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- W2892534427 abstract "The field of immunoengineering aims to develop novel therapies and modern vaccines to manipulate and modulate the immune system and applies innovative technologies towards improved understanding of the immune system in health and disease. Microfluidics has proven to be an excellent technology for analytics in biology and chemistry. From simple microsystem chips to complex microfluidic designs, these platforms have witnessed an immense growth over the last decades with frequent emergence of new designs. Microfluidics provides a highly robust and precise tool which led to its widespread application in single-cell analysis of immune cells. Single-cell analysis allows scientists to account for the heterogeneous behaviour of immune cells which often gets overshadowed when conventional bulk study methods are used. Application of single-cell analysis using microfluidics has facilitated the identification of several novel functional immune cell subsets, quantification of signalling molecules, and understanding of cellular communication and signalling pathways. Single-cell analysis research in combination with microfluidics has paved the way for the development of novel therapies, point-of-care diagnostics, and even more complex microfluidic platforms that aid in creating in vitro cellular microenvironments for applications in drug and toxicity screening. In this review, we provide a comprehensive overview on the integration of microsystems and microfluidics with immunology and focus on different designs developed to decode single immune cell behaviour and cellular communication. We have categorized the microfluidic designs in three specific categories: microfluidic chips with cell traps, valve-based microfluidics, and droplet microfluidics that have facilitated the ongoing research in the field of immunology at single-cell level." @default.
- W2892534427 created "2018-10-05" @default.
- W2892534427 creator A5019884665 @default.
- W2892534427 creator A5034677246 @default.
- W2892534427 creator A5080567634 @default.
- W2892534427 date "2018-10-16" @default.
- W2892534427 modified "2023-10-05" @default.
- W2892534427 title "Integrating Immunology and Microfluidics for Single Immune Cell Analysis" @default.
- W2892534427 cites W14713705 @default.
- W2892534427 cites W1480357432 @default.
- W2892534427 cites W1491815146 @default.
- W2892534427 cites W1493586912 @default.
- W2892534427 cites W1570272764 @default.
- W2892534427 cites W1600928734 @default.
- W2892534427 cites W160997531 @default.
- W2892534427 cites W1661614692 @default.
- W2892534427 cites W1857529586 @default.
- W2892534427 cites W1930598094 @default.
- W2892534427 cites W1959447435 @default.
- W2892534427 cites W1965288236 @default.
- W2892534427 cites W1967179899 @default.
- W2892534427 cites W1968354334 @default.
- W2892534427 cites W1971680669 @default.
- W2892534427 cites W1974658457 @default.
- W2892534427 cites W1975581000 @default.
- W2892534427 cites W1975920074 @default.
- W2892534427 cites W1977281284 @default.
- W2892534427 cites W1982900838 @default.
- W2892534427 cites W1983450178 @default.
- W2892534427 cites W1983524455 @default.
- W2892534427 cites W1987128447 @default.
- W2892534427 cites W1989551825 @default.
- W2892534427 cites W1992699637 @default.
- W2892534427 cites W1992741965 @default.
- W2892534427 cites W1993294045 @default.
- W2892534427 cites W1997632704 @default.
- W2892534427 cites W1998350666 @default.
- W2892534427 cites W2001607419 @default.
- W2892534427 cites W2002987322 @default.
- W2892534427 cites W2006139996 @default.
- W2892534427 cites W2006782731 @default.
- W2892534427 cites W2007592589 @default.
- W2892534427 cites W2007951680 @default.
- W2892534427 cites W2008524523 @default.
- W2892534427 cites W2010405672 @default.
- W2892534427 cites W2010477093 @default.
- W2892534427 cites W2013077656 @default.
- W2892534427 cites W2015554529 @default.
- W2892534427 cites W2015671099 @default.
- W2892534427 cites W2016212824 @default.
- W2892534427 cites W2021005571 @default.
- W2892534427 cites W2024626836 @default.
- W2892534427 cites W2024971068 @default.
- W2892534427 cites W2027061207 @default.
- W2892534427 cites W2027168511 @default.
- W2892534427 cites W2032114606 @default.
- W2892534427 cites W2036050007 @default.
- W2892534427 cites W2037319473 @default.
- W2892534427 cites W2040629598 @default.
- W2892534427 cites W2043412200 @default.
- W2892534427 cites W2050547995 @default.
- W2892534427 cites W2053129129 @default.
- W2892534427 cites W2055565290 @default.
- W2892534427 cites W2056153476 @default.
- W2892534427 cites W2057237240 @default.
- W2892534427 cites W2060161472 @default.
- W2892534427 cites W2060929285 @default.
- W2892534427 cites W2062058852 @default.
- W2892534427 cites W2062811432 @default.
- W2892534427 cites W2062857909 @default.
- W2892534427 cites W2063896016 @default.
- W2892534427 cites W2067975406 @default.
- W2892534427 cites W2068190630 @default.
- W2892534427 cites W2069241164 @default.
- W2892534427 cites W2069828786 @default.
- W2892534427 cites W2070378283 @default.
- W2892534427 cites W2071010503 @default.
- W2892534427 cites W2072391169 @default.
- W2892534427 cites W2073256527 @default.
- W2892534427 cites W2074150439 @default.
- W2892534427 cites W2075456535 @default.
- W2892534427 cites W2078655054 @default.
- W2892534427 cites W2084726488 @default.
- W2892534427 cites W2085402152 @default.
- W2892534427 cites W2088047801 @default.
- W2892534427 cites W2089941945 @default.
- W2892534427 cites W2091702217 @default.
- W2892534427 cites W2092941484 @default.
- W2892534427 cites W2094381636 @default.
- W2892534427 cites W2094468773 @default.
- W2892534427 cites W2095340238 @default.
- W2892534427 cites W2099316577 @default.
- W2892534427 cites W2102212449 @default.
- W2892534427 cites W2104156313 @default.
- W2892534427 cites W2108872576 @default.
- W2892534427 cites W2112667541 @default.
- W2892534427 cites W2113065220 @default.
- W2892534427 cites W2119475668 @default.
- W2892534427 cites W2120566745 @default.
- W2892534427 cites W2122309838 @default.