FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2892647807> ?p ?o ?g. }

• W2892647807 endingPage "262" @default.
• W2892647807 startingPage "254" @default.
• W2892647807 abstract "Diabetes mellitus has not ceased to be on rise in spite of the continuous research on its management. Brain dysfunction associated with Diabetes mellitus especially Type II has been the great concern. The aim of this study was to investigate the effect of insulin sensitizing drug metformin and ethanolic extract of garlic on membrane bound enzymes Na+/K+ ATPase, Ca2+ ATPase and glutamate-glutamine cycle enzyme, Glutamine Synthetase activities in the hippocampus of streptozotocin-Nicotinamide induced Type II Diabetic rats. Twenty four male wistar rats weighted 120 - 150 g were used and divided into four groups with six rats in each group. Group A was non-diabetic (Control) and Groups B, C and D were diabetic. Group B received no treatment (DNT) while Groups C and D were treated with 1000 mg/kg of ethanolic garlic extract (EGE) and 50 mg/kg of metformin (MET) respectively orally for three weeks. All the groups were fed on standard rat chow with water ad libitum. Blood glucose was monitored weekly. Animals were sacrificed and the brains were removed and hippocampi were carefully excised and homogenate were obtained. Homogenate was analyzed for Na+/K+ ATPase, Ca2+ ATPase and Glutamine Synthetase (GS) activities. MET and EGE significantly reduced the blood glucose levels. There was a significant increase in the activities of hippocampal Na+/K+ ATPase, Ca2+ ATPase and GS in MET and EGE when compared to DNT. The results suggest that both MET and EGE increase the activities of hippocampal Na+/K+ ATPase, Ca2+ ATPase and GS which were reduced by diabetes mellitus, thus garlic and metformin administration exhibiting neuroprotective effect during hippocampal-related disorders associated with diabetes mellitus." @default.
• W2892647807 created "2018-10-05" @default.
• W2892647807 creator A5019902787 @default.
• W2892647807 creator A5026313033 @default.
• W2892647807 creator A5051638689 @default.
• W2892647807 creator A5056815789 @default.
• W2892647807 creator A5062925921 @default.
• W2892647807 creator A5070808572 @default.
• W2892647807 creator A5090966405 @default.
• W2892647807 creator A5082192700 @default.
• W2892647807 date "2018-01-01" @default.
• W2892647807 modified "2023-10-10" @default.
• W2892647807 title "Comparative Study of the Effects of Metformin and Garlic Extract on Hippocampal Na&lt;sup&gt;+&lt;/sup&gt;/K&lt;sup&gt;+&lt;/sup&gt; ATPase, Ca&lt;sup&gt;2+&lt;/sup&gt; ATPase and Glutamine Synthetase Activities in Type II Diabetic Wistar Rat" @default.
• W2892647807 cites W1423235038 @default.
• W2892647807 cites W1965653609 @default.
• W2892647807 cites W1984979932 @default.
• W2892647807 cites W2000479721 @default.
• W2892647807 cites W2006528374 @default.
• W2892647807 cites W2025507512 @default.
• W2892647807 cites W2031361091 @default.
• W2892647807 cites W2059606036 @default.
• W2892647807 cites W2065009648 @default.
• W2892647807 cites W2067657714 @default.
• W2892647807 cites W2086032754 @default.
• W2892647807 cites W2094109323 @default.
• W2892647807 cites W2128367294 @default.
• W2892647807 cites W2136331613 @default.
• W2892647807 cites W2147638059 @default.
• W2892647807 cites W2152826676 @default.
• W2892647807 cites W2153435210 @default.
• W2892647807 cites W2264936610 @default.
• W2892647807 cites W2336925368 @default.
• W2892647807 cites W2339427242 @default.
• W2892647807 cites W2374285893 @default.
• W2892647807 cites W2587325490 @default.
• W2892647807 cites W2780950571 @default.
• W2892647807 cites W2933668640 @default.
• W2892647807 doi "https://doi.org/10.4236/jbise.2018.119021" @default.
• W2892647807 hasPublicationYear "2018" @default.
• W2892647807 type Work @default.
• W2892647807 sameAs 2892647807 @default.
• W2892647807 citedByCount "3" @default.
• W2892647807 countsByYear W28926478072022 @default.
• W2892647807 countsByYear W28926478072023 @default.
• W2892647807 crossrefType "journal-article" @default.
• W2892647807 hasAuthorship W2892647807A5019902787 @default.
• W2892647807 hasAuthorship W2892647807A5026313033 @default.
• W2892647807 hasAuthorship W2892647807A5051638689 @default.
• W2892647807 hasAuthorship W2892647807A5056815789 @default.
• W2892647807 hasAuthorship W2892647807A5062925921 @default.
• W2892647807 hasAuthorship W2892647807A5070808572 @default.
• W2892647807 hasAuthorship W2892647807A5082192700 @default.
• W2892647807 hasAuthorship W2892647807A5090966405 @default.
• W2892647807 hasBestOaLocation W28926478071 @default.
• W2892647807 hasConcept C126322002 @default.
• W2892647807 hasConcept C134018914 @default.
• W2892647807 hasConcept C170493617 @default.
• W2892647807 hasConcept C181199279 @default.
• W2892647807 hasConcept C185592680 @default.
• W2892647807 hasConcept C23265538 @default.
• W2892647807 hasConcept C2779280383 @default.
• W2892647807 hasConcept C2779289688 @default.
• W2892647807 hasConcept C2779306644 @default.
• W2892647807 hasConcept C2779349466 @default.
• W2892647807 hasConcept C2779728014 @default.
• W2892647807 hasConcept C2780323712 @default.
• W2892647807 hasConcept C515207424 @default.
• W2892647807 hasConcept C55493867 @default.
• W2892647807 hasConcept C555293320 @default.
• W2892647807 hasConcept C61174792 @default.
• W2892647807 hasConcept C71924100 @default.
• W2892647807 hasConceptScore W2892647807C126322002 @default.
• W2892647807 hasConceptScore W2892647807C134018914 @default.
• W2892647807 hasConceptScore W2892647807C170493617 @default.
• W2892647807 hasConceptScore W2892647807C181199279 @default.
• W2892647807 hasConceptScore W2892647807C185592680 @default.
• W2892647807 hasConceptScore W2892647807C23265538 @default.
• W2892647807 hasConceptScore W2892647807C2779280383 @default.
• W2892647807 hasConceptScore W2892647807C2779289688 @default.
• W2892647807 hasConceptScore W2892647807C2779306644 @default.
• W2892647807 hasConceptScore W2892647807C2779349466 @default.
• W2892647807 hasConceptScore W2892647807C2779728014 @default.
• W2892647807 hasConceptScore W2892647807C2780323712 @default.
• W2892647807 hasConceptScore W2892647807C515207424 @default.
• W2892647807 hasConceptScore W2892647807C55493867 @default.
• W2892647807 hasConceptScore W2892647807C555293320 @default.
• W2892647807 hasConceptScore W2892647807C61174792 @default.
• W2892647807 hasConceptScore W2892647807C71924100 @default.
• W2892647807 hasIssue "09" @default.
• W2892647807 hasLocation W28926478071 @default.
• W2892647807 hasOpenAccess W2892647807 @default.
• W2892647807 hasPrimaryLocation W28926478071 @default.
• W2892647807 hasRelatedWork W1706803842 @default.
• W2892647807 hasRelatedWork W1978358780 @default.
• W2892647807 hasRelatedWork W2022749662 @default.
• W2892647807 hasRelatedWork W2037171804 @default.
• W2892647807 hasRelatedWork W2060794300 @default.
• W2892647807 hasRelatedWork W2114227454 @default.

• next