Matches in SemOpenAlex for { <https://semopenalex.org/work/W2892722467> ?p ?o ?g. }
- W2892722467 endingPage "64" @default.
- W2892722467 startingPage "52" @default.
- W2892722467 abstract "Although the role of endogenous mechanical stresses in regulating morphogenetic movements and cell differentiation is now well established, many aspects of mechanical stress generation and transmission in developing embryos remain unclear and require quantitative studies.By measuring stress-bearing linear deformations (caused by differences in cell movement rates) in the outer cell layer of blastula - early tail-bud Xenopus embryos, we revealed a set of long-term tension-generating gradients of cell movement rates, modulated by short-term cell-cell displacements much increasing the rates of local deformations. Experimental relaxation of tensions distorted the gradients but preserved and even enhanced local cell-cell displacements. During development, an incoherent mode of cell behavior, characterized by extensive cell-cell displacements and poorly correlated cell trajectories, was exchanged for a more coherent regime with the opposite characteristics. In particular, cell shifts became more synchronous and acquired a periodicity of several dozen minutes.Morphogenetic movements in Xenopus embryos are mediated by mechanically stressed dynamic structures of two different levels: extended gradients and short-term cell-cell displacements. As development proceeds, the latter component decreases and cell trajectories become more correlated. In particular, they acquire common periodicities, making morphogenesis more coherent." @default.
- W2892722467 created "2018-10-05" @default.
- W2892722467 creator A5004222902 @default.
- W2892722467 creator A5028416824 @default.
- W2892722467 creator A5089968080 @default.
- W2892722467 date "2018-11-01" @default.
- W2892722467 modified "2023-09-24" @default.
- W2892722467 title "Stress-generating tissue deformations in Xenopus embryos: Long-range gradients and local cell displacements" @default.
- W2892722467 cites W1018855955 @default.
- W2892722467 cites W1523685816 @default.
- W2892722467 cites W1814220150 @default.
- W2892722467 cites W1935882254 @default.
- W2892722467 cites W1971885142 @default.
- W2892722467 cites W1979614850 @default.
- W2892722467 cites W1980173692 @default.
- W2892722467 cites W1987817703 @default.
- W2892722467 cites W1998917946 @default.
- W2892722467 cites W2008179424 @default.
- W2892722467 cites W2030452120 @default.
- W2892722467 cites W2052265852 @default.
- W2892722467 cites W2058096164 @default.
- W2892722467 cites W2060897454 @default.
- W2892722467 cites W2069838915 @default.
- W2892722467 cites W2095121497 @default.
- W2892722467 cites W2097444304 @default.
- W2892722467 cites W2100667554 @default.
- W2892722467 cites W2110759931 @default.
- W2892722467 cites W2123046057 @default.
- W2892722467 cites W2127042577 @default.
- W2892722467 cites W2128135781 @default.
- W2892722467 cites W2131403581 @default.
- W2892722467 cites W2145699930 @default.
- W2892722467 cites W2147539132 @default.
- W2892722467 cites W2151103961 @default.
- W2892722467 cites W2161491446 @default.
- W2892722467 cites W2185371632 @default.
- W2892722467 cites W2585137695 @default.
- W2892722467 cites W2588123864 @default.
- W2892722467 cites W2606063864 @default.
- W2892722467 cites W2895586865 @default.
- W2892722467 cites W2952432038 @default.
- W2892722467 doi "https://doi.org/10.1016/j.biosystems.2018.09.017" @default.
- W2892722467 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30273637" @default.
- W2892722467 hasPublicationYear "2018" @default.
- W2892722467 type Work @default.
- W2892722467 sameAs 2892722467 @default.
- W2892722467 citedByCount "2" @default.
- W2892722467 countsByYear W28927224672018 @default.
- W2892722467 countsByYear W28927224672022 @default.
- W2892722467 crossrefType "journal-article" @default.
- W2892722467 hasAuthorship W2892722467A5004222902 @default.
- W2892722467 hasAuthorship W2892722467A5028416824 @default.
- W2892722467 hasAuthorship W2892722467A5089968080 @default.
- W2892722467 hasConcept C104317684 @default.
- W2892722467 hasConcept C121332964 @default.
- W2892722467 hasConcept C12554922 @default.
- W2892722467 hasConcept C129536746 @default.
- W2892722467 hasConcept C148898269 @default.
- W2892722467 hasConcept C1491633281 @default.
- W2892722467 hasConcept C196843134 @default.
- W2892722467 hasConcept C202974441 @default.
- W2892722467 hasConcept C2779535977 @default.
- W2892722467 hasConcept C40692019 @default.
- W2892722467 hasConcept C54355233 @default.
- W2892722467 hasConcept C6047887 @default.
- W2892722467 hasConcept C74650414 @default.
- W2892722467 hasConcept C86803240 @default.
- W2892722467 hasConcept C87073359 @default.
- W2892722467 hasConcept C95444343 @default.
- W2892722467 hasConceptScore W2892722467C104317684 @default.
- W2892722467 hasConceptScore W2892722467C121332964 @default.
- W2892722467 hasConceptScore W2892722467C12554922 @default.
- W2892722467 hasConceptScore W2892722467C129536746 @default.
- W2892722467 hasConceptScore W2892722467C148898269 @default.
- W2892722467 hasConceptScore W2892722467C1491633281 @default.
- W2892722467 hasConceptScore W2892722467C196843134 @default.
- W2892722467 hasConceptScore W2892722467C202974441 @default.
- W2892722467 hasConceptScore W2892722467C2779535977 @default.
- W2892722467 hasConceptScore W2892722467C40692019 @default.
- W2892722467 hasConceptScore W2892722467C54355233 @default.
- W2892722467 hasConceptScore W2892722467C6047887 @default.
- W2892722467 hasConceptScore W2892722467C74650414 @default.
- W2892722467 hasConceptScore W2892722467C86803240 @default.
- W2892722467 hasConceptScore W2892722467C87073359 @default.
- W2892722467 hasConceptScore W2892722467C95444343 @default.
- W2892722467 hasFunder F4320321079 @default.
- W2892722467 hasLocation W28927224671 @default.
- W2892722467 hasLocation W28927224672 @default.
- W2892722467 hasOpenAccess W2892722467 @default.
- W2892722467 hasPrimaryLocation W28927224671 @default.
- W2892722467 hasRelatedWork W1567474072 @default.
- W2892722467 hasRelatedWork W1862219836 @default.
- W2892722467 hasRelatedWork W2002753521 @default.
- W2892722467 hasRelatedWork W2009472873 @default.
- W2892722467 hasRelatedWork W2025589534 @default.
- W2892722467 hasRelatedWork W2028678167 @default.
- W2892722467 hasRelatedWork W2139043462 @default.
- W2892722467 hasRelatedWork W2143718816 @default.