FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2892725021> ?p ?o ?g. }

• W2892725021 abstract "Electronic health data are routinely used for population drug studies. Due to the ethical dilemma in carrying out experimental drug studies on pregnant women, the effects of medication usage during pregnancy on fetal and maternal outcomes are largely evaluated using this data collection medium. One major limitation in this type of study is the delayed inclusion of pregnancies in the cohort. For example, in the province of Quebec, Canada, a major pregnancy cohort only captured pregnancies after 20 weeks gestation. The purpose of this study was to demonstrate three methods that can be used to assess the extent of selection bias due to the delayed inclusion of pregnancies. We use causal directed acyclic graphs to explain the source of this selection bias. In an example involving a cohort of pregnant asthmatic women reconstructed from the linkage of administrative health databases from the province of Quebec, we use numerical derivations, a simulation study and a sensitivity analysis to investigate the potential for bias and loss of power due to the delayed inclusion. We find that this selection bias can be partially mitigated by controlling for variables related to (spontaneous or therapeutic) abortion and the outcome of interest. The three proposed methods allow for the pre and post hoc ascertainment of the bias. While delayed pregnancy inclusion selection bias (which includes live birth bias) can produce substantial bias in pregnancy drug studies, all three methods are effective at producing estimates of the size of the bias." @default.
• W2892725021 created "2018-10-05" @default.
• W2892725021 creator A5013452986 @default.
• W2892725021 creator A5071840675 @default.
• W2892725021 date "2018-09-21" @default.
• W2892725021 modified "2023-10-03" @default.
• W2892725021 title "Methods for the assessment of selection bias in drug safety during pregnancy studies using electronic medical data" @default.
• W2892725021 cites W1108934011 @default.
• W2892725021 cites W1567806054 @default.
• W2892725021 cites W1582406977 @default.
• W2892725021 cites W1599147948 @default.
• W2892725021 cites W1603973565 @default.
• W2892725021 cites W1948463496 @default.
• W2892725021 cites W1971008606 @default.
• W2892725021 cites W1978209044 @default.
• W2892725021 cites W1988085768 @default.
• W2892725021 cites W1992882281 @default.
• W2892725021 cites W1997700012 @default.
• W2892725021 cites W2000748821 @default.
• W2892725021 cites W2005305067 @default.
• W2892725021 cites W2010505816 @default.
• W2892725021 cites W2013472399 @default.
• W2892725021 cites W2018147971 @default.
• W2892725021 cites W2023040232 @default.
• W2892725021 cites W2045337585 @default.
• W2892725021 cites W2048601894 @default.
• W2892725021 cites W2054774416 @default.
• W2892725021 cites W2058081866 @default.
• W2892725021 cites W2062594082 @default.
• W2892725021 cites W2072847588 @default.
• W2892725021 cites W2075031358 @default.
• W2892725021 cites W2083721602 @default.
• W2892725021 cites W2098564762 @default.
• W2892725021 cites W2106432307 @default.
• W2892725021 cites W2106526814 @default.
• W2892725021 cites W2112178157 @default.
• W2892725021 cites W2112721631 @default.
• W2892725021 cites W2112746019 @default.
• W2892725021 cites W2136397662 @default.
• W2892725021 cites W2143891888 @default.
• W2892725021 cites W2159399209 @default.
• W2892725021 cites W2163736307 @default.
• W2892725021 cites W2171478866 @default.
• W2892725021 cites W2317919109 @default.
• W2892725021 cites W2576556180 @default.
• W2892725021 cites W2620938002 @default.
• W2892725021 cites W2892725021 @default.
• W2892725021 cites W4292082006 @default.
• W2892725021 cites W4294553991 @default.
• W2892725021 cites W4327766790 @default.
• W2892725021 cites W4371576741 @default.
• W2892725021 cites W2017166875 @default.
• W2892725021 doi "https://doi.org/10.1002/prp2.426" @default.
• W2892725021 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6149369" @default.
• W2892725021 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30258633" @default.
• W2892725021 hasPublicationYear "2018" @default.
• W2892725021 type Work @default.
• W2892725021 sameAs 2892725021 @default.
• W2892725021 citedByCount "7" @default.
• W2892725021 countsByYear W28927250212019 @default.
• W2892725021 countsByYear W28927250212020 @default.
• W2892725021 countsByYear W28927250212021 @default.
• W2892725021 countsByYear W28927250212022 @default.
• W2892725021 crossrefType "journal-article" @default.
• W2892725021 hasAuthorship W2892725021A5013452986 @default.
• W2892725021 hasAuthorship W2892725021A5071840675 @default.
• W2892725021 hasBestOaLocation W28927250211 @default.
• W2892725021 hasConcept C126322002 @default.
• W2892725021 hasConcept C131872663 @default.
• W2892725021 hasConcept C142724271 @default.
• W2892725021 hasConcept C201903717 @default.
• W2892725021 hasConcept C2778642596 @default.
• W2892725021 hasConcept C2779234561 @default.
• W2892725021 hasConcept C2908647359 @default.
• W2892725021 hasConcept C40423286 @default.
• W2892725021 hasConcept C54355233 @default.
• W2892725021 hasConcept C71924100 @default.
• W2892725021 hasConcept C72563966 @default.
• W2892725021 hasConcept C86803240 @default.
• W2892725021 hasConcept C88629717 @default.
• W2892725021 hasConcept C99454951 @default.
• W2892725021 hasConceptScore W2892725021C126322002 @default.
• W2892725021 hasConceptScore W2892725021C131872663 @default.
• W2892725021 hasConceptScore W2892725021C142724271 @default.
• W2892725021 hasConceptScore W2892725021C201903717 @default.
• W2892725021 hasConceptScore W2892725021C2778642596 @default.
• W2892725021 hasConceptScore W2892725021C2779234561 @default.
• W2892725021 hasConceptScore W2892725021C2908647359 @default.
• W2892725021 hasConceptScore W2892725021C40423286 @default.
• W2892725021 hasConceptScore W2892725021C54355233 @default.
• W2892725021 hasConceptScore W2892725021C71924100 @default.
• W2892725021 hasConceptScore W2892725021C72563966 @default.
• W2892725021 hasConceptScore W2892725021C86803240 @default.
• W2892725021 hasConceptScore W2892725021C88629717 @default.
• W2892725021 hasConceptScore W2892725021C99454951 @default.
• W2892725021 hasFunder F4320334506 @default.
• W2892725021 hasIssue "5" @default.
• W2892725021 hasLocation W28927250211 @default.
• W2892725021 hasLocation W28927250212 @default.
• W2892725021 hasLocation W28927250213 @default.

• next