Matches in SemOpenAlex for { <https://semopenalex.org/work/W2892406429> ?p ?o ?g. }
- W2892406429 abstract "Cell division and death can be regulated by the mechanical forces within a tissue. We study the consequences for the stability and roughness of a propagating interface, by analysing a model of mechanically-regulated tissue growth in the regime of small driving forces. For an interface driven by homeostatic pressure imbalance or leader-cell motility, long and intermediate-wavelength instabilities arise, depending respectively on an effective viscosity of cell number change, and on substrate friction. A further mechanism depends on the strength of directed motility forces acting in the bulk. We analyse the fluctuations of a stable interface subjected to cell-level stochasticity, and find that mechanical feedback can help preserve reproducibility at the tissue scale. Our results elucidate mechanisms that could be important for orderly interface motion in developing tissues." @default.
- W2892406429 created "2018-10-05" @default.
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- W2892406429 date "2018-12-07" @default.
- W2892406429 modified "2023-10-16" @default.
- W2892406429 title "Stability and Roughness of Interfaces in Mechanically Regulated Tissues" @default.
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- W2892406429 doi "https://doi.org/10.1103/physrevlett.121.238102" @default.
- W2892406429 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6420071" @default.
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