FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2892360435> ?p ?o ?g. }

• W2892360435 endingPage "946" @default.
• W2892360435 startingPage "941" @default.
• W2892360435 abstract "Introduction: Sickle cell disease (SCD) is one of the most common monogenic diseases worldwide, affecting approximately 30 million people across the globe. It is one of the most common hemoglobinopathies affecting pregnancy, particularly in the black population. Pregnant women with SCD, in conjunction with the physiological changes of pregnancy, have an increased risk of developing severe maternal and fetal complications.Materials and methods: A descriptive, observational study was conducted retrospectively to determine the maternal and neonatal disease burden of pregnant women with SCD between 2011 and 2016. The study included pregnant patients with SCD admitted to the hospital, with confirmed diagnosis through hemoglobin electrophoresis. Patients having no confirmatory testing of the disease were excluded.Results: In all, 54% (34 patients) had no previous diagnosis of sickle cell anemia or presence of sickle cell trait, and so an in-hospital diagnosis was carried out through hemoglobin gel electrophoresis, whereas the remaining 46% (28 patients) had already a peripheral diagnosis. In total, the following profiles were obtained: Hb AS 62.9% (39 patients), Hb SC 17.7% (11 patients), Hb SS 16.1% (10 patients), Hb AC 3.2% (2 patients), and Hb CC 0% (0 patients). Vaso-occlusive pain crises constituted the most common cause of hospital admission antepartum (54.8% of the general population), occurring in 100% of the patients with Hb SS and Hb AC, in 45% of the Hb SC group and in 43% of those with the Hb AS trait. The second cause of hospital admission encompassed infectious processes, which affected 45% of the general population, 30% of the Hb AS group, 60% of the Hb SS group, 77% of the Hb SC group, and 100% of the Hb AC group. The method of termination of pregnancy of 44% (27 patients) was C-section. The most common perinatal complication was preterm birth, occurring in 26% (16 patients), with the highest incidence in the Hb AC group. The second most common complication was the intrauterine growth restriction, reported in 6% (4 patients) of all patients, being most frequently in the Hb SS group.Conclusion: Pregnant women having SCD should be assessed and managed by a multidisciplinary team composed of hematology, perinatology, and intensive care. Management should be conducted preferably in high-quality centers experienced in treating this entity, thereby decreasing the great impact of morbidity and mortality associated with SCD in the pregnant population." @default.
• W2892360435 created "2018-09-27" @default.
• W2892360435 creator A5073411027 @default.
• W2892360435 creator A5074993676 @default.
• W2892360435 creator A5075090243 @default.
• W2892360435 creator A5083076422 @default.
• W2892360435 creator A5083870511 @default.
• W2892360435 date "2018-09-19" @default.
• W2892360435 modified "2023-09-23" @default.
• W2892360435 title "Description of criteria for near miss in high-complexity obstetric population with sickle cell anemia: an observational study" @default.
• W2892360435 cites W1977082174 @default.
• W2892360435 cites W2004153714 @default.
• W2892360435 cites W2022869955 @default.
• W2892360435 cites W2025625762 @default.
• W2892360435 cites W2039029286 @default.
• W2892360435 cites W2046831466 @default.
• W2892360435 cites W2053495832 @default.
• W2892360435 cites W2063080769 @default.
• W2892360435 cites W2095099342 @default.
• W2892360435 cites W2114236784 @default.
• W2892360435 cites W2160848963 @default.
• W2892360435 cites W2176722137 @default.
• W2892360435 cites W4211186710 @default.
• W2892360435 cites W4244325282 @default.
• W2892360435 doi "https://doi.org/10.1080/14767058.2018.1510912" @default.
• W2892360435 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30231783" @default.
• W2892360435 hasPublicationYear "2018" @default.
• W2892360435 type Work @default.
• W2892360435 sameAs 2892360435 @default.
• W2892360435 citedByCount "2" @default.
• W2892360435 countsByYear W28923604352019 @default.
• W2892360435 countsByYear W28923604352023 @default.
• W2892360435 crossrefType "journal-article" @default.
• W2892360435 hasAuthorship W2892360435A5073411027 @default.
• W2892360435 hasAuthorship W2892360435A5074993676 @default.
• W2892360435 hasAuthorship W2892360435A5075090243 @default.
• W2892360435 hasAuthorship W2892360435A5083076422 @default.
• W2892360435 hasAuthorship W2892360435A5083870511 @default.
• W2892360435 hasConcept C126322002 @default.
• W2892360435 hasConcept C131872663 @default.
• W2892360435 hasConcept C187212893 @default.
• W2892360435 hasConcept C23131810 @default.
• W2892360435 hasConcept C2777566322 @default.
• W2892360435 hasConcept C2778063713 @default.
• W2892360435 hasConcept C2778248108 @default.
• W2892360435 hasConcept C2778620579 @default.
• W2892360435 hasConcept C2779134260 @default.
• W2892360435 hasConcept C2779234561 @default.
• W2892360435 hasConcept C2779668550 @default.
• W2892360435 hasConcept C2780976302 @default.
• W2892360435 hasConcept C2908647359 @default.
• W2892360435 hasConcept C54355233 @default.
• W2892360435 hasConcept C71924100 @default.
• W2892360435 hasConcept C86803240 @default.
• W2892360435 hasConcept C99454951 @default.
• W2892360435 hasConceptScore W2892360435C126322002 @default.
• W2892360435 hasConceptScore W2892360435C131872663 @default.
• W2892360435 hasConceptScore W2892360435C187212893 @default.
• W2892360435 hasConceptScore W2892360435C23131810 @default.
• W2892360435 hasConceptScore W2892360435C2777566322 @default.
• W2892360435 hasConceptScore W2892360435C2778063713 @default.
• W2892360435 hasConceptScore W2892360435C2778248108 @default.
• W2892360435 hasConceptScore W2892360435C2778620579 @default.
• W2892360435 hasConceptScore W2892360435C2779134260 @default.
• W2892360435 hasConceptScore W2892360435C2779234561 @default.
• W2892360435 hasConceptScore W2892360435C2779668550 @default.
• W2892360435 hasConceptScore W2892360435C2780976302 @default.
• W2892360435 hasConceptScore W2892360435C2908647359 @default.
• W2892360435 hasConceptScore W2892360435C54355233 @default.
• W2892360435 hasConceptScore W2892360435C71924100 @default.
• W2892360435 hasConceptScore W2892360435C86803240 @default.
• W2892360435 hasConceptScore W2892360435C99454951 @default.
• W2892360435 hasIssue "6" @default.
• W2892360435 hasLocation W28923604351 @default.
• W2892360435 hasLocation W28923604352 @default.
• W2892360435 hasOpenAccess W2892360435 @default.
• W2892360435 hasPrimaryLocation W28923604351 @default.
• W2892360435 hasRelatedWork W1990242487 @default.
• W2892360435 hasRelatedWork W2019805036 @default.
• W2892360435 hasRelatedWork W2069409292 @default.
• W2892360435 hasRelatedWork W2105072888 @default.
• W2892360435 hasRelatedWork W2156444983 @default.
• W2892360435 hasRelatedWork W2164577632 @default.
• W2892360435 hasRelatedWork W2892360435 @default.
• W2892360435 hasRelatedWork W3119704353 @default.
• W2892360435 hasRelatedWork W4206878687 @default.
• W2892360435 hasRelatedWork W4221155949 @default.
• W2892360435 hasVolume "33" @default.
• W2892360435 isParatext "false" @default.
• W2892360435 isRetracted "false" @default.
• W2892360435 magId "2892360435" @default.
• W2892360435 workType "article" @default.