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- W2892613148 abstract "Inflammatory bowel disease, ulcerative colitis, and Crohn disease may be induced by combined interactions of dysregulated immune reaction, environmental factors, and disease susceptibility genes. In normal conditions, reactive oxygen species play an important role in protecting the body from invading microorganisms. However, excessive production of ROS, mainly by neutrophils and macrophages in the intestinal mucosa, may play a role in the pathogenesis of inflammatory bowel disease. Antioxidants including polyphenols have been found to be effective for ameliorating the experimental colitis. Study on animal experimental colitis showed polyphenols’ effectiveness for inflammatory bowel diseases in three mechanisms: antioxidants, immunosuppressants, and ameliorating intestinal flora. Thus, curcumin, green tea (epigallocatechin-3-gallate-rich polyphenon E), bilberry anthocyanins, wheat grass juice, resveratrol, superoxide dismutase, and fish oils were shown to be effective in part for the treatment of human inflammatory bowel disease." @default.
- W2892613148 created "2018-10-05" @default.
- W2892613148 creator A5060829670 @default.
- W2892613148 creator A5081225839 @default.
- W2892613148 date "2018-01-01" @default.
- W2892613148 modified "2023-09-26" @default.
- W2892613148 title "Antioxidants and Polyphenols in Inflammatory Bowel Disease: Ulcerative Colitis and Crohn Disease" @default.
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- W2892613148 doi "https://doi.org/10.1016/b978-0-12-813008-7.00023-0" @default.
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