FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2892347345> ?p ?o ?g. }

• W2892347345 abstract "Abstract Immunoglobulin G (IgG) N - glycosylation is crucial for its effector functions. It is a complex trait, and large sample sets are needed to discover multiple genetic factors that underlie it. While in humans such high-throughput studies of IgG N-glycans became usual, only one has been carried out in mice. Here we describe and validate a method for the relative quantification of IgG Fc-linked N - glycans in a subclass-specific manner using nano-reverse phase liquid chromatography coupled with mass-spectrometry (nanoRP-LC-MS) applied to murine IgG. High-throughput data processing is ensured by the LaCyTools software. We have shown that IgG isolation procedure is the main source of technical variation in the current protocol. The major glycoforms were quantified reliably with coefficients of variation below 6% for all the analytes with relative abundances above 5%. We have applied our method to a sample set of 3 inbred strains: BALB/c, C57BL/6 and C3H and observed differences in subclass-specific and strain - specific N - glycosylation of IgG, suggesting a significant genetic component in the regulation of Fc-linked IgG N - glycosylation." @default.
• W2892347345 created "2018-09-27" @default.
• W2892347345 creator A5003751922 @default.
• W2892347345 creator A5005667553 @default.
• W2892347345 creator A5011326045 @default.
• W2892347345 creator A5030718200 @default.
• W2892347345 creator A5033784017 @default.
• W2892347345 creator A5038051461 @default.
• W2892347345 creator A5052845799 @default.
• W2892347345 creator A5068397052 @default.
• W2892347345 creator A5079892476 @default.
• W2892347345 creator A5081866196 @default.
• W2892347345 creator A5088377589 @default.
• W2892347345 date "2018-09-12" @default.
• W2892347345 modified "2023-10-12" @default.
• W2892347345 title "MIgGGly (mouse IgG glycosylation analysis) - a high-throughput method for studying Fc-linked IgG N-glycosylation in mice with nanoUPLC-ESI-MS" @default.
• W2892347345 cites W1495576644 @default.
• W2892347345 cites W1603974154 @default.
• W2892347345 cites W1634312914 @default.
• W2892347345 cites W1771609665 @default.
• W2892347345 cites W1815989564 @default.
• W2892347345 cites W1955979675 @default.
• W2892347345 cites W1958142025 @default.
• W2892347345 cites W1964180982 @default.
• W2892347345 cites W1969824500 @default.
• W2892347345 cites W1969977433 @default.
• W2892347345 cites W1992886596 @default.
• W2892347345 cites W1993591613 @default.
• W2892347345 cites W2007527241 @default.
• W2892347345 cites W2011537324 @default.
• W2892347345 cites W2016008184 @default.
• W2892347345 cites W2017065556 @default.
• W2892347345 cites W2029522688 @default.
• W2892347345 cites W2030202214 @default.
• W2892347345 cites W2036736853 @default.
• W2892347345 cites W2037007095 @default.
• W2892347345 cites W2037117519 @default.
• W2892347345 cites W2039351002 @default.
• W2892347345 cites W2057745345 @default.
• W2892347345 cites W2061641422 @default.
• W2892347345 cites W2067367025 @default.
• W2892347345 cites W2073514249 @default.
• W2892347345 cites W2074910307 @default.
• W2892347345 cites W2075473217 @default.
• W2892347345 cites W2083205212 @default.
• W2892347345 cites W2084058293 @default.
• W2892347345 cites W2092329879 @default.
• W2892347345 cites W2101939433 @default.
• W2892347345 cites W2109963121 @default.
• W2892347345 cites W2110990893 @default.
• W2892347345 cites W2111016103 @default.
• W2892347345 cites W2124764330 @default.
• W2892347345 cites W2131524456 @default.
• W2892347345 cites W2136722035 @default.
• W2892347345 cites W2140723605 @default.
• W2892347345 cites W2148830338 @default.
• W2892347345 cites W2154100133 @default.
• W2892347345 cites W2154841949 @default.
• W2892347345 cites W2161771297 @default.
• W2892347345 cites W2169656611 @default.
• W2892347345 cites W2172466148 @default.
• W2892347345 cites W2337018559 @default.
• W2892347345 cites W2337334490 @default.
• W2892347345 cites W2405819699 @default.
• W2892347345 cites W2428554179 @default.
• W2892347345 cites W2442134451 @default.
• W2892347345 cites W2515423876 @default.
• W2892347345 cites W2517729572 @default.
• W2892347345 cites W2519861672 @default.
• W2892347345 cites W2561217603 @default.
• W2892347345 cites W2596270747 @default.
• W2892347345 cites W2616844168 @default.
• W2892347345 cites W2617185274 @default.
• W2892347345 cites W2622369154 @default.
• W2892347345 cites W2738701928 @default.
• W2892347345 cites W2743062554 @default.
• W2892347345 cites W2762529457 @default.
• W2892347345 cites W2797563486 @default.
• W2892347345 cites W2799991032 @default.
• W2892347345 doi "https://doi.org/10.1038/s41598-018-31844-1" @default.
• W2892347345 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6135756" @default.
• W2892347345 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30209257" @default.
• W2892347345 hasPublicationYear "2018" @default.
• W2892347345 type Work @default.
• W2892347345 sameAs 2892347345 @default.
• W2892347345 citedByCount "17" @default.
• W2892347345 countsByYear W28923473452020 @default.
• W2892347345 countsByYear W28923473452021 @default.
• W2892347345 countsByYear W28923473452022 @default.
• W2892347345 countsByYear W28923473452023 @default.
• W2892347345 crossrefType "journal-article" @default.
• W2892347345 hasAuthorship W2892347345A5003751922 @default.
• W2892347345 hasAuthorship W2892347345A5005667553 @default.
• W2892347345 hasAuthorship W2892347345A5011326045 @default.
• W2892347345 hasAuthorship W2892347345A5030718200 @default.
• W2892347345 hasAuthorship W2892347345A5033784017 @default.
• W2892347345 hasAuthorship W2892347345A5038051461 @default.
• W2892347345 hasAuthorship W2892347345A5052845799 @default.
• W2892347345 hasAuthorship W2892347345A5068397052 @default.
• W2892347345 hasAuthorship W2892347345A5079892476 @default.

• next