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- W2892530868 abstract "Central odontogenic fibroma (COF) is an uncommon benign fibroblastic tumor with variable amounts of inactive-looking odontogenic epithelium. We report here 3 new cases of COF. The tumors occurred, in women with a mean age of 48 years, as asymptomatic swellings in the mandible (2 cases: one in the premolar region and the other posterior to the first molar) and in the posterior maxilla. Image exams revealed well-defined and expansive multilocular radiolucencies with tooth displacement. Gross features included irregular and whitish fibrous tissue intimately associated with tooth roots. Microscopically, 1 case was classified as epithelium-rich, whereas the other 2 cases as the granular cell variant and COF associated with central giant cell granuloma. All patients were submitted to conservative surgical treatments, with no signs of recurrence after an average of 10 months of follow-up. Oral pathologists should consider COF when evaluating apparently aggressive multilocular lesions, located in tooth-bearing areas in middle-aged women." @default.
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- W2892530868 date "2018-09-01" @default.
- W2892530868 modified "2023-10-12" @default.
- W2892530868 title "Central Odontogenic Fibroma: Report of Three New Cases" @default.
- W2892530868 doi "https://doi.org/10.1016/j.oooo.2018.02.263" @default.
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