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- W2892340344 endingPage "2281" @default.
- W2892340344 startingPage "2273" @default.
- W2892340344 abstract "Hematopoietic stem cells differentiate into all types of blood cells, including peripheral tissue-resident mast cells. The early mast cell differentiation takes place in the bone marrow, after which the progenitor cells enter the circulation and mature once reaching their target organ. Early results from single-cell culture experiments and colony-forming assays have produced the classic hierarchical tree model of hematopoiesis. The introduction of high-throughput, single-cell RNA sequencing is now revolutionizing our understanding of the differentiation process, questioning the classic tree-based models. By integrating the results from early cell culture experiments with single-cell transcriptomics, we present a differentiation landscape model of hematopoiesis and discuss it with focus on mast cells. The review also describes how the hematologic neoplasm systemic mastocytosis can be used to model human hematopoiesis using naturally occurring cell barcoding by means of the common KIT D816V mutation." @default.
- W2892340344 created "2018-09-27" @default.
- W2892340344 creator A5003150190 @default.
- W2892340344 creator A5016859188 @default.
- W2892340344 creator A5052904126 @default.
- W2892340344 creator A5085510498 @default.
- W2892340344 date "2018-09-11" @default.
- W2892340344 modified "2023-10-14" @default.
- W2892340344 title "Deciphering the differentiation trajectory from hematopoietic stem cells to mast cells" @default.
- W2892340344 cites W146067998 @default.
- W2892340344 cites W1511722376 @default.
- W2892340344 cites W1559935336 @default.
- W2892340344 cites W1584938444 @default.
- W2892340344 cites W1586878534 @default.
- W2892340344 cites W1631782483 @default.
- W2892340344 cites W171982086 @default.
- W2892340344 cites W1783032344 @default.
- W2892340344 cites W1806230168 @default.
- W2892340344 cites W1839825739 @default.
- W2892340344 cites W1915358631 @default.
- W2892340344 cites W1959193977 @default.
- W2892340344 cites W1967385939 @default.
- W2892340344 cites W1972144397 @default.
- W2892340344 cites W1981890042 @default.
- W2892340344 cites W1981910171 @default.
- W2892340344 cites W1982256713 @default.
- W2892340344 cites W1987628847 @default.
- W2892340344 cites W1988479465 @default.
- W2892340344 cites W1992904489 @default.
- W2892340344 cites W1994199588 @default.
- W2892340344 cites W2004561916 @default.
- W2892340344 cites W2006905792 @default.
- W2892340344 cites W2010221405 @default.
- W2892340344 cites W2013848096 @default.
- W2892340344 cites W2018111982 @default.
- W2892340344 cites W2019100913 @default.
- W2892340344 cites W2021557819 @default.
- W2892340344 cites W2021564657 @default.
- W2892340344 cites W2028379873 @default.
- W2892340344 cites W2028988446 @default.
- W2892340344 cites W2029995552 @default.
- W2892340344 cites W2034207263 @default.
- W2892340344 cites W2035632882 @default.
- W2892340344 cites W2040179104 @default.
- W2892340344 cites W2043387647 @default.
- W2892340344 cites W2052337657 @default.
- W2892340344 cites W2054846695 @default.
- W2892340344 cites W2057090515 @default.
- W2892340344 cites W2058511974 @default.
- W2892340344 cites W2062818637 @default.
- W2892340344 cites W2064582651 @default.
- W2892340344 cites W2067688555 @default.
- W2892340344 cites W2070125949 @default.
- W2892340344 cites W2085825003 @default.
- W2892340344 cites W2090205957 @default.
- W2892340344 cites W2090786449 @default.
- W2892340344 cites W2100961977 @default.
- W2892340344 cites W2102421434 @default.
- W2892340344 cites W2109331088 @default.
- W2892340344 cites W2115823813 @default.
- W2892340344 cites W2127559729 @default.
- W2892340344 cites W2139053623 @default.
- W2892340344 cites W2141580515 @default.
- W2892340344 cites W2151022082 @default.
- W2892340344 cites W2156976032 @default.
- W2892340344 cites W2161676168 @default.
- W2892340344 cites W2170248440 @default.
- W2892340344 cites W2177432730 @default.
- W2892340344 cites W2293196298 @default.
- W2892340344 cites W2295606103 @default.
- W2892340344 cites W2296776321 @default.
- W2892340344 cites W2325223081 @default.
- W2892340344 cites W2336303117 @default.
- W2892340344 cites W2339720644 @default.
- W2892340344 cites W2342825119 @default.
- W2892340344 cites W2347163170 @default.
- W2892340344 cites W2416463307 @default.
- W2892340344 cites W2417506156 @default.
- W2892340344 cites W2465917013 @default.
- W2892340344 cites W24802265 @default.
- W2892340344 cites W2515907404 @default.
- W2892340344 cites W2565342730 @default.
- W2892340344 cites W2598139181 @default.
- W2892340344 cites W2602848567 @default.
- W2892340344 cites W2743027761 @default.
- W2892340344 cites W2766383394 @default.
- W2892340344 cites W2784100784 @default.
- W2892340344 cites W2788263670 @default.
- W2892340344 cites W2790847351 @default.
- W2892340344 cites W2794765397 @default.
- W2892340344 cites W2807207064 @default.
- W2892340344 cites W35004115 @default.
- W2892340344 cites W4237115562 @default.
- W2892340344 cites W4245821924 @default.
- W2892340344 cites W4253107274 @default.
- W2892340344 cites W4313335099 @default.
- W2892340344 cites W65045043 @default.
- W2892340344 cites W79365468 @default.