Matches in SemOpenAlex for { <https://semopenalex.org/work/W2892648968> ?p ?o ?g. }
- W2892648968 endingPage "65" @default.
- W2892648968 startingPage "59" @default.
- W2892648968 abstract "Background: Blood-brain permeability is the primary concern when dealing with the biodistribution of drugs to the brain in neurological diseases. Objective: The purpose of the study is to develop the nanoformulation of Epigallocatechin gallate (EGCG) in order to improve its bioavailability and penetration into the brain. Methods: EGCG loaded Solid Lipid Nanoparticles (SLNs) have been developed using microemulsification method and pharmacological assessments were performed. Results: Surface morphology and micromeritics analysis showed the successful development of EGCG loaded solid lipid nanoparticles with an average size of 162.4 nm and spherical in shape. In vitro release studies indicated a consistent and slow drug release. Pharmacological evaluation of SLN-EGCG demonstrated a significant improvement in cerebral ischemia-induced memory impairment. Conclusion: The results indicate that the EGCG loaded SLNs provide a potential drug delivery system for improved delivery of EGCG to the brain, hence, enhancing its brain bioavailability." @default.
- W2892648968 created "2018-10-05" @default.
- W2892648968 creator A5008948224 @default.
- W2892648968 creator A5017282213 @default.
- W2892648968 creator A5022950768 @default.
- W2892648968 creator A5031993756 @default.
- W2892648968 creator A5054669577 @default.
- W2892648968 creator A5070636863 @default.
- W2892648968 creator A5077593886 @default.
- W2892648968 creator A5083317302 @default.
- W2892648968 date "2018-11-27" @default.
- W2892648968 modified "2023-09-26" @default.
- W2892648968 title "A New Therapeutic Approach for Brain Delivery of Epigallocatechin Gallate: Development and Characterization Studies" @default.
- W2892648968 cites W1011046171 @default.
- W2892648968 cites W1564553363 @default.
- W2892648968 cites W1964896591 @default.
- W2892648968 cites W1974192740 @default.
- W2892648968 cites W1992967957 @default.
- W2892648968 cites W2005883397 @default.
- W2892648968 cites W2017317942 @default.
- W2892648968 cites W2018504340 @default.
- W2892648968 cites W2028687228 @default.
- W2892648968 cites W2044681516 @default.
- W2892648968 cites W2044903986 @default.
- W2892648968 cites W2055449190 @default.
- W2892648968 cites W2058411440 @default.
- W2892648968 cites W2065870072 @default.
- W2892648968 cites W2083172358 @default.
- W2892648968 cites W2094843360 @default.
- W2892648968 cites W2099879284 @default.
- W2892648968 cites W2114190473 @default.
- W2892648968 cites W2122755057 @default.
- W2892648968 cites W2125521135 @default.
- W2892648968 cites W2141162588 @default.
- W2892648968 cites W2146316728 @default.
- W2892648968 cites W2155606275 @default.
- W2892648968 cites W2351673993 @default.
- W2892648968 cites W2462161994 @default.
- W2892648968 cites W2475323102 @default.
- W2892648968 cites W2476373200 @default.
- W2892648968 doi "https://doi.org/10.2174/1567201815666180926121104" @default.
- W2892648968 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30255756" @default.
- W2892648968 hasPublicationYear "2018" @default.
- W2892648968 type Work @default.
- W2892648968 sameAs 2892648968 @default.
- W2892648968 citedByCount "6" @default.
- W2892648968 countsByYear W28926489682019 @default.
- W2892648968 countsByYear W28926489682020 @default.
- W2892648968 countsByYear W28926489682021 @default.
- W2892648968 countsByYear W28926489682022 @default.
- W2892648968 crossrefType "journal-article" @default.
- W2892648968 hasAuthorship W2892648968A5008948224 @default.
- W2892648968 hasAuthorship W2892648968A5017282213 @default.
- W2892648968 hasAuthorship W2892648968A5022950768 @default.
- W2892648968 hasAuthorship W2892648968A5031993756 @default.
- W2892648968 hasAuthorship W2892648968A5054669577 @default.
- W2892648968 hasAuthorship W2892648968A5070636863 @default.
- W2892648968 hasAuthorship W2892648968A5077593886 @default.
- W2892648968 hasAuthorship W2892648968A5083317302 @default.
- W2892648968 hasConcept C112705442 @default.
- W2892648968 hasConcept C171250308 @default.
- W2892648968 hasConcept C181389837 @default.
- W2892648968 hasConcept C185592680 @default.
- W2892648968 hasConcept C192562407 @default.
- W2892648968 hasConcept C199529486 @default.
- W2892648968 hasConcept C202751555 @default.
- W2892648968 hasConcept C2777192995 @default.
- W2892648968 hasConcept C2777807558 @default.
- W2892648968 hasConcept C2778004101 @default.
- W2892648968 hasConcept C2779820397 @default.
- W2892648968 hasConcept C2780035454 @default.
- W2892648968 hasConcept C55493867 @default.
- W2892648968 hasConcept C70899900 @default.
- W2892648968 hasConcept C71924100 @default.
- W2892648968 hasConcept C98274493 @default.
- W2892648968 hasConceptScore W2892648968C112705442 @default.
- W2892648968 hasConceptScore W2892648968C171250308 @default.
- W2892648968 hasConceptScore W2892648968C181389837 @default.
- W2892648968 hasConceptScore W2892648968C185592680 @default.
- W2892648968 hasConceptScore W2892648968C192562407 @default.
- W2892648968 hasConceptScore W2892648968C199529486 @default.
- W2892648968 hasConceptScore W2892648968C202751555 @default.
- W2892648968 hasConceptScore W2892648968C2777192995 @default.
- W2892648968 hasConceptScore W2892648968C2777807558 @default.
- W2892648968 hasConceptScore W2892648968C2778004101 @default.
- W2892648968 hasConceptScore W2892648968C2779820397 @default.
- W2892648968 hasConceptScore W2892648968C2780035454 @default.
- W2892648968 hasConceptScore W2892648968C55493867 @default.
- W2892648968 hasConceptScore W2892648968C70899900 @default.
- W2892648968 hasConceptScore W2892648968C71924100 @default.
- W2892648968 hasConceptScore W2892648968C98274493 @default.
- W2892648968 hasIssue "1" @default.
- W2892648968 hasLocation W28926489681 @default.
- W2892648968 hasLocation W28926489682 @default.
- W2892648968 hasOpenAccess W2892648968 @default.
- W2892648968 hasPrimaryLocation W28926489681 @default.
- W2892648968 hasRelatedWork W1555144605 @default.
- W2892648968 hasRelatedWork W1970245702 @default.