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• W2892410905 abstract "The photoinduced disconnection of an oxazine heterocycle from a borondipyrromethene (BODIPY) chromophore activates bright far-red fluorescence. The high brightness of the product and the lack of autofluorescence in this spectral region allow its detection at the single-molecule level within the organelles of live cells. Indeed, these photoactivatable fluorophores localize in lysosomal compartments and remain covalently immobilized within these organelles. The suppression of diffusion allows the reiterative reconstruction of subdiffraction images and the visualization of the labeled organelles with excellent localization precision. Thus, the combination of photochemical, photophysical and structural properties designed into our fluorophores enable the visualization of live cells with a spatial resolution that is inaccessible to conventional fluorescence imaging." @default.
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• W2892410905 date "2018-09-24" @default.
• W2892410905 modified "2023-10-17" @default.
• W2892410905 title "Far-Red Photoactivatable BODIPYs for the Super-Resolution Imaging of Live Cells" @default.
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• W2892410905 doi "https://doi.org/10.1021/jacs.8b09099" @default.
• W2892410905 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30247890" @default.
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