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- W2892654889 abstract "Abstract Background Portal cavernoma cholangiopathy ( PCC ), a surgical‐endoscopic dilemma, has not been studied comprehensively, more so in children. Our study aimed to evaluate PCC in children using a combination of magnetic resonance cholangiography‐portovenography ( MRC ‐ MRPV ) and endoscopic ultrasonography ( EUS ). Methods In this prospective cross‐sectional study, recruited children with extrahepatic portal venous obstruction ( EHPVO ) underwent MRC ‐ MRPV and radial array EUS . PCC was categorized as asymptomatic PCC , symptomatic and no‐ PCC . Modified Llop grading was used to grade the MRC changes. Results Sixty‐six of 72 (92%) children had PCC (85% asymptomatic; 7% symptomatic) on MRC . Age at study and duration of disease had significant correlation ( r = 0.588, P < 0.001). 63% had grade III MRC changes. MRC grades and superior mesenteric vein block (64%) on MRPV significantly corresponded with EUS changes (intracholedochal varices, choledochal perforators, intramural cholecystic collaterals and biliary calculi). Superior mesenteric vein non‐patency was a strong predictor of MRC biliary changes ( P = 0.003, odds ratio 46.4, 95% confidence interval 4.91–623.6). Conclusions A majority of EHPVO children have asymptomatic cholangiopathy and should be routinely evaluated for PCC at the time of first presentation by MRC ‐ MRPV . Additional superior mesenteric vein block with portal cavernoma results in significantly higher changes of cholangiopathy on MRC and EUS ." @default.
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- W2892654889 date "2018-10-01" @default.
- W2892654889 modified "2023-09-26" @default.
- W2892654889 title "Cholangiopathy in children with extrahepatic portal venous obstruction" @default.
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- W2892654889 doi "https://doi.org/10.1002/jhbp.582" @default.
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