FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2892422318> ?p ?o ?g. }

• W2892422318 endingPage "130" @default.
• W2892422318 startingPage "1" @default.
• W2892422318 abstract "Background Depression is the most prevalent mental health problem among people with learning disabilities. Objective The trial investigated the clinical effectiveness and cost-effectiveness of behavioural activation for depression experienced by people with mild to moderate learning disabilities. The intervention was compared with a guided self-help intervention. Design A multicentre, single-blind, randomised controlled trial, with follow-up at 4, 8 and 12 months post randomisation. There was a nested qualitative study. Setting Participants were recruited from community learning disability teams and services and from Improving Access to Psychological Therapies services in Scotland, England and Wales. Participants Participants were aged ≥ 18 years, with clinically significant depression, assessed using the Diagnostic Criteria for Psychiatric Disorders for use with Adults with Learning Disabilities. Participants had to be able to give informed consent and a supporter could accompany them to therapy. Interventions BeatIt was a manualised behavioural activation intervention, adapted for people with learning disabilities and depression. StepUp was an adapted guided self-help intervention. Main outcome measures The primary outcome measure was the Glasgow Depression Scale for people with a Learning Disability (GDS-LD). Secondary outcomes included carer ratings of depressive symptoms and aggressiveness, self-reporting of anxiety symptoms, social support, activity and adaptive behaviour, relationships, quality of life (QoL) and life events, and resource and medication use. Results There were 161 participants randomised (BeatIt, n = 84; StepUp, n = 77). Participant retention was strong, with 141 completing the trial. Most completed therapy (BeatIt: 86%; StepUp: 82%). At baseline, 63% of BeatIt participants and 66% of StepUp participants were prescribed antidepressants. There was no statistically significant difference in GDS-LD scores between the StepUp (12.94 points) and BeatIt (11.91 points) groups at the 12-month primary outcome point. However, both groups improved during the trial. Other psychological and QoL outcomes followed a similar pattern. There were no treatment group differences, but there was improvement in both groups. There was no economic evidence suggesting that BeatIt may be more cost-effective than StepUp. However, treatment costs for both groups were approximately only 4–6.5% of the total support costs. Results of the qualitative research with participants, supporters and therapists were in concert with the quantitative findings. Both treatments were perceived as active interventions and were valued in terms of their structure, content and perceived impact. Limitations A significant limitation was the absence of a treatment-as-usual (TAU) comparison. Conclusions Primary and secondary outcomes, economic data and qualitative results all clearly demonstrate that there was no evidence for BeatIt being more effective than StepUp. Future work Comparisons against TAU are required to determine whether or not these interventions had any effect. Trial registration Current Controlled Trials ISRCTN09753005. Funding This project was funded by the National Institute for Health Research Health Technology Assessment programme and will be published in full in Health Technology Assessment ; Vol. 22, No. 53. See the NIHR Journals Library website for further project information." @default.
• W2892422318 created "2018-10-05" @default.
• W2892422318 creator A5000203906 @default.
• W2892422318 creator A5010029981 @default.
• W2892422318 creator A5017361282 @default.
• W2892422318 creator A5019479654 @default.
• W2892422318 creator A5023031370 @default.
• W2892422318 creator A5023207853 @default.
• W2892422318 creator A5028807875 @default.
• W2892422318 creator A5031942118 @default.
• W2892422318 creator A5033059325 @default.
• W2892422318 creator A5042956899 @default.
• W2892422318 creator A5043849805 @default.
• W2892422318 creator A5056917826 @default.
• W2892422318 creator A5075101061 @default.
• W2892422318 creator A5078354802 @default.
• W2892422318 creator A5083558965 @default.
• W2892422318 creator A5088973528 @default.
• W2892422318 creator A5090549621 @default.
• W2892422318 date "2018-09-01" @default.
• W2892422318 modified "2023-10-12" @default.
• W2892422318 title "Behavioural activation versus guided self-help for depression in adults with learning disabilities: the BeatIt RCT" @default.
• W2892422318 cites W1495377470 @default.
• W2892422318 cites W1529629883 @default.
• W2892422318 cites W1547141139 @default.
• W2892422318 cites W1821386307 @default.
• W2892422318 cites W1833779814 @default.
• W2892422318 cites W1834156875 @default.
• W2892422318 cites W1919426323 @default.
• W2892422318 cites W1945794617 @default.
• W2892422318 cites W1963809540 @default.
• W2892422318 cites W1964823526 @default.
• W2892422318 cites W1964940767 @default.
• W2892422318 cites W1972433687 @default.
• W2892422318 cites W1974434493 @default.
• W2892422318 cites W1976770755 @default.
• W2892422318 cites W1985542720 @default.
• W2892422318 cites W1994222210 @default.
• W2892422318 cites W2001488856 @default.
• W2892422318 cites W2007124706 @default.
• W2892422318 cites W2020054800 @default.
• W2892422318 cites W2020279836 @default.
• W2892422318 cites W2021466207 @default.
• W2892422318 cites W2022282817 @default.
• W2892422318 cites W2022460519 @default.
• W2892422318 cites W2024205358 @default.
• W2892422318 cites W2028360313 @default.
• W2892422318 cites W2029997282 @default.
• W2892422318 cites W2031721549 @default.
• W2892422318 cites W2038150858 @default.
• W2892422318 cites W2040986019 @default.
• W2892422318 cites W2062098404 @default.
• W2892422318 cites W2065777413 @default.
• W2892422318 cites W2066400648 @default.
• W2892422318 cites W2068787463 @default.
• W2892422318 cites W2074080213 @default.
• W2892422318 cites W2077536131 @default.
• W2892422318 cites W2085884574 @default.
• W2892422318 cites W2088040467 @default.
• W2892422318 cites W2093020440 @default.
• W2892422318 cites W2096110875 @default.
• W2892422318 cites W2100304883 @default.
• W2892422318 cites W2110327306 @default.
• W2892422318 cites W2111178588 @default.
• W2892422318 cites W2113302965 @default.
• W2892422318 cites W2117994084 @default.
• W2892422318 cites W2124118357 @default.
• W2892422318 cites W2124189712 @default.
• W2892422318 cites W2125885438 @default.
• W2892422318 cites W2127110772 @default.
• W2892422318 cites W2127571361 @default.
• W2892422318 cites W2128603490 @default.
• W2892422318 cites W2128905238 @default.
• W2892422318 cites W2138093615 @default.
• W2892422318 cites W2138771616 @default.
• W2892422318 cites W2140815719 @default.
• W2892422318 cites W2143280830 @default.
• W2892422318 cites W2143371285 @default.
• W2892422318 cites W2146200755 @default.
• W2892422318 cites W2148602524 @default.
• W2892422318 cites W2150229987 @default.
• W2892422318 cites W2150781870 @default.
• W2892422318 cites W2175521857 @default.
• W2892422318 cites W2219000239 @default.
• W2892422318 cites W2260776258 @default.
• W2892422318 cites W2341016926 @default.
• W2892422318 cites W2415043147 @default.
• W2892422318 cites W2479552531 @default.
• W2892422318 cites W2502560620 @default.
• W2892422318 cites W2575075382 @default.
• W2892422318 cites W4248854933 @default.
• W2892422318 cites W4254425256 @default.
• W2892422318 doi "https://doi.org/10.3310/hta22530" @default.
• W2892422318 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6187110" @default.
• W2892422318 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30265239" @default.
• W2892422318 hasPublicationYear "2018" @default.
• W2892422318 type Work @default.
• W2892422318 sameAs 2892422318 @default.

• next