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- W2892673575 abstract "Background: With the scale up of intra-domiciliary vector control interventions such as LLINs and IRS, major achievements have been made so far in vector control in terms of declining densities and reducing in malaria transmission. However, several challenges face these interventions including shifts in population compositions, changes in biting and resting behaviours, insecticide resistance and likelihood of species replacement. However, to significantly reduce malaria transmission, there need to explore ecologically sound strategies which will target the immature stages and empower communities in vector control implementation through environmental management. This study, explored the additional benefits of adding other vector control tools to the primary vector control (LLINs) in coastal Kenya. Method: A Randomised Cluster Trial design was used to cluster 16 villages into 4 study arms which included LLINs only, LLINs and Bti combination, LLINs, Bti and Community Education and Mobilization (CEM), and LLINs and CEM. During the study, 2013 was used as base year while interventions in the 4 arms were implemented in 2014 and 2015. Results: A total of 2,436 Anopheles and 4,175 Culicines were collected between 2013 and 2015 using CDC Light traps. The overall mean densities per trap per night was 1.63 and 2.79 for Anopheles and culicines respectively. Based on negative binomial Generalised Estimation Equation (GEE) model for Anopheles and Culex mosquitoes, there was reduction on densities in the 4 arms of the study. However, there was significant reduction (p= 0.035, Relative Risk (RR), 1.89 CI (1.04-3.42) in Anopheles mosquitoes in the LLINs and Bti combination compared to other interventions. Based on the model, LLINs, Bti and Community Education and Mobilization (CEM) arm and LLINs and CEM did not have significant reductive impact. Conclusion: It was observed that there were additional benefits for combining LLINs with larval based management strategy. Therefore, it would be important to additionally implement additional tools to safe guard the benefits so far achieved by LLINs. Kenya Medical Research Institute (KEMRI), Centre for Geographic Medicine Research Coast (CGMRC), P.O. Box 428 – 80108, Kilifi and Public Health Department, KEMRI-Wellcome Trust Research Program, Nairobi, Kenya" @default.
- W2892673575 created "2018-10-05" @default.
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- W2892673575 date "2017-06-21" @default.
- W2892673575 modified "2023-09-27" @default.
- W2892673575 title "Vector control strategies for sustainable malaria transmission management in Kenya" @default.
- W2892673575 hasPublicationYear "2017" @default.
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