FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2892360355> ?p ?o ?g. }

• W2892360355 abstract "Endogenous β-endorphin is delivered exclusively from the pituitary gland in various stressful conditions and plays an essential role in the nervous system. Recently, a few studies demonstrated peripheral endogenous opioid secretion from immune cells at inflammatory sites. Here, we investigated the expression of β-endorphin, the most powerful endogenous opioid peptide, in peripheral tissues in response to systemic administration of lipopolysaccharide in mice.Male C57BL/6N mice received intravenously administered lipopolysaccharide to induce an endotoxic shock-like condition. mRNA for proopiomelanocortin, a precursor of β-endorphin, was quantified in peripheral blood cells, liver and spleen. β-endorphin peptide was measured in the liver and spleen.Expression of proopiomelanocortin mRNA was detected in peripheral tissues after systemic administration of lipopolysaccharide. Lipopolysaccharide also induced β-endorphin expression in the liver and spleen.Expression of proopiomelanocortin mRNA and β-endorphin was detected in peripheral tissues after systemic administration of lipopolysaccharide. These results provide new evidence that peripheral endogenous opioids can be produced not only as a result of local inflammation but also by severe systemic stress such as endotoxic shock. Further study is required to clarify the role of peripheral β-endorphin during endotoxic shock." @default.
• W2892360355 created "2018-09-27" @default.
• W2892360355 creator A5006257540 @default.
• W2892360355 creator A5019279939 @default.
• W2892360355 creator A5068749796 @default.
• W2892360355 creator A5070183376 @default.
• W2892360355 date "2019-04-01" @default.
• W2892360355 modified "2023-09-24" @default.
• W2892360355 title "Expression of β-endorphin in peripheral tissues after systemic administration of lipopolysaccharide as a model of endotoxic shock in mice" @default.
• W2892360355 cites W1931401743 @default.
• W2892360355 cites W1963627122 @default.
• W2892360355 cites W1968490986 @default.
• W2892360355 cites W1972286336 @default.
• W2892360355 cites W1975569088 @default.
• W2892360355 cites W2012162544 @default.
• W2892360355 cites W2018553528 @default.
• W2892360355 cites W2036407725 @default.
• W2892360355 cites W2041935994 @default.
• W2892360355 cites W2047770015 @default.
• W2892360355 cites W2053732295 @default.
• W2892360355 cites W2054705103 @default.
• W2892360355 cites W2059730682 @default.
• W2892360355 cites W2060928705 @default.
• W2892360355 cites W2065776525 @default.
• W2892360355 cites W2076635491 @default.
• W2892360355 cites W2078177376 @default.
• W2892360355 cites W2088734080 @default.
• W2892360355 cites W2090452425 @default.
• W2892360355 cites W2102412754 @default.
• W2892360355 cites W2113535256 @default.
• W2892360355 cites W2114382165 @default.
• W2892360355 cites W2118602509 @default.
• W2892360355 cites W2130135920 @default.
• W2892360355 cites W2192643413 @default.
• W2892360355 cites W2550507245 @default.
• W2892360355 cites W2784412824 @default.
• W2892360355 doi "https://doi.org/10.1016/j.ando.2018.06.001" @default.
• W2892360355 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30243475" @default.
• W2892360355 hasPublicationYear "2019" @default.
• W2892360355 type Work @default.
• W2892360355 sameAs 2892360355 @default.
• W2892360355 citedByCount "5" @default.
• W2892360355 countsByYear W28923603552019 @default.
• W2892360355 countsByYear W28923603552020 @default.
• W2892360355 crossrefType "journal-article" @default.
• W2892360355 hasAuthorship W2892360355A5006257540 @default.
• W2892360355 hasAuthorship W2892360355A5019279939 @default.
• W2892360355 hasAuthorship W2892360355A5068749796 @default.
• W2892360355 hasAuthorship W2892360355A5070183376 @default.
• W2892360355 hasConcept C126322002 @default.
• W2892360355 hasConcept C134018914 @default.
• W2892360355 hasConcept C150903083 @default.
• W2892360355 hasConcept C16613235 @default.
• W2892360355 hasConcept C170493617 @default.
• W2892360355 hasConcept C203014093 @default.
• W2892360355 hasConcept C207001950 @default.
• W2892360355 hasConcept C25938499 @default.
• W2892360355 hasConcept C2776914184 @default.
• W2892360355 hasConcept C2777003273 @default.
• W2892360355 hasConcept C2778754761 @default.
• W2892360355 hasConcept C2780931953 @default.
• W2892360355 hasConcept C2781063702 @default.
• W2892360355 hasConcept C2781309135 @default.
• W2892360355 hasConcept C3017995582 @default.
• W2892360355 hasConcept C46762472 @default.
• W2892360355 hasConcept C71924100 @default.
• W2892360355 hasConcept C86803240 @default.
• W2892360355 hasConcept C88016717 @default.
• W2892360355 hasConcept C8891405 @default.
• W2892360355 hasConceptScore W2892360355C126322002 @default.
• W2892360355 hasConceptScore W2892360355C134018914 @default.
• W2892360355 hasConceptScore W2892360355C150903083 @default.
• W2892360355 hasConceptScore W2892360355C16613235 @default.
• W2892360355 hasConceptScore W2892360355C170493617 @default.
• W2892360355 hasConceptScore W2892360355C203014093 @default.
• W2892360355 hasConceptScore W2892360355C207001950 @default.
• W2892360355 hasConceptScore W2892360355C25938499 @default.
• W2892360355 hasConceptScore W2892360355C2776914184 @default.
• W2892360355 hasConceptScore W2892360355C2777003273 @default.
• W2892360355 hasConceptScore W2892360355C2778754761 @default.
• W2892360355 hasConceptScore W2892360355C2780931953 @default.
• W2892360355 hasConceptScore W2892360355C2781063702 @default.
• W2892360355 hasConceptScore W2892360355C2781309135 @default.
• W2892360355 hasConceptScore W2892360355C3017995582 @default.
• W2892360355 hasConceptScore W2892360355C46762472 @default.
• W2892360355 hasConceptScore W2892360355C71924100 @default.
• W2892360355 hasConceptScore W2892360355C86803240 @default.
• W2892360355 hasConceptScore W2892360355C88016717 @default.
• W2892360355 hasConceptScore W2892360355C8891405 @default.
• W2892360355 hasLocation W28923603551 @default.
• W2892360355 hasLocation W28923603552 @default.
• W2892360355 hasOpenAccess W2892360355 @default.
• W2892360355 hasPrimaryLocation W28923603551 @default.
• W2892360355 hasRelatedWork W1966943429 @default.
• W2892360355 hasRelatedWork W1983913647 @default.
• W2892360355 hasRelatedWork W1988120818 @default.
• W2892360355 hasRelatedWork W1993159694 @default.
• W2892360355 hasRelatedWork W2046613423 @default.
• W2892360355 hasRelatedWork W2048478956 @default.
• W2892360355 hasRelatedWork W2147491023 @default.

• next