Matches in SemOpenAlex for { <https://semopenalex.org/work/W2892392616> ?p ?o ?g. }
- W2892392616 endingPage "212" @default.
- W2892392616 startingPage "204" @default.
- W2892392616 abstract "Hemolymph coagulation is among the major arms of the humoral immune response in crustaceans. According to the current model, hemolymph clotting in decapod crustacean relies mostly on the polymerization of the plasmatic clotting protein (CP) which is directly promoted by calcium-depended transglutaminase (TGase) released from hemocytes upon microbial stimulus or injury. However, the type of hemocytes containing TGase, and hence how the TGase is released, might vary among species. Thus, we discourse here about possible mechanisms for clotting initiation. On the other hand, the initiation of coagulation reaction in the absence of microbial elicitors is poorly understood and seems to involve hemocytes lability, yet the mechanism remains unknown. A cellular clottable protein called coagulogen, different to the plasma CP, occurs in several species and could be related with the immune response, but the biological relevance of this protein is unknown. It is also demonstrated that the clotting response is actively involved in defense against pathogens. In addition, both TGase and the CP show pleiotropic functions, and although both proteins are relatively conserved, some of their physic-chemical properties vary significantly. The occurrence of differences in the clotting system in crustaceans is conceivable given the high number of species and their diverse ecology. Results from still non-studied decapods may provide explanation for some of the issues presented here from an evolutionary perspective." @default.
- W2892392616 created "2018-10-05" @default.
- W2892392616 creator A5003010820 @default.
- W2892392616 creator A5007185875 @default.
- W2892392616 creator A5074215548 @default.
- W2892392616 date "2019-01-01" @default.
- W2892392616 modified "2023-10-18" @default.
- W2892392616 title "The clotting system in decapod crustaceans: History, current knowledge and what we need to know beyond the models" @default.
- W2892392616 cites W110756409 @default.
- W2892392616 cites W123332891 @default.
- W2892392616 cites W1527634600 @default.
- W2892392616 cites W1550722396 @default.
- W2892392616 cites W1589817245 @default.
- W2892392616 cites W1917614215 @default.
- W2892392616 cites W1963805491 @default.
- W2892392616 cites W1966175972 @default.
- W2892392616 cites W1967383434 @default.
- W2892392616 cites W1967455040 @default.
- W2892392616 cites W1967791947 @default.
- W2892392616 cites W1968357366 @default.
- W2892392616 cites W1969157447 @default.
- W2892392616 cites W1969406879 @default.
- W2892392616 cites W1969492968 @default.
- W2892392616 cites W1969518214 @default.
- W2892392616 cites W1973237176 @default.
- W2892392616 cites W1976303883 @default.
- W2892392616 cites W1976629146 @default.
- W2892392616 cites W1977232348 @default.
- W2892392616 cites W1977363450 @default.
- W2892392616 cites W1981795204 @default.
- W2892392616 cites W1981981460 @default.
- W2892392616 cites W1982404464 @default.
- W2892392616 cites W1984062937 @default.
- W2892392616 cites W1985636788 @default.
- W2892392616 cites W1985852955 @default.
- W2892392616 cites W1986852449 @default.
- W2892392616 cites W1992249145 @default.
- W2892392616 cites W1993181722 @default.
- W2892392616 cites W1994397872 @default.
- W2892392616 cites W1994657043 @default.
- W2892392616 cites W1995304960 @default.
- W2892392616 cites W1996775576 @default.
- W2892392616 cites W1998187051 @default.
- W2892392616 cites W1999570110 @default.
- W2892392616 cites W2000319971 @default.
- W2892392616 cites W2006666475 @default.
- W2892392616 cites W2010483260 @default.
- W2892392616 cites W2011883618 @default.
- W2892392616 cites W2013924209 @default.
- W2892392616 cites W2016019475 @default.
- W2892392616 cites W2016066703 @default.
- W2892392616 cites W2016951742 @default.
- W2892392616 cites W2017482741 @default.
- W2892392616 cites W2017599181 @default.
- W2892392616 cites W2017755126 @default.
- W2892392616 cites W2018088387 @default.
- W2892392616 cites W2019681881 @default.
- W2892392616 cites W2020750760 @default.
- W2892392616 cites W2021636615 @default.
- W2892392616 cites W2022733092 @default.
- W2892392616 cites W2022774233 @default.
- W2892392616 cites W2023183761 @default.
- W2892392616 cites W2024881274 @default.
- W2892392616 cites W2025461169 @default.
- W2892392616 cites W2025977227 @default.
- W2892392616 cites W2027010799 @default.
- W2892392616 cites W2029295217 @default.
- W2892392616 cites W2030458379 @default.
- W2892392616 cites W2035164647 @default.
- W2892392616 cites W2035884856 @default.
- W2892392616 cites W2037213211 @default.
- W2892392616 cites W2037756957 @default.
- W2892392616 cites W2039719605 @default.
- W2892392616 cites W2040943150 @default.
- W2892392616 cites W2041101035 @default.
- W2892392616 cites W2042704633 @default.
- W2892392616 cites W2044030167 @default.
- W2892392616 cites W2045288057 @default.
- W2892392616 cites W2045676586 @default.
- W2892392616 cites W2046426682 @default.
- W2892392616 cites W2046855535 @default.
- W2892392616 cites W2047395071 @default.
- W2892392616 cites W2051382632 @default.
- W2892392616 cites W2056276367 @default.
- W2892392616 cites W2059615484 @default.
- W2892392616 cites W2060401757 @default.
- W2892392616 cites W2065368736 @default.
- W2892392616 cites W2065635384 @default.
- W2892392616 cites W2066179008 @default.
- W2892392616 cites W2068105214 @default.
- W2892392616 cites W2071029577 @default.
- W2892392616 cites W2071245858 @default.
- W2892392616 cites W2075816155 @default.
- W2892392616 cites W2080724573 @default.
- W2892392616 cites W2081478396 @default.
- W2892392616 cites W2082657225 @default.
- W2892392616 cites W2089519110 @default.
- W2892392616 cites W2089780793 @default.