Matches in SemOpenAlex for { <https://semopenalex.org/work/W2892657413> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2892657413 abstract "To determine the effect of hyaluronidase on time to onset and offset of anaesthesia in ropivacaine or bupivacaine femoral-ischiatic nerve blocks.Blinded randomized crossover trial.Eight dogs.Each dog underwent four treatments separated into two blocks - initially, the ropivacaine treatment block: RS (ropivacaine 0.5% plus saline 0.9%) and RH (ropivacaine 0.5% plus hyaluronidase 100 IU mL-1), followed 3 weeks later by the bupivacaine treatment block: BS (bupivacaine 0.5% plus saline) and BH (bupivacaine 0.5% plus hyaluronidase). The local anaesthetics were administered at 0.1 mL kg-1 per site. Hyaluronidase and saline were administered at 0.02 mL kg-1 per site. Performance of femoral-ischiatic blocks was aided by a combined ultrasound-electrolocation technique. The mechanical nociceptive threshold was measured, until offset or 360 minutes, using an algometer to ascertain baseline, onset and offset of anaesthesia. Onset and offset of anaesthesia were defined as a 25% increase above and as a return to <25% above baseline nociceptive threshold readings, respectively.The median (range) onset of anaesthesia for RS and RH was 21 (3-60) and 12 (3-21) minutes, respectively (p = 0.141), and offset was 270 (90-360) and 180 (30-300) minutes, respectively (p = 0.361). By contrast, the median (range) onset of anaesthesia for BS and BH was 24 (3-60) and 9 (3-27) minutes, respectively (p = 0.394), and offset was 360 (240-360) and 330 (210-360) minutes, respectively (p = 0.456).Hyaluronidase had no effect on the onset and offset times of ropivacaine and bupivacaine femoral-ischiatic nerve blocks in dogs compared with saline. The onset and offset times were highly variable in all treatments. Clinically, the high variability of the onset and offset times of the regional anaesthesia of these local anaesthetic drugs means that clinicians must monitor the animal's response and, if required, provide additional analgesic drugs." @default.
- W2892657413 created "2018-10-05" @default.
- W2892657413 creator A5046770744 @default.
- W2892657413 creator A5051818307 @default.
- W2892657413 creator A5060064973 @default.
- W2892657413 date "2019-03-01" @default.
- W2892657413 modified "2023-09-27" @default.
- W2892657413 title "Effects of hyaluronidase on ropivacaine or bupivacaine regional anaesthesia of the canine pelvic limb" @default.
- W2892657413 cites W1169343166 @default.
- W2892657413 cites W1575463177 @default.
- W2892657413 cites W1612551895 @default.
- W2892657413 cites W1867402696 @default.
- W2892657413 cites W1901834802 @default.
- W2892657413 cites W1916538716 @default.
- W2892657413 cites W1973507061 @default.
- W2892657413 cites W1975352023 @default.
- W2892657413 cites W1975661375 @default.
- W2892657413 cites W1991715883 @default.
- W2892657413 cites W1996153360 @default.
- W2892657413 cites W1997130850 @default.
- W2892657413 cites W2014958702 @default.
- W2892657413 cites W2046408417 @default.
- W2892657413 cites W2058054209 @default.
- W2892657413 cites W2062947272 @default.
- W2892657413 cites W2080000287 @default.
- W2892657413 cites W2080905936 @default.
- W2892657413 cites W2104130452 @default.
- W2892657413 cites W2107994073 @default.
- W2892657413 cites W2127477506 @default.
- W2892657413 cites W2155389008 @default.
- W2892657413 cites W2156613664 @default.
- W2892657413 cites W2195133314 @default.
- W2892657413 cites W2601010434 @default.
- W2892657413 cites W2606141262 @default.
- W2892657413 cites W3609270 @default.
- W2892657413 doi "https://doi.org/10.1016/j.vaa.2018.09.041" @default.
- W2892657413 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30718077" @default.
- W2892657413 hasPublicationYear "2019" @default.
- W2892657413 type Work @default.
- W2892657413 sameAs 2892657413 @default.
- W2892657413 citedByCount "1" @default.
- W2892657413 countsByYear W28926574132022 @default.
- W2892657413 crossrefType "journal-article" @default.
- W2892657413 hasAuthorship W2892657413A5046770744 @default.
- W2892657413 hasAuthorship W2892657413A5051818307 @default.
- W2892657413 hasAuthorship W2892657413A5060064973 @default.
- W2892657413 hasConcept C126322002 @default.
- W2892657413 hasConcept C142724271 @default.
- W2892657413 hasConcept C15490471 @default.
- W2892657413 hasConcept C170493617 @default.
- W2892657413 hasConcept C181199279 @default.
- W2892657413 hasConcept C185592680 @default.
- W2892657413 hasConcept C204787440 @default.
- W2892657413 hasConcept C27081682 @default.
- W2892657413 hasConcept C2776983577 @default.
- W2892657413 hasConcept C2777397205 @default.
- W2892657413 hasConcept C2780269707 @default.
- W2892657413 hasConcept C2780375986 @default.
- W2892657413 hasConcept C2781328992 @default.
- W2892657413 hasConcept C42219234 @default.
- W2892657413 hasConcept C55493867 @default.
- W2892657413 hasConcept C71924100 @default.
- W2892657413 hasConcept C87813604 @default.
- W2892657413 hasConceptScore W2892657413C126322002 @default.
- W2892657413 hasConceptScore W2892657413C142724271 @default.
- W2892657413 hasConceptScore W2892657413C15490471 @default.
- W2892657413 hasConceptScore W2892657413C170493617 @default.
- W2892657413 hasConceptScore W2892657413C181199279 @default.
- W2892657413 hasConceptScore W2892657413C185592680 @default.
- W2892657413 hasConceptScore W2892657413C204787440 @default.
- W2892657413 hasConceptScore W2892657413C27081682 @default.
- W2892657413 hasConceptScore W2892657413C2776983577 @default.
- W2892657413 hasConceptScore W2892657413C2777397205 @default.
- W2892657413 hasConceptScore W2892657413C2780269707 @default.
- W2892657413 hasConceptScore W2892657413C2780375986 @default.
- W2892657413 hasConceptScore W2892657413C2781328992 @default.
- W2892657413 hasConceptScore W2892657413C42219234 @default.
- W2892657413 hasConceptScore W2892657413C55493867 @default.
- W2892657413 hasConceptScore W2892657413C71924100 @default.
- W2892657413 hasConceptScore W2892657413C87813604 @default.
- W2892657413 hasFunder F4320320671 @default.
- W2892657413 hasFunder F4320320692 @default.
- W2892657413 hasLocation W28926574131 @default.
- W2892657413 hasLocation W28926574132 @default.
- W2892657413 hasOpenAccess W2892657413 @default.
- W2892657413 hasPrimaryLocation W28926574131 @default.
- W2892657413 hasRelatedWork W1993741959 @default.
- W2892657413 hasRelatedWork W2004825434 @default.
- W2892657413 hasRelatedWork W2010112604 @default.
- W2892657413 hasRelatedWork W2018865514 @default.
- W2892657413 hasRelatedWork W2296136517 @default.
- W2892657413 hasRelatedWork W2333262593 @default.
- W2892657413 hasRelatedWork W2336167803 @default.
- W2892657413 hasRelatedWork W2409443654 @default.
- W2892657413 hasRelatedWork W2417266936 @default.
- W2892657413 hasRelatedWork W2885964801 @default.
- W2892657413 isParatext "false" @default.
- W2892657413 isRetracted "false" @default.
- W2892657413 magId "2892657413" @default.
- W2892657413 workType "article" @default.