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- W2892337114 endingPage "330" @default.
- W2892337114 startingPage "309" @default.
- W2892337114 abstract "2017 marks the 60th anniversary of Krebs’ seminal paper on the glyoxylate shunt (and coincidentally, also the 80th anniversary of his discovery of the citric acid cycle). Sixty years on, we have witnessed substantial developments in our understanding of how flux is partitioned between the glyoxylate shunt and the oxidative decarboxylation steps of the citric acid cycle. The last decade has shown us that the beautifully elegant textbook mechanism that regulates carbon flux through the shunt in E. coli is an oversimplification of the situation in many other bacteria. The aim of this review is to assess how this new knowledge is impacting our understanding of flux control at the TCA cycle/glyoxylate shunt branch point in a wider range of genera, and to summarize recent findings implicating a role for the glyoxylate shunt in cellular functions other than metabolism." @default.
- W2892337114 created "2018-09-27" @default.
- W2892337114 creator A5025361332 @default.
- W2892337114 creator A5057438504 @default.
- W2892337114 date "2018-09-08" @default.
- W2892337114 modified "2023-10-16" @default.
- W2892337114 title "The Glyoxylate Shunt, 60 Years On" @default.
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- W2892337114 doi "https://doi.org/10.1146/annurev-micro-090817-062257" @default.
- W2892337114 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30200852" @default.
- W2892337114 hasPublicationYear "2018" @default.
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