Matches in SemOpenAlex for { <https://semopenalex.org/work/W2892617059> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W2892617059 endingPage "1397" @default.
- W2892617059 startingPage "1386" @default.
- W2892617059 abstract "A new kind of magnetic gelatin-encapsulated nanoassembly was fabricated as a multifunctional drug delivery system (DDS) with pH, redox, and enzyme stimuli-responsive drug release for cancer theranostics. Cystamine-modified gelatin was used to encapsulate doxorubicin (Dox) as an anticancer drug and Fe₃O₄ as the magnetic resonance imaging (MRI) contrast agent to assembly into a nanoassembly via the formation of an oil-in-water microemulsion. Such a DDS system can provide long-term Dox release and more effective drug availability, since the acidic environment, high glutathione (GSH) and matrix metalloproteinase (MMP) level of cancer tissues. And it would beneficial for high accumulation around tumor through the enhanced penetration and retention (EPR) effect, and deeper penetration into tumor because of its enzyme-degradable and size-changeable ability. This drug delivery vehicle had good biocompatibility. It can effectively reduce the efflux of drugs when these nanoparticles were uptaken by cells. Besides, the Dox-Fe₃O₄@gelatin nanoparticles can be a contrast agent for T₂-weighted MRI." @default.
- W2892617059 created "2018-10-05" @default.
- W2892617059 creator A5000927257 @default.
- W2892617059 creator A5011894823 @default.
- W2892617059 creator A5057019913 @default.
- W2892617059 creator A5058246931 @default.
- W2892617059 creator A5060700361 @default.
- W2892617059 creator A5065257906 @default.
- W2892617059 creator A5083247969 @default.
- W2892617059 date "2017-11-01" @default.
- W2892617059 modified "2023-10-18" @default.
- W2892617059 title "Gelatin-Encapsulated Magnetic Nanoparticles for pH, Redox, and Enzyme Multiple Stimuli-Responsive Drug Delivery and Magnetic Resonance Imaging" @default.
- W2892617059 doi "https://doi.org/10.1166/jbn.2017.2433" @default.
- W2892617059 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31271126" @default.
- W2892617059 hasPublicationYear "2017" @default.
- W2892617059 type Work @default.
- W2892617059 sameAs 2892617059 @default.
- W2892617059 citedByCount "26" @default.
- W2892617059 countsByYear W28926170592018 @default.
- W2892617059 countsByYear W28926170592019 @default.
- W2892617059 countsByYear W28926170592020 @default.
- W2892617059 countsByYear W28926170592021 @default.
- W2892617059 countsByYear W28926170592022 @default.
- W2892617059 countsByYear W28926170592023 @default.
- W2892617059 crossrefType "journal-article" @default.
- W2892617059 hasAuthorship W2892617059A5000927257 @default.
- W2892617059 hasAuthorship W2892617059A5011894823 @default.
- W2892617059 hasAuthorship W2892617059A5057019913 @default.
- W2892617059 hasAuthorship W2892617059A5058246931 @default.
- W2892617059 hasAuthorship W2892617059A5060700361 @default.
- W2892617059 hasAuthorship W2892617059A5065257906 @default.
- W2892617059 hasAuthorship W2892617059A5083247969 @default.
- W2892617059 hasConcept C12554922 @default.
- W2892617059 hasConcept C141071460 @default.
- W2892617059 hasConcept C155672457 @default.
- W2892617059 hasConcept C171250308 @default.
- W2892617059 hasConcept C185592680 @default.
- W2892617059 hasConcept C192562407 @default.
- W2892617059 hasConcept C2776694085 @default.
- W2892617059 hasConcept C2778823387 @default.
- W2892617059 hasConcept C2779820397 @default.
- W2892617059 hasConcept C2781159505 @default.
- W2892617059 hasConcept C2781303535 @default.
- W2892617059 hasConcept C55493867 @default.
- W2892617059 hasConcept C71924100 @default.
- W2892617059 hasConcept C86803240 @default.
- W2892617059 hasConcept C87023908 @default.
- W2892617059 hasConceptScore W2892617059C12554922 @default.
- W2892617059 hasConceptScore W2892617059C141071460 @default.
- W2892617059 hasConceptScore W2892617059C155672457 @default.
- W2892617059 hasConceptScore W2892617059C171250308 @default.
- W2892617059 hasConceptScore W2892617059C185592680 @default.
- W2892617059 hasConceptScore W2892617059C192562407 @default.
- W2892617059 hasConceptScore W2892617059C2776694085 @default.
- W2892617059 hasConceptScore W2892617059C2778823387 @default.
- W2892617059 hasConceptScore W2892617059C2779820397 @default.
- W2892617059 hasConceptScore W2892617059C2781159505 @default.
- W2892617059 hasConceptScore W2892617059C2781303535 @default.
- W2892617059 hasConceptScore W2892617059C55493867 @default.
- W2892617059 hasConceptScore W2892617059C71924100 @default.
- W2892617059 hasConceptScore W2892617059C86803240 @default.
- W2892617059 hasConceptScore W2892617059C87023908 @default.
- W2892617059 hasIssue "11" @default.
- W2892617059 hasLocation W28926170591 @default.
- W2892617059 hasLocation W28926170592 @default.
- W2892617059 hasOpenAccess W2892617059 @default.
- W2892617059 hasPrimaryLocation W28926170591 @default.
- W2892617059 hasRelatedWork W170654718 @default.
- W2892617059 hasRelatedWork W1964537515 @default.
- W2892617059 hasRelatedWork W2064361807 @default.
- W2892617059 hasRelatedWork W2082380792 @default.
- W2892617059 hasRelatedWork W2257025148 @default.
- W2892617059 hasRelatedWork W2375178259 @default.
- W2892617059 hasRelatedWork W2401110990 @default.
- W2892617059 hasRelatedWork W2481087849 @default.
- W2892617059 hasRelatedWork W2749981827 @default.
- W2892617059 hasRelatedWork W2883611956 @default.
- W2892617059 hasVolume "13" @default.
- W2892617059 isParatext "false" @default.
- W2892617059 isRetracted "false" @default.
- W2892617059 magId "2892617059" @default.
- W2892617059 workType "article" @default.