Matches in SemOpenAlex for { <https://semopenalex.org/work/W2892380140> ?p ?o ?g. }
Showing items 1 to 66 of
66
with 100 items per page.
- W2892380140 abstract "e18542 Background: AHCT is the definitive treatment for AML with unfavorable risk however with increased morbidity and mortality limiting its use in adults above 60 years of age. National in patient sample (NIS) database was analyzed to study trends and predictors of mortality in AML patients receiving AHCT. Methods: NIS database includes 20% of all hospitalizations in USA. NIS database from 2010 - 2014 was analyzed. ICD-9 codes were used to extract patients and to analyze demography, comorbidities, complications and outcomes. A multivariable logistic regression was performed to identify predictors of mortality. Results: 1755 patients with AML and AHCT were identified from the database. Males 55.2%, median age 52, age >60 years 35%, Whites 80.6%, Blacks 5.5%, Hispanics 6.7% and others 7.2%. Median length of stay was 26 days. Inpatient mortality showed a decreasing trend from 2010 to 2014 (6.7%, 4.6%, 3.9%, 4.8%, 4.6%) likely due to better supportive care. p (trend) = 0.29. Univariate analysis for age >60 years did not show increase in mortality however multivariate analysis did show increase in mortality (Odds ratio 2.281, p = 0.006). Other predictive factors of increased mortality were presence of complications of AHCT. Infection (OR 8.392, p < 0.001), acute graft versus host disease (GVHD) (OR 2.139, p = 0.033) and pneumonia (OR 3.584, p <0.001) were associated with increased mortality. Independent predictive factors of mortality were renal failure (OR 14.186, p < 0.001) and liver disease (OR 3.228, p < 0.001). Conclusions: Age more than 60 by itself is not associated with increased mortality in the absence of complications and comorbidities. Infection is a major predictor of mortality. [Table: see text]" @default.
- W2892380140 created "2018-09-27" @default.
- W2892380140 creator A5030737561 @default.
- W2892380140 creator A5071002833 @default.
- W2892380140 date "2017-05-20" @default.
- W2892380140 modified "2023-09-27" @default.
- W2892380140 title "Nationwide in hospital outcomes of allogenic hematopoietic cell transplant (AHCT) in acute myeloid leukemia (AML)." @default.
- W2892380140 doi "https://doi.org/10.1200/jco.2017.35.15_suppl.e18542" @default.
- W2892380140 hasPublicationYear "2017" @default.
- W2892380140 type Work @default.
- W2892380140 sameAs 2892380140 @default.
- W2892380140 citedByCount "0" @default.
- W2892380140 crossrefType "journal-article" @default.
- W2892380140 hasAuthorship W2892380140A5030737561 @default.
- W2892380140 hasAuthorship W2892380140A5071002833 @default.
- W2892380140 hasConcept C109159458 @default.
- W2892380140 hasConcept C126322002 @default.
- W2892380140 hasConcept C143998085 @default.
- W2892380140 hasConcept C203014093 @default.
- W2892380140 hasConcept C2778461978 @default.
- W2892380140 hasConcept C2778729363 @default.
- W2892380140 hasConcept C2779282312 @default.
- W2892380140 hasConcept C28328180 @default.
- W2892380140 hasConcept C2993713153 @default.
- W2892380140 hasConcept C54355233 @default.
- W2892380140 hasConcept C71924100 @default.
- W2892380140 hasConcept C86803240 @default.
- W2892380140 hasConceptScore W2892380140C109159458 @default.
- W2892380140 hasConceptScore W2892380140C126322002 @default.
- W2892380140 hasConceptScore W2892380140C143998085 @default.
- W2892380140 hasConceptScore W2892380140C203014093 @default.
- W2892380140 hasConceptScore W2892380140C2778461978 @default.
- W2892380140 hasConceptScore W2892380140C2778729363 @default.
- W2892380140 hasConceptScore W2892380140C2779282312 @default.
- W2892380140 hasConceptScore W2892380140C28328180 @default.
- W2892380140 hasConceptScore W2892380140C2993713153 @default.
- W2892380140 hasConceptScore W2892380140C54355233 @default.
- W2892380140 hasConceptScore W2892380140C71924100 @default.
- W2892380140 hasConceptScore W2892380140C86803240 @default.
- W2892380140 hasLocation W28923801401 @default.
- W2892380140 hasOpenAccess W2892380140 @default.
- W2892380140 hasPrimaryLocation W28923801401 @default.
- W2892380140 hasRelatedWork W2028885925 @default.
- W2892380140 hasRelatedWork W2066429542 @default.
- W2892380140 hasRelatedWork W2110430549 @default.
- W2892380140 hasRelatedWork W2136459700 @default.
- W2892380140 hasRelatedWork W2159487206 @default.
- W2892380140 hasRelatedWork W2343365183 @default.
- W2892380140 hasRelatedWork W2519895987 @default.
- W2892380140 hasRelatedWork W2614005643 @default.
- W2892380140 hasRelatedWork W2633117067 @default.
- W2892380140 hasRelatedWork W2736181454 @default.
- W2892380140 hasRelatedWork W2806145169 @default.
- W2892380140 hasRelatedWork W2890736416 @default.
- W2892380140 hasRelatedWork W2898299468 @default.
- W2892380140 hasRelatedWork W2907510761 @default.
- W2892380140 hasRelatedWork W2980498819 @default.
- W2892380140 hasRelatedWork W2995911232 @default.
- W2892380140 hasRelatedWork W3094783376 @default.
- W2892380140 hasRelatedWork W3168387337 @default.
- W2892380140 hasRelatedWork W3198297985 @default.
- W2892380140 hasRelatedWork W3210696775 @default.
- W2892380140 isParatext "false" @default.
- W2892380140 isRetracted "false" @default.
- W2892380140 magId "2892380140" @default.
- W2892380140 workType "article" @default.