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• W2892345853 abstract "Abstract The widespread use and progress in modern imaging modalities have led to an increase in the incidental finding of asymptomatic benign hepatic lesions, including cystic and solid tumors. In contrast to most cystic lesions, the latter group is composed of tumors that often harbor true neoplastic characteristics. The most frequent benign solid lesions are hemangioma and focal nodular hyperplasia, which only rarely require treatment or long-term follow-up. Less frequent lesions include hepatocellular adenoma and angiomyolipoma, which carry a higher risk for complications, such as bleeding or malignant transformation, and therefore are more likely to necessitate surgical intervention. To account for these marked differences in biology and clinical characteristics between the different tumor types and ensure an accurate diagnosis, as well as an appropriate management of the patients, it is crucial to have a thorough understanding of clinical, biologic, radiologic, and pathologic characteristics of each liver lesion. Indeed, refinements in magnetic resonance imaging and contrast-enhanced ultrasonography and computed tomography allow an accurate diagnosis based only on imaging in a majority of cases and have thus strongly reduced the need for percutaneous biopsy or surgical resection for final diagnosis. After the diagnosis has been established, the vast majority of benign hepatic neoplasms do not require surgical resection. However, indications for surgery include diagnostic uncertainty after an extensive diagnostic work-up, symptomatic patients, lesions with a mass effect on gastrointestinal organs or the biliary tree and tumors that have a potential for complications, as well as malignant transformation. In this chapter, we will cover solid benign hepatic lesions in adults and describe the etiology, clinical presentation, diagnostic work-up, and treatment strategy for each tumor type." @default.
• W2892345853 created "2018-09-27" @default.
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• W2892345853 date "2019-01-01" @default.
• W2892345853 modified "2023-10-17" @default.
• W2892345853 title "Benign Hepatic Neoplasms" @default.
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• W2892345853 doi "https://doi.org/10.1016/b978-0-323-40232-3.00131-x" @default.
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