 creator A5045409917 @default.
• W2892314338 creator A5049403047 @default.
• W2892314338 creator A5055890072 @default.
• W2892314338 creator A5062385539 @default.
• W2892314338 creator A5069538294 @default.
• W2892314338 creator A5070156025 @default.
• W2892314338 creator A5073315000 @default.
• W2892314338 creator A5088293773 @default.
• W2892314338 date "2018-09-17" @default.
• W2892314338 modified "2023-09-24" @default.
• W2892314338 title "Incorporation of Cervista Human Papillomavirus 16/18 Assay Into Algorithms for Classifying Human Papillomavirus Status in Formalin-Fixed, Paraffin-Embedded Head and Neck Squamous Carcinoma Specimens" @default.
• W2892314338 cites W1482866244 @default.
• W2892314338 cites W1968108709 @default.
• W2892314338 cites W1983019576 @default.
• W2892314338 cites W1996456132 @default.
• W2892314338 cites W2025021599 @default.
• W2892314338 cites W2031123636 @default.
• W2892314338 cites W2033316661 @default.
• W2892314338 cites W2033544246 @default.
• W2892314338 cites W2060763328 @default.
• W2892314338 cites W2082894170 @default.
• W2892314338 cites W2085283758 @default.
• W2892314338 cites W2095689320 @default.
• W2892314338 cites W2110664940 @default.
• W2892314338 cites W2118999598 @default.
• W2892314338 cites W2132239791 @default.
• W2892314338 cites W2135527553 @default.
• W2892314338 cites W2143680521 @default.
• W2892314338 cites W2144589156 @default.
• W2892314338 cites W2149166037 @default.
• W2892314338 cites W2159339937 @default.
• W2892314338 cites W2167138865 @default.
• W2892314338 cites W2169631870 @default.
• W2892314338 cites W2170178908 @default.
• W2892314338 cites W2318564463 @default.
• W2892314338 cites W2320299038 @default.
• W2892314338 cites W2335162820 @default.
• W2892314338 cites W2342113665 @default.
• W2892314338 cites W2560036924 @default.
• W2892314338 cites W2593249930 @default.
• W2892314338 cites W2184638675 @default.
• W2892314338 doi "https://doi.org/10.5858/arpa.2017-0469-oa" @default.
• W2892314338 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30221979" @default.
• W2892314338 hasPublicationYear "2018" @default.
• W2892314338 type Work @default.
• W2892314338 sameAs 2892314338 @default.
• W2892314338 citedByCount "0" @default.
• W2892314338 crossrefType "journal-article" @default.
• W2892314338 hasAuthorship W2892314338A5023372230 @default.
• W2892314338 hasAuthorship W2892314338A5045409917 @default.
• W2892314338 hasAuthorship W2892314338A5049403047 @default.
• W2892314338 hasAuthorship W2892314338A5055890072 @default.
• W2892314338 hasAuthorship W2892314338A5062385539 @default.
• W2892314338 hasAuthorship W2892314338A5069538294 @default.
• W2892314338 hasAuthorship W2892314338A5070156025 @default.
• W2892314338 hasAuthorship W2892314338A5073315000 @default.
• W2892314338 hasAuthorship W2892314338A5088293773 @default.
• W2892314338 hasBestOaLocation W28923143381 @default.
• W2892314338 hasConcept C104317684 @default.
• W2892314338 hasConcept C121608353 @default.
• W2892314338 hasConcept C126322002 @default.
• W2892314338 hasConcept C135763542 @default.
• W2892314338 hasConcept C142724271 @default.
• W2892314338 hasConcept C150194340 @default.
• W2892314338 hasConcept C204232928 @default.
• W2892314338 hasConcept C2776530083 @default.
• W2892314338 hasConcept C2776833033 @default.
• W2892314338 hasConcept C2994532551 @default.
• W2892314338 hasConcept C31467283 @default.
• W2892314338 hasConcept C49105822 @default.
• W2892314338 hasConcept C55493867 @default.
• W2892314338 hasConcept C71924100 @default.
• W2892314338 hasConcept C81439078 @default.
• W2892314338 hasConcept C86803240 @default.
• W2892314338 hasConceptScore W2892314338C104317684 @default.
• W2892314338 hasConceptScore W2892314338C121608353 @default.
• W2892314338 hasConceptScore W2892314338C126322002 @default.
• W2892314338 hasConceptScore W2892314338C135763542 @default.
• W2892314338 hasConceptScore W2892314338C142724271 @default.
• W2892314338 hasConceptScore W2892314338C150194340 @default.
• W2892314338 hasConceptScore W2892314338C204232928 @default.
• W2892314338 hasConceptScore W2892314338C2776530083 @default.
• W2892314338 hasConceptScore W2892314338C2776833033 @default.
• W2892314338 hasConceptScore W2892314338C2994532551 @default.
• W2892314338 hasConceptScore W2892314338C31467283 @default.
• W2892314338 hasConceptScore W2892314338C49105822 @default.
• W2892314338 hasConceptScore W2892314338C55493867 @default.
• W2892314338 hasConceptScore W2892314338C71924100 @default.
• W2892314338 hasConceptScore W2892314338C81439078 @default.
• W2892314338 hasConceptScore W2892314338C86803240 @default.
• W2892314338 hasLocation W28923143381 @default.
• W2892314338 hasLocation W28923143382 @default.
• W2892314338 hasOpenAccess W2892314338 @default.
• W2892314338 hasPrimaryLocation W28923143381 @default.
• W2892314338 hasRelatedWork W1999108147 @default.
• W2892314338 hasRelatedWork W2040358045 @default.
• W2892314338 hasRelatedWork W2054521663 @default.

• next