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• W2892710900 endingPage "143" @default.
• W2892710900 startingPage "130" @default.
• W2892710900 abstract "The term ferroptosis was coined in 2012 to describe an iron-dependent regulated form of cell death caused by the accumulation of lipid-based reactive oxygen species; this type of cell death was found to have molecular characteristics distinct from other forms of regulated cell death. Features of ferroptosis have been observed periodically over the last several decades, but these molecular features were not recognized as evidence of a distinct form of cell death until recently. Here, we describe the history of observations consistent with the current definition of ferroptosis, as well as the advances that contributed to the emergence of the concept of ferroptosis. We also discuss recent implications and applications of manipulations of the ferroptotic death pathway." @default.
• W2892710900 created "2018-10-05" @default.
• W2892710900 creator A5030207693 @default.
• W2892710900 creator A5083671566 @default.
• W2892710900 date "2019-03-01" @default.
• W2892710900 modified "2023-10-18" @default.
• W2892710900 title "The development of the concept of ferroptosis" @default.
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